Posted: December 29, 2013 at 9:40 pm
Longevity With Doctor Wilcox - What makes you age - Telomeres - Stem Cells
Dr Wilcox discusses the aging process, telomeres, and stem cells KLAV Las Vegas 1234 AM Monday Thursday 10am to 11am.
By: Infinity Medical Consulting
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Longevity With Doctor Wilcox - What makes you age - Telomeres - Stem Cells - Video
Posted: December 28, 2013 at 4:45 pm
stem cell therapy in chandigarh
Performing a hair transplant is as much about craftsmanship and design as it is about microsurgery. Each case is different and a successful result depends on...
By: rinkle hairtransplant
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stem cell therapy in chandigarh - Video
Posted: December 27, 2013 at 5:43 pm
A release from the University of California-Los Angleles written by Shaun Mason reports that researchers at UCLA's Eli and Edythe Broad Center of Regenerative Medicine and Stem Cell Research have discovered a mechanism by which certain adult stem cells suppress their ability to initiate skin cancer during their dormant phase an understanding that could be exploited for better cancer-prevention strategies. The study, led by Andrew White and William Lowry, was published online Decemeber 15th 2013 in the journal Nature Cell Biology.
The release notes that hfollicle stem cells, the tissue-specific adult stem cells that generate the hair follicles, are also the cells of origin for cutaneous squamous cell carcinoma, a common skin cancer. These stem cells cycle between periods of activation during which they can grow and quiescence (when they remain dormant).
White and Lowry applied known cancer-causing genes to hair follicle stem cells of laboratory mice and found that during the cells dormant phase, they could not initiate skin cancer. Once the cells were in their active period, however, they began growing cancer.
The release quotes White as saying, "We found that this tumor suppression via adult stem cell quiescence was mediated by PTEN, a gene important in regulating the cell's response to signaling pathways. Therefore, stem cell quiescence is a novel form of tumor suppression in hair follicle stem cells, and PTEN must be present for the suppression to work."
The team believes that understanding cancer suppression through quiescence could better inform preventative strategies for certain patients, such as organ transplant recipients, who are particularly susceptible to squamous cell carcinoma, and for those taking the drug vemurafenib for melanoma, another type of skin cancer. The study also may reveal parallels between squamous cell carcinoma and other cancers in which stem cells have a quiescent phase.
Posted: December 27, 2013 at 5:43 pm
AUTOLOGOUS Adipose Stem Cells
Stem Cell Therapy is not a new technology. As a matter of fact it has been around for more that 60 years now. The problem is most people know it as a bone marrow transplant. And well when you finish saying that people are already screaming "That's Painful". A bone marrow transplant essentially extracts stem cells from your own bone marrow and then returns them back to you. It has been used to help people suffering from conditions like Leukemia and Lymph Node Cancer.
How does it work? Stem Cells hone in on "chemokine" signals that are secreted by injury. When they arrive they alert regenerative cells to go to work and repair the damage, or grow tissue.
At birth, the human body has around 80 million active stem cells working. At age 40 we have less than 25 million active stem cells working. Therefore it takes longer for the body to heal and in some cases damage is often ignored. This is the aging or degeneration process of the body.
In 1998 a little known about Bio Tech Company discovered that there was an enormous amount of stem cells in abdominal fat, commonly referred to as Adipose fat. In fact there are about 1-2 million stem cells and regenerative cells in 1 cc of abdominal fat. Bone marrow contains less than 10% of that. The stem cells in the abdomen are in a dormant or inactive state. The challenge lay only in how to activate them.
In early 2000 the problem had been solved. A special separation process was used to isolate stem cells from abdominal fat and a perfected heliotherapy process activated the stem cells. These super-charged stem cells were now ready to go to work healing your body.
Fat Stem Cell Therapy has been used for over a decade now as therapy for a variety of medical problems as well as an alternative to painful cosmetic surgery. Fat Stem Cell Therapy can help patients suffering from medical conditions such as, Osteoarthritis, Pulmonary Disease, and Diabetes Type II, as well as some Cosmetic Procedures like Face Lifts, Breast Augmentation, and Anti-Aging.
Infinite Horizons Medical Center and its association with a leading Bio Tech company are able to deliver these high tech therapies with precision, expertise and a level of care which rivals any in the world. These painless medical procedures uses the clients' own adult stem cells to treat clients' medical problems. The procedures themselves take roughly 3.5 - 7 hours to complete.
