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Stem Cell Center advancing treatments, officials say

Posted: March 11, 2014 at 12:44 pm

Topeka Eight months after the establishment of the Midwest Stem Cell Therapy Center at Kansas University Medical Center, the center is conducting clinical trials and advancing treatments for numerous diseases, KU officials said Monday.

"We are very excited about the work that is going on," said Dr. Doug Girod, executive vice chancellor of the KU Medical Center.

Dr. Buddhadeb Dawn, the center's director, detailed clinical trials that are under way and several in the planning stages to the Senate Ways and Means Committee.

"These trials will help local patients to get access to stem cell therapy," Dawn said. "Kansas can be a leader in providing stem cell treatments."

Created last year by the Legislature and Gov. Sam Brownback, the center will work on adult stem cell, cord blood and related stem cell research, providing therapies to patients and serving as a clearinghouse for physicians on cutting-edge treatments.

The center is prohibited from using embryonic stem cells or cells taken from aborted fetal tissue. Abortion opponents oppose human embryonic stem cell research because it involves the destruction of the embryo.

David Prentice, senior fellow for life sciences of the Family Research Council, said the center was unique in the country.

Prentice, who was involved in the development of the center and is on the center's advisory board as a representative of the scientific community, said, "I do want to reemphasize the focus on the center is patient-centered," while also working on education, clinical trials and research.

The FRC describes itself as a Christian organization promoting the traditional family unit and the Judeo-Christian value system. Its critics say it spreads anti-gay propaganda.

State Sen. Jeff Melcher, R-Overland Park, said the research sounded exciting but that he was concerned that the advisory board had no business people on it to secure private and business funding.

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US foundation funds ReNeuron stem cell therapy

Posted: March 11, 2014 at 12:43 pm

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A US-based charity has agreed to provide funding and access to clinical expertise for ReNeuron's retinal stem cell therapy candidate for a degenerative eye disease.

Shares in ReNeuron rose 8.8% to 3.54p on the news.

The Foundation for Fighting Blindess has agreed to provide further funding towards the AIM-listed company's late pre-clinical work on its stem cell therapy candidate for retinitis pigmentosa, together with resources in support of preparations for initial clinical trials such as access to its network of expert pre-clinical and clinical advisers.

The charity has previously funded pre-clinical work on its ReN003.

ReNeuron's Chief Scientific Officer, John Sinden, said: "We are delighted that the Foundation Fighting Blindness will be supporting the development of our ReN003 therapeutic candidate for retinitis pigmentosa. In particular, the Foundation's extensive knowledge, experience and network of advisers will be invaluable to us as we look to progress the ReN003 programme into its clinical phase."

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US foundation funds ReNeuron stem cell therapy

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Protein synthesis studied in stem cells for the first time

Posted: March 11, 2014 at 2:46 am

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A new breakthrough in stem cell research has occurred, thanks to scientists at the Children's Medical Center Research Institute at UT Southwestern Medical Center in Dallas, Texas.

The researchers claim that protein synthesis - an essential biological process - can be studied in adult stem cells. This is something that scientists have been previously unable to accomplish.

It is believed that many degenerative diseases and some cancers are linked with mutations that affect the process of protein synthesis. But experts have been unable to pinpoint why this happens.

Therefore, the team's discovery is important in improving understanding of protein synthesis and why changes in the process are linked with the development of disease.

The research built on previous work that used a modified antibiotic, called puromycin, to make it possible to see and measure the amount of protein that is being synthesized in the body.

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Retracted: Study That Found Acid Converts Blood Cells Into Stem Cells

Posted: March 11, 2014 at 2:46 am

S

This is a game changer, folks. Whereas mining stem cells has been either an ethical quandary or a months-long affair, scientist can now turn any old blood cells into stem cells in just 30 minutesby dipping them in acid.

That's right. Take blood cells, add acid, get stem cells. It's as simple as it sounds.

A team of Japanese scientists stumbled upon the method after observing a similar phenomenon in plants, where environmental stress can morph an ordinary cell into an immature one. New plants could then grow from the immature cell. This has also been known to happen in birds and reptiles, so the team from the Riken Center for Developmental Biology set out to see if something similar could happen with mammals.

They started with mice, of course. Sure enough, when they exposed blood cells from mice to acid, a transformation began. While some of the blood cells died, many became stem cells within a couple of days. "It looks a bit too good to be true, but the number of experts who have reviewed and checked this, I'm sure that it is," Chris Mason, professor of regenerative medicine at University College London, told the BBC. "If this works in people as well as it does in mice, it looks faster, cheaper and possibly safer than other cell reprogramming technologiespersonalized reprogrammed cell therapies may now be viable."

The breakthrough was described by other scientists as "remarkable," "revolutionary," and "a game changer." Why? Well, if you've been following the promise and perils of stem cell research, then you know that the issue is both controversial and complicated. At first, scientists mined stem cells directly from embryos, but that involved destroying the embryos. In 2006, teams from Japan and the United Kingdom developed a new method, whereby they introduced certain genes that caused cells to reprogram themselves, becoming stem cells. That discovery won them the Nobel Prize in 2012, but it's also expensive and time-consuming. Other experimental methods are in the works.

