Posted: March 6, 2014 at 12:44 am
stem cell therapy treatment for Spastic Paraplegia by dr alok sharma, mumbai, india
improvement seen in just 5 days after stem cell therapy treatment for Spastic Paraplegia by dr alok sharma, mumbai, india. Stem Cell Therapy done date 7/1/20...
By: Neurogen Brain and Spine Institute
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stem cell therapy treatment for Spastic Paraplegia by dr alok sharma, mumbai, india - Video
Posted: March 6, 2014 at 12:44 am
stem cell therapy treatment for Spastic Diplegic cerebral palsy by dr alok sharma, mumbai, india
improvement seen in just 5 days after stem cell therapy treatment for Spastic Diplegic cerebral palsy by dr alok sharma, mumbai, india. Stem Cell Therapy don...
By: Neurogen Brain and Spine Institute
Posted: March 6, 2014 at 12:44 am
The Sultan bin Abdulaziz Humanitarian City (SAHC) announced Tuesday its intention to take stem cell transplantation to new heights by using the method to cure spinal cord injuries. The announcement was made by Prince Khaled bin Sultan, chairman of the Sultan bin Abdulaziz Al-Saud Foundation (SAAF), during the international spinal cord injury conference 2014, which kicked off at the SAHC headquarters on Tuesday. The theme of the conference, which ends on Thursday, is Toward a Better Quality of Life. The conference, first introduced in Australia and New Zealand, is being held for the first time in the Middle East. The technology, in collaboration with the US-based University of Miami, will revolutionize the scope of paralysis surgery in the Kingdom, making it a leader in the field. An accord on collaboration between the SAHC and the Miami Project to Cure Paralysis (MPCP), the first center in the US to receive approval from the supervisory board of the Food and Drug Administration for stem cell therapy, was also signed. Prince Khaled said that the transfer of this technology comes amid efforts to help families cope with the life-changing effects of spinal cord injuries. Prince Khaled said many people between the ages of 16 and 22 suffer such debilitating injuries. The MPCP works on several research and rehabilitation programs in the field of spinal cord and traumatic brain injury, he said. The transfer of this technology to the SAHC will make Saudi Arabia one of the first countries in the region to benefit from the revolutionary treatment of spinal cord injury through stem cell research. SAHC Executive President Abdullah Zarah said the conference would address the latest findings of modern science in the field of spinal cord injury and stem cell transplantation. Around 1,500 Saudis are afflicted with spinal cord injuries every year due to accidents. Rizman Hamid, a senior neurology lecturer at University College London, told Arab News that being afflicted with this type of injury is a lifelong condition. Such critical ailments require follow-up, with radiological investigation to optimize bladder function. Patients should undergo regular investigation as a means of detecting potential problems in the bladder, which can lead to kidney damage, he said. He added that another major problem resulting from spinal cord injuries, especially among women, is urinary incontinence, which has severe and adverse effects on patients. This condition can be cured through a procedure known as the transobtruator tape. This is a minimally invasive procedure that has good long-term results, he said. Firas Sirhan, director of the Center of Excellence for Telehealth and Assisted Living (CETAL) at Buckinghamshire New University in Middlesex, England, said that the use of technology and health care practice is becoming more visible in the treatment and management of spinal cord injuries. Telehealth represents an entirely new way of managing injury that does not easily fit within existing health care frameworks, he said. The use of the telehealth model has contributed to empowering patients to become more involved in the self-management of their condition. Telehealth could be an effective tool that contributes to allowing health care professionals, as well as patients, to recognize and identify any changes in medical conditions. He added that the center can assist in developing packages that combine tested clinical service models with assessed technology to present workable telehealth services based on specific needs.
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Stem cell technology to cure spinal cordv injuries introduced in KSA
Posted: March 5, 2014 at 11:44 pm
(WMC-TV) - More than 60 percent of American households include at least one pet, and for many of us they are more like family than a four-legged friend.
Eight-year-old Sadie suffers from debilitating arthritis. To owners Greg and Marsha James, she is a miracle dog.
"She's my little girl, she's my baby," said owner Marsha. "I didn't know if we could do anything and what we could do, I thought we were gonna lose her."
Last year she could not even walk, but a scientific breakthrough using her own stem cells put the pep back in her step.