The procedure involves extracting autologous adipose stem cells, enriching them, activating the enriched stem cells and finally returning these stem cells back into the clients' body. The procedure only requires a local anesthetic, is 100% safe, 100% effective and there is a 0% chance of rejection. For more detailed information see our procedure page.
Infinite Horizons Medical Center has put together an incredible program for clients in search of medical treatment with fat stem cell therapy for, Pulmonary Disorders, like IPF or COPD, Diabetes Type II and Osteoarthritis. It has also put together special programs with fat stem cell therapy for cosmetic procedures like Anti-Aging, Breast Augmentation and Face Lifts.
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Fat Stem Cell Therapy | Medical Treatments Cosmetic Procedures
Posted: December 27, 2013 at 3:45 am
MELBOURNE: Doctors may soon be able to draw new bone, skin and muscle on to patients, after scientists created a pen-like device that can apply human cells directly on to seriously injured people.
The device contains stem cells and growth factors and will give surgeons greater control over where the materials are deposited.
It will also reduce the time the patient is in surgery by delivering live cells and growth factors directly to the site of injury, accelerating the regeneration of functional bone and cartilage, scientists said.
The device developed at the University of Wollongong (UOW) will eliminate the need to harvest cartilage and grow it for weeks in a lab.
The Bio Pen works similar to 3D printing methods by delivering cell material inside a bio-polymer such as alginate, a seaweed extract, protected by a second, outer layer of gel material.
The two layers of gel are combined in the pen head as it is extruded onto the bone surface and the surgeon draws with the ink to fill in the damaged bone section.
A low powered ultra-violet light source is fixed to the device that solidifies the inks during dispensing, providing protection for the embedded cells while they are built up layer-by-layer to construct a 3D scaffold in the wound site.
Once the cells are drawn onto the surgery site they will multiply, become differentiated into nerve cells, muscle cells or bone cells and will eventually turn from individual cells into a thriving community of cells in the form of a functioning a tissue, such as nerves, or a muscle.
The device can also be seeded with growth factors or other drugs to assist regrowth and recovery, while the hand-held design allows for precision in theatre and ease of transportation.
The BioPen prototype was designed and built using the 3D printing equipment in the labs at Wollongong and was handed over to clinical partners at St Vincents Hospital Melbourne, led by Professor Peter Choong, who will work on optimising the cell material for use in clinical trials.
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New pen-like device to repair broken bone
Posted: December 27, 2013 at 3:45 am
PITTSBURGH (KDKA) Hayley Mogul, 13, and her 9-year-old sister, Bari, have rare genetic mutations that cant be cured.
But their conditions have improved during a two-month stay at the Childrens Institute in Squirrel Hill.
Their mother, Robyn Mogul, says she and her husband brought them here from their home of Chicago.
Haley could communicate, Robyn says. She could do some things herself, where Bari does not eat on her own. Shes eating baby food; she drinks out of a bottle.
Feeding specialist Natalie Chalmers says Bari is making progress.
She was on baby food only, she recalls. So weve been moving on to pureed table foods, and now were working on her variety.
Originally, the girls parents didnt know a place like this existed.
After Bari turned 5, the two sisters were taken to the National Institutes of Health in Bethesda, Md., for the first of several visits.
Doctors finally recommended the Childrens Institute of Pittsburgh.
To be able to come here and have this help has just been amazing, their mother says.
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Sisters’ Stem Cells Donated In Hopes Of Helping Other Children
Posted: December 27, 2013 at 3:44 am
JTOG075 Paula Caray Stem Cell Treatments in Panama City
JTOG075 Paula Caray Stem Cell Treatments in Panama City.
By: Andy Reistetter
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JTOG075 Paula Caray Stem Cell Treatments in Panama City - Video
Posted: December 27, 2013 at 3:42 am
December 26th, 2013 11:42 pm Preventive Veterinary Medicine By: You Tube CreationRead More...
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Stem Cell Therapy Updates
Posted: December 27, 2013 at 3:42 am
Dr. Aidan R. Raney performs a checkup on heart attack patient Mark Athens, 52, on Tuesday, Dec. 17, at Scripps Green Hospital in La Jolla. Athens received a stem cell treatment to help his heart recover as part of a clinical trial to determine the treatments safety and effectiveness.
A new stem cell treatment may help heart attack patients do something once thought medically impossible regenerate dead heart muscle.
Scripps Health in La Jolla is one of three centers testing the therapy from Capricor, a Los Angeles biotech company. The cardiac stem cells are meant to boost the hearts natural ability to perform minor repairs. If it works, scars should shrink and functional heart muscle should grow.
Capricor gets the cells from donor hearts, grows them into the amount needed for treatment, then sends them to doctors taking part in what is called the Allstar trial. Doctors inject the cells into the coronary artery, where they are expected to migrate to the heart and encourage muscle regrowth.
The trial has successfully completed Phase 1, which mainly evaluates safety. On Dec. 17, Capricor said it had received permission to begin Phase 2, which will examine efficacy in about 300 patients who will get the treatment or a placebo. More information can be found at clinicaltrials.gov under the identifier NCT01458405.
The Allstar trial is funded with a $19.7 million disease team grant from the California Institute for Regenerative Medicine, or CIRM, the states stem cell agency.
This is a highly significant announcement for us at CIRM as its the first time weve funded a therapy into a Phase 2 clinical trial, Chairman Jonathan Thomas said in a Dec. 23 statement.
About 600,000 Americans die of heart disease annually, making it the leading cause of death, according to the Centers for Disease Control and Prevention in Atlanta. Even those surviving may be left permanently impaired, if the heart is severely damaged. These are the patients Capricor seeks to help.
Mark Athens received Capricors treatment on Sept. 25, about a month after having a moderate heart attack. The Encinitas resident was the last treated under Phase 1, said Scripps cardiologist Richard Schatz, who performed the procedure. It will take about six months to know whether the treatment worked, Schatz said.
Unlike many trials, Phase 1 was not placebo-controlled, so Athens knows he got the therapy. He appeared cheerful, smiling and bantering with his examining doctor during a Dec. 17 checkup at Scripps Green Hospital.
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Stem cells tested to repair damaged hearts
Posted: December 27, 2013 at 3:42 am
PUBLIC RELEASE DATE:
26-Dec-2013
Contact: Mary Beth O'Leary moleary@cell.com 617-397-2802 Cell Press
Stem cell-based gene therapy holds promise for the treatment of devastating genetic skin diseases, but the long-term clinical outcomes of this approach have been unclear. In a study online December 26th in the ISSCR's journal Stem Cell Reports, published by Cell Press, researchers evaluated a patient with a genetic skin disorder known as epidermolysis bullosa (EB) nearly seven years after he had undergone a gene therapy procedure as part of a clinical trial. The study revealed that a small number of skin stem cells transplanted into the patient's legs were sufficient to restore normal skin function, without causing any adverse side effects.
"These findings pave the way for the future safe use of epidermal stem cells for combined cell and gene therapy of epidermolysis bullosa and other genetic skin diseases," says senior study author Michele De Luca of the University of Modena and Reggio Emilia.
EB is a painful condition that causes the skin to be very fragile and to blister easily, and it can also cause life-threatening infections. Because there is no cure for the disease, current treatment strategies focus on relieving symptoms. To evaluate stem cell-based gene therapy as a potential treatment, De Luca and his colleagues previously launched a phase I/II clinical trial at the University of Modena and recruited an EB patient named Claudio. The researchers took skin stem cells from Claudio's palm, corrected the genetic defect in these cells, and then transplanted them into Claudio's upper legs.
In the new study, De Luca and his team found that this treatment resulted in long-term restoration of normal skin function. Nearly seven years later, Claudio's upper legs looked normal and did not show signs of blisters, and there was no evidence of tumor development. Remarkably, a small number of transplanted stem cells was sufficient for long-lasting skin regeneration.
Even though Claudio's skin had undergone about 80 cycles of renewal during this time period, the transplanted stem cells still retained molecular features of palm skin cells and did not adopt features of leg skin cells. "This finding suggests that adult stem cells primarily regenerate the tissue in which they normally reside, with little plasticity to regenerate other tissues," De Luca says. "This calls into question the supposed plasticity of adult stem cells and highlights the need to carefully chose the right type of stem cell for therapeutic tissue regeneration."
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Stem Cell Reports, De Rosa et al.: "LONG-TERM STABILITY AND SAFETY OF TRANSGENIC CULTURED EPIDERMAL STEM CELLS IN GENE THERAPY OF JUNCTIONAL EPIDERMOLYSIS BULLOSA."
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Gene therapy for human skin disease produces long-term benefits