This new discovery not only means that we can produce stem cells cheaply and quickly but also potentially cut through the ethical debate, because no embryos would be harmed. If it works in humans, that is. Of course, there's plenty more research to be done before scientists can fully understand the process and develop methods for stem cell research. But hot damn, this is good news. [New Scientist, BBC]

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11 WebOps 1 – Video

Posted: March 11, 2014 at 2:45 am


11 WebOps 1
This company provides a service whereby stem cell biopsies can be stored fresh from the operating table in a specially deigned canister which maintains an in...

By: Global Alliance for Regenerative Medicine, Roatan, Honduras

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11 WebOps 1 - Video

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Histogen Aesthetics Acquires CellCeuticals Biomedical Skin Treatments

Posted: March 11, 2014 at 2:45 am

San Diego, CA (PRWEB) March 10, 2014

Histogen Aesthetics, a subsidiary of regenerative medicine company Histogen, Inc. focused on skin care and cosmeceuticals, announced today that the Company has acquired the CellCeuticals Biomedical Skin Treatments line of skincare products.

Histogen Aesthetics will continue sales of the eleven existing CellCeuticals Biomedical Skin Treatments skincare products, while bringing new innovation to the line through the addition of a unique regenerative medicine technology, working to improve skin aging at a cellular level.

We have long admired the science, clinical data and elegant formulas behind the CellCeuticals line, and see it as an ideal fit for our recently revitalized aesthetics subsidiary, said Dr. Gail K. Naughton, CEO and Chairman of Histogen, Inc. We are very excited to begin infusing unique cell-signaling factors into the CellCeuticals regimen, to truly transform skin one cell at a time.

Dr. Naughton has spent more than 30 years in tissue engineering and regenerative medicine, and holds over 100 patents in the field. She founded Histogen in 2007, focused on developing therapies that work to stimulate the stem cells in the body to regenerate tissues and organs. Through this work, she has also seen how different compositions of human proteins can have cosmetic benefits, particularly in anti-aging and rejuvenation.

I am pleased that the CellCeuticals Biomedical Skin Treatments will evolve, and see Histogen Aesthetics as an excellent home for this innovative product line, said Paul Scott Premo, co-founder of CellCeuticals Skin Care, Inc. I believe the addition of this regenerative medicine technology will be the opportunity to introduce a new generation of products that are the vanguard of regenerative skin care.

The CellCeuticals system is made up of eleven distinctive products including the Extremely Gentle Skin Cleanser, CellGenesis Regenerative Skin Treatment, and PhotoDefense Color Radiance SPF55+ with proprietary and patented PhotoPlex technology. The line is currently available at retailers including QVC.com, Dermstore.com, and Nordstrom.com, as well as http://www.cellceuticalskincare.com.

About Histogen Aesthetics Histogen Aesthetics LLC, formed in 2008 as a subsidiary of Histogen, Inc., focuses on the development of innovative skin care products utilizing regenerative medicine technology. Histogen Aesthetics technology is based on the expertise of founder Dr. Gail K. Naughton, in which fibroblasts are grown under unique conditions, producing a complex of naturally-secreted proteins and synergistic bio-products known to stimulate skin cells to regenerate and rejuvenate tissues. In 2014, Histogen Aesthetics acquired CellCeuticals Biomedical Skin Treatments, a line of scientifically-proven products that reactivate cells to help aging skin perform and look healthier and younger. For more information, visit http://www.cellceuticalskincare.com.

About Histogen Histogen is a regenerative medicine company developing solutions based upon the products of cells grown under proprietary conditions that mimic the embryonic environment, including low oxygen and suspension. Through this unique technology process, newborn cells are encouraged to naturally produce the vital proteins and growth factors from which the Company has developed its rich product portfolio. Histogen's lead product, Hair Stimulating Complex (HSC) has shown success in two Company-sponsored clinical trials as an injectable treatment for alopecia. In addition, the human multipotent cell conditioned media produced through Histogen's process is also being researched for oncology applications, and in orthopedics through joint venture PUR Biologics, LLC. For more information, please visit http://www.histogen.com.

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Okyanos CEO Matt Feshbach Announces Appointment of Institutes Marketing Executive Erika Rosenthal to International …

Posted: March 11, 2014 at 2:40 am

Freeport, The Bahamas (PRWEB) March 10, 2014

Matt Feshbach, CEO of Okyanos Heart Institute whose mission it is to bring a new standard of care and better quality of life to patients with coronary artery disease using cardiac stem cell therapy has announced the appointment of Okyanos senior vice president of marketing, Erika Rosenthal, to the International Stem Cell Society (STEMSO) Advisory Board. She will advise the trade organization in a communications capacity to benefit the membership and the mission.

STEMSO is a member-based, international, non-profit 501(c) 6 trade association which promotes the interests of organizational members of the global, adult stem cell healthcare community. STEMSO provides information, education, resources, advocacy and public awareness for the advancement of adult stem cell research and therapy. The organization recently hosted a global regenerative medicine conference in Freeport, The Bahamas, entitled, Bridging the Gap: Research to Point of Care which brought together experts in adult stem cell therapy and regulations to discuss commercialization of therapies for chronic disease in a safe, ethical, and compliant manner.