"Stem cell is used to treat chronic arthritic conditions," said Dr. Kathy Mitchener, DVM at Angel Care Center for Pets.
Dr. Kathy Mitchener removed a few ounces of fat from Sadie's tummy; a lab extracted the stem cells, which were then re-injected into her trouble spots.
"If there's joint destruction, if there's changes in metabolism then they change themselves and multiply to help address those issues," said Mitchener.
Stem cell treatment proves to be just one of many medical miracles at the Angel Care Cancer Center for Pets in Bartlett.
Take Rylee for example. The 2-year-old golden retriever has an unusual type of lymphoma.
"Riley was very young, and that's very , very frightening to have such a devastating disease," said Mitchener.
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Stem cell treatment, other breakthroughs giving pets longer, healthier lives
Posted: March 5, 2014 at 6:51 am
Researchers at London's Great Ormond Street Hospital aim to grow a human ear via stem cells taken from a patient's fat tissue. Relatively little attention has been given to the reconstruction of damaged cartilage around the cranial area, however the new method is hoped to modernize this area of reconstructive surgery.
Currently to repair damaged or non-existent cartilage in the ear, an operation is usually carried out when the patient is a child. Cartilage is extracted from the patient's ribs and painstakingly crafted into the form of an ear, before being grafted back onto the individual.
Whilst this method of reconstruction achieves good results, it also has some unpleasant side effects. The patient is left with a permanent defect around the area from where the cells were harvested, as the cartilage between the ribs does not regenerate. Since any operation to replace the cartilage in the ear is for cosmetic purposes only, curing one defect by creating another (albeit in a less obvious place) is not an optimal solution.
The cartilage cells used in the new technique are engineered from mesenchymal stem cells, extracted from the child's abdominal adipose tissue (fat). The benefit of this new system is that unlike the cartilage in the ribs, the adipose tissue regenerates, therefore leaving no long-term defect to the host. There is also the potential to begin reconstructive treatment with stem cells derived from adipose tissue earlier than previously possible, as it takes time for the ribs to grow enough cartilage to undergo the procedure.
Dr. Patrizia Ferretti, a researcher working on the project, told Gizmag, One of the main benefits in using the patients own stem cells is that there is no need for immune suppression which would not be desirable for a sick child, and would reduce the number of severe procedures a child needs to undergo."
To create the form of the ear, a porous polymer nano-scaffold is placed in with the stem cells. The cells are then chemically induced to become chondrocytes (cartilage cells) while growing into the holes in the scaffold to create the shape of the ear.
"Cellularized scaffolds integrate much better than fully synthetic implants, which are more prone to extrusion and infection," Dr. Ferretti explained.
The new, and potentially more advantageous technique would replace the current set of procedures in the treatment of defects in cartilage in children such as microtia, a condition which prevents the ear from forming correctly.
Dr. Ferretti continued that While we are developing this approach with children with ear defects in mind, it could ultimately be utilized in other types of reconstructive surgery both in children and adults." Such reconstructive technology has the potential to be invaluable in improving the quality of life of those who have been involved in a disfiguring accident or even those injured in the line of service.
Source: Journal of Nanomedicine
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Researchers hope to grow human ears from fat tissue
Posted: March 5, 2014 at 6:51 am
University of Wisconsin-Madison researchers recently demonstrated advancements in the differentiation of human embryonic stem cells, according to a university press release.
The researchers presented their findings in a paper centered around the geometries of substrates, molecules that bind with acting enzymes to allow chemical reactions to occur, as they relate to stem and heart-muscle cells, according to the release.
The research focused on the development of stem cells into mature-heart muscle
cells, otherwise known as cardiomyocytes, and the optimization of the these cells function.
Wendy Crone, a professor of engineering physics, biomedical engineering and material science, and lead author of the paper said cardiomyocytes derived from stem cells could be groundbreaking in the scientific and medical field.
Im hoping that our research will be able to help better treatments for disease and particularly heart disease, Crone said.
Moreover, Crones study could lead to progress in tissue engineering and drug research.
We can use [the cells] for things like testing out the side effects for drugs, Crone said. Frequently new drugs have negative impact on heart function.
Crone also expressed in the release one of her teams biggest challenges was finding a suitable environment for the stem cells to exist outside of the body.
Its really hard to culture stem cells effectively and to provide them with an environment thats going to help them to thrive and differentiate in the way you want, Crone said in the release.
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UW-Madison researchers advance understanding of stem cells, heart-muscle cells
Posted: March 5, 2014 at 6:51 am
PUBLIC RELEASE DATE:
4-Mar-2014
Contact: Jen Middleton jen.middleton@ed.ac.uk 44-131-650-6514 University of Edinburgh
Horses suffering from neurological conditions similar to those that affect humans could be helped by a breakthrough from stem cell scientists.
Researchers who are the first to create working nerve cells from horse stem cells say the advance may pave the way for cell therapies that target conditions similar to motor neurone disease.
The research could also benefit horses affected by grass sickness, a neurological condition that affects around 600 horses a year in the UK.
Little is known about the disease, which causes nerve damage throughout the body. It is untreatable and animals with the most severe form usually die or have to be put down.
The advance by the University of Edinburgh's Roslin Institute will provide a powerful tool for those studying horse diseases. It will also help scientists to test new drugs and treatments.
The researchers took skin cells from a young horse and turned them into stem cells using a technique that was originally developed for human cells. The reprogrammed cells are pluripotent, which means they can be induced to become any type of cell in the body.
The team used them to create nerve cells in the laboratory and tested whether they were functional by showing that they could transmit nerve signals in a test tube.
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Horses set to gain health benefits from stem cell advance
Posted: March 5, 2014 at 6:47 am
What many didnt realise was that the freaky looking ear was never grown, had nothing to do with genetic engineering and wasnt really a scientific breakthrough at all! Instead, it served as the publics introduction to the new field of tissue engineering, through which researchers attempt to create replacement tissues in the laboratory by combining resorbable materials with stem cells.
Tissue engineers, like those in my laboratory at Kings College London, work to build everything from cartilage to fix creaky arthritic knees to coronary arteries to patch up heart patients. What looked like a human ear grown on a mouse was simply what we call a scaffold, an implantable 3D structure made of a plastic that safely dissolves in the body.
Twenty years later, a UCL-based team led by Dr Patrizia Ferretti is continuing to build on this work to reconstruct ears. Surgeons currently treat microtia, a condition in which children are born with a malformed or missing ear, by taking cartilage from the patients rib and implanting it in the head to form something that looks like an ear.
Dr Ferretti hopes to eliminate the need for this second cartilage-harvesting surgery by growing ear cartilage in the laboratory.
The difference here is that whereas in the 1990s tissue engineers thought that merely forming a scaffold of the correct shape and size would allow us to create a tissue, we now understand that a stem cells perception of its nano-environment plays an important role in determining the tissue it creates.
In short, we can now tailor a scaffold with nano-cues that tell a stem cell to become a liver cell instead of lung.
Dr Ferrettis scaffold does just this. Her team utilises a new nanocaged POSS-PCU scaffold to coax stem cells collected from fat to form cartilage whilst the scaffold slowly melts away.
This exciting material came to light in 2011 when it was used to replace the windpipe of a patient who had to have his own removed because of cancer.
The scaffold here instructed stem cells to create the windpipes lining, essentially using the body as an incubator to help direct their fate. This time, the UCL team utilised a cocktail of chemicals to help push the stem cells to make cartilage, so it remains to be seen if the scaffold will similarly drive ear cartilage formation once placed in the body.
What is clear, however, is that the field of tissue engineering is progressing at a remarkable pace and tailor-made tissues to treat a range of conditions are a real possibility in the near future."
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Commentary: field of tissue engineering is progressing at remarkable pace
Posted: March 5, 2014 at 6:44 am
stem cell therapy treatment for Cerebral Palsy with Mental Retardation by dr alok sharma, mumbai
improvement seen in just 5 daysafter stem cell therapy treatment for Cerebral Palsy with Mental Retardation by dr alok sharma, mumbai, india. Stem Cell Thera...
By: Neurogen Brain and Spine Institute
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stem cell therapy treatment for Cerebral Palsy with Mental Retardation by dr alok sharma, mumbai - Video
Posted: March 4, 2014 at 12:40 pm
RSCI Don Margolis Stem Cells 101 #02
The difference between Embryonic and Repair Stem Cells.
By: Repair Stem Cells
