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Compensation for Human Eggs Approved by Key California Senate Committee, But Not For CIRM Researchers

Posted: June 16, 2013 at 2:58 am

Legislation that would permit women in
California to be paid for their eggs for scientific research
yesterday cleared a key state Senate committee and is likely headed
for the governor's desk.
The measure by Assemblywoman Susan
Bonilla,
D-Concord, was approved on a 6-1 vote by the Senate Health
Committee
and now goes to the Senate floor. Earlier, it passed the
Assembly on a 54-20 vote.
Some stem cell researchers and other
scientists have chafed under state restrictions that bar compensation
for eggs while that the same time fertility clinics are paying an average of $9,000 a session for eggs, with some prices going as high as $50,000.
However, the legislation will not
affect researchers using grants from the $3 billion California stem
cell agency. The agency's regulations bar compensation for eggs in
the research that it funds. That means that at least a two-tiered
research system would exist in California not to mention another tier
created by federal regulations that differ from both those of the
stem cell agency and those set by the legislation.
CIRM's restrictions are required by
Proposition 71, which created the agency in 2004, and cannot be
changed without a 70 percent vote of the legislature. Bonilla's bill
requires only a majority vote.
Bonilla's legislation is sponsored by
American Society for Reproductive Medicine, the chief industry
group for the largely unregulated fertility industry.
The analysis prepared for yesterday's
committee session summarized Bonilla's arguments for the measure in
this fashion:

“This bill seeks to create equity in
the field of medical research compensation by removing the
prohibition on compensation for women participating in oocyte (egg)
donation for medical research. All other research subjects are
compensated for their time, trouble, and inconvenience involved in
participating in research. AB 926 ensures that women are treated
equally to all other research subjects - allowing them to actively
evaluate their participation in research studies. Unfortunately, the
ban on compensation has had serious unintended consequences. It has
led to a de facto prohibition on women’s reproductive research in
California, adversely impacting the same women that the ban intended
to protect. With few oocytes donated, fertility research and
fertility preservation research has been at a standstill. This
greatly affects women suffering from fertility issues and women
facing cancer who would like to preserve their oocytes.”

A number of organizations are opposed
to the bill including the Center for Genetics and Society in Berkeley
and the Catholic Church. The bill analysis summarized some of the
opposition arguments in this fashion:

“Egg harvesting exposes healthy young
women to multiple synthetic hormones in order to produce many times
the normal number of eggs per cycle. One of the potential harms is
OHSS, which has resulted in hospitalizations and at least a few
documented deaths. These groups state that many experts remain
concerned about the long-term risks of these drugs, especially
their potential impact on infertility and various cancers.
Follow-up research on egg providers, which could establish the
frequency and severity of these adverse outcomes, is widely
recognized to be grossly inadequate.”

In addition to risk and religious
objections, opponents also argue that poor and minority women are
likely to be exploited by enterprises seeking their eggs to resell at
a profit.
No major stem cell research
organizations, including the California stem cell agency, have taken
a position on the bill. The legislation has received little public
attention, although The Sacramento Bee carried an article last March.
Ruha Benjamin, author of "People's Science" and assistant professor at Boston
University
, also wrote about the measure in April on the Huffington
Post
. Benjamin said,
UC Berkeley professor Charis
Thompson
 compares egg
donation to 'other kinds of physically demanding service work,'
arguing for a 'salary negotiation between the state agency (or
relevant employer) and the donor.' This, she contends, is a 'sensible
and dignified recognition of [the donor's] work, time, and effort.'
And instead of refusing compensation to women, Thompson suggests that
we 'direct our efforts to understanding and minimizing' the risks.
“Indeed. Now more than ever, we must
redouble our efforts, because the market in eggs appears to be
expanding from private reproduction to public research, and
increasingly overseas, if the surrogacy
industry
 is any indication of how 'cheaper' women become a
reserve army of bio-labor in less regulated regions.” 

Source:
http://feedproxy.google.com/~r/blogspot/uqpFc/~3/SVuriAz87l0/compensation-for-human-eggs-approved-by.html

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Merksamer Makes Only Bid For Stem Cell Agency Lobbying Contract

Posted: June 16, 2013 at 2:58 am

Only one of California's lobbying firms
is interested in working for the California stem cell agency – at
least interested enough to put in a bid.
However, that is likely more of a
function of the small size of the contract – $65,000 – and the
entrenched nature of CIRM's existing lobbyist – Nielsen, Merksamer,
Parrinello, Gross & Leoni LLP
– one of the state Capitol's
larger lobbying firms with $5 million in billings last year.
The firm touted its longstanding
connection to the $3 billion agency in its 21-page proposal in
response to a CIRM RFA this spring. The firm has been with CIRM since
2005.
Nielsen Merksamer's proposal also noted
a couple of other interesting aspects of the continuing arrangement.
CIRM will run out of money for new grants in 2017, and Nielsen
Merkasamer said,

“Furthermore, as a premier
legislative advocacy and (Nielsen's italics) ballot measure
law ?rm, Nielsen Merksamer can actively and effectively assist CIRM
as it contemplates returning to the voters for additional funding.”

The proposal also suggested that it can
conceal information that normally would be public record. The firm
said,

“Another unique advantage offered by
Nielsen Merksamer is that, unlike the vast majority of lobbying ?rms,
since we are a full-service law ?rm, our relationships with our
clients are subject to the attorney-client privilege.”

CIRM used such a technique in 2012 and 2008 in matters involving its budget and PR advice.
Nielsen Merksamer also said,

“(N)o one understands CIRM’s 'total
picture' better than Nielsen Merksamer. Not only has Nielsen
Merksamer been representing CIRM before the Legislature for the past
decade, but Nielsen Merksamer was also one of the principal drafters
of the aforementioned Proposition 71—which brought CIRM to life.
The depth of Nielsen Merksamer’s familiarity with, and
understanding of, CIRM’s mission and structure, the challenges it
faces, and the promise it holds simply cannot be matched by any other
legislative advocate.”

The firm said it would not need the
$65,000 offered by CIRM but would charge only $49,200 annually, about the same as
it has been paid for several years. Steve Merksamer and Gene Erbin,
who drafted portions of Proposition 71, would handle most of CIRM's
affairs. John Moffatt and Missy Johnson would also be available.
The firm's proposal outlined several
instances where it successfully killed legislation opposed by CIRM.
You can read about them in their proposal below.

Source:
http://feedproxy.google.com/~r/blogspot/uqpFc/~3/kTRN6kUuSDk/merksamer-makes-only-bid-for-stem-cell.html

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Jeunesse Global on Stem Cells and Anti Aging – Video

Posted: June 15, 2013 at 4:50 am


Jeunesse Global on Stem Cells and Anti Aging

By: Jbizbeauty Chan

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Jeunesse Global on Stem Cells and Anti Aging - Video

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Stem Cells May Be Secret to Regenerating Fingers and Toes

Posted: June 15, 2013 at 4:50 am

Mammals can regenerate the very tips of their fingers and toes after amputation, and now new research shows how stem cells in the nail play a role in that process.

A study in mice, detailed online today (June 12) in the journal Nature, reveals the chemical signal that triggers stem cells to develop into new nail tissue, and also attracts nerves that promote nail and bone regeneration.

The findings suggest nail stem cells could be used to develop new treatments for amputees, the researchers said. [Inside Life Science: Once Upon a Stem Cell]

In mice and people, regenerating an amputated finger or toe involves regrowing the nail. But whether the amputated portion of the digit can regrow depends on exactly where the amputation occurs: If the stem cells beneath the nail are amputated along with the digit, no regrowth occurs, but if the stem cells remain, regrowth is possible.

To understand why these stem cells are crucial to regeneration, researchers turned to mice. The scientists conducted toe amputations in two groups of mice: one group of normal mice, and one group that was treated with a drug that made them unable to make the signals for new nail cells to develop.

They found that the signals that guided the stem cells' development into nail cells were vital to regenerating amputated digits. By five weeks after amputation, the normal mice had regenerated their toe and toenail. But the mice that lacked the nail signal failed to regrow either their nails or the toe bone itself, because the stem cells lacked the signals that promote nail-cell development. When the researchers replenished these signals, the toes regenerated successfully.

In another experiment, the researchers surgically removed nerves from the mice toes before amputating them. This significantly impaired nail-cell regeneration, similar to what happened to the mice that lacked the signals to produce new nails. Moreover, the nerve removal decreased the levels of certain proteins that promote tissue growth.

Together, the results show that nail stem cells are critical for regrowing a lost digit in mice. If the same turns out to be true in humans, the findings could lead to better treatments for amputees.

Other animals, including amphibians, can also regenerate lost limbs. For example, aquatic salamanders can regrow complete limbs or even parts of their heart a process that involves cells in their immune system. By studying these phenomena in other animals, it may be possible to enhance regenerative potential in people, the researchers said.

Follow Tanya Lewis on Twitterand Google+.Follow us @livescience, Facebook& Google+. Original article onLiveScience.com.

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Stem Cells May Help Some With Avascular Necrosis (AVN)

Posted: June 15, 2013 at 4:50 am

TAMPA, Fla., June 14, 2013 /PRNewswire/ --Stem cells have long been touted as the next big thing. Well just maybe, it is here. According to Dr. Dennis Lox, some patients with a disorder of the bone called avascular necrosis (AVN), have turned to stem cell therapy for aid. Avascular necrosis (AVN) also referred to as osteonecrosis or ischemic necrosis, is a condition in which the blood supply to the bone becomes disrupted, leading that region of bone to die. This is referred to as necrosis. The region may be very painful, and the region of necrosis may collapse resulting in severe arthritis. This has led to numerous joint replacement surgeries. It is estimated