STEMSO is an important organization to the field of stem cell therapy and research, said Feshbach. Communications and healthcare are both fields in which Erika excels, and so I am pleased to see her lend her expertise for an important cause. I look forward to the Okyanos Heart Institute executive team continuing with such efforts for the greater good of medicine.

Rosenthal was a 2008 recipient of the National Association of Women Business Owners Business Woman of the Year award, and was recognized in Business Leader Magazine as a Woman Extraordinaire, for her business accomplishments and contributions to the non-profit community. She is a former faculty member of the University of California where she taught Marketing and Hospitality Management.

It is indeed an honor to work with STEMSO to advance their cause to help advance adult stem cell research and therapy worldwide, and to bring together leading researchers, physicians, regulators and scientists to set standards for ethical and responsible delivery of therapies as they become available to the public worldwide, said Rosenthal. It is an exciting time in medicine, and STEMSO is greatly needed to bring collaboration and guidance between this impressive member group of thought leaders.

STEMSO is pleased to have Erika Rosenthal participate on STEMSOs Advisory Board, said Douglas Hammond, president of STEMSO. Non-profit trade associations are only as strong as their member participation and leadership allows. If other members or prospective organizational members were to support STEMSO as Okyanos Heart Institute and Erika Rosenthal, there would be no limit to STEMSOs impact in the Regenerative Medicine Industry.

About Okyanos Heart Institute: (Oh key AH nos) Based in Freeport, The Bahamas, Okyanos Heart Institutes mission is to bring a new standard of care and a better quality of life to patients with coronary artery disease using cardiac stem cell therapy. Okyanos adheres to U.S. surgical center standards and is led by Chief Medical Officer Howard T. Walpole Jr., M.D., M.B.A., F.A.C.C., F.S.C.A.I. Okyanos Treatment utilizes a unique blend of stem and regenerative cells derived from ones own adipose (fat) tissue. The cells, when placed into the heart via a minimally-invasive procedure, can stimulate the growth of new blood vessels, a process known as angiogenesis. Angiogenesis facilitates blood flow in the heart, which supports intake and use of oxygen (as demonstrated in rigorous clinical trials such as the PRECISE trial). The literary name Okyanos, the Greek god of rivers, symbolizes restoration of blood flow.

END

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Regenestem and Global Stem Cells Group Announce Alliance With Eric Yalung, M.D. to Build First Regenestem Clinic in …

Posted: March 11, 2014 at 2:40 am

Miami (PRWEB) March 10, 2014

Regenestem, Inc., a division of Global Stem Cells Group, has announced plans to build the first Regenestem brand clinic in the Philippines. The planned, 22,000 square foot, state-of-the-art medical facility in Manila will focus on providing the latest stem cell-based anti-aging and cosmetic therapies available, eliminating the need for invasive surgery.

Regenestem is collaborating with distinguished Philippine Cosmetic Surgeon Eric Yalung, M.D. of the Cosmetic Surgery Institute-Manila, Inc. to create the stem cell therapy center, offering the most advanced protocols in cosmetic cellular medicine to patients from around the world.

The new Regenestem clinic will be headed by Yalung, a prominent and popular cosmetic surgeon in Manila who has built a reputation for incorporating the latest, most modern and least-invasive techniques in aesthetic medicine into his practice. Yalung will be joined by a team of talented stem cell specialists to provide patient treatment and follow-up care under the Regenestem brand.

Regenestem currently offers stem cell treatments for arthritis, autism, chronic obstructive pulmonary disease (COPD), diabetes and multiple sclerosis among other conditions at various facilities worldwide

As part of its commitment to maintaining the highest standards in service and technology, Regenestem provides an international staff and the leading cellular therapies available.

All Regenestem facilities are certified for the medical tourism market, and staff physicians are board-certified or board-eligible. Regenestem clinics provide services in more than 10 specialties, attracting patients from the United States and around the world.

For more information, visit the Regenestem website, email info(at)regenstem(dot)com, or call 305-224-1858.

About Regenestem:

Regenestem, a division of the Global Stem Cells Group, Inc., is an international medical practice association committed to researching and producing comprehensive stem cell treatments for patients worldwide. Having assembled a highly qualified staff of medical specialistsprofessionals trained in the latest cutting-edge techniques in cellular medicineRegenestem continues to be a leader in delivering the latest protocols in the adult stem cell arena.

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Adult Stem Cells- A Medical Revolution in the Making – Video

Posted: March 10, 2014 at 11:43 pm


Adult Stem Cells- A Medical Revolution in the Making
Our bodies are made and rejuvenated by stem cells. Join us to learn about the latest advances in adult stem cell cell technology and how they will truly tran...

By: Notre Dame Science

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RSCI Don Margolis Stem Cells 101 Introduction – Video

Posted: March 10, 2014 at 10:40 am


RSCI Don Margolis Stem Cells 101 Introduction
The greatest medical science in the history of the world.

By: Repair Stem Cells

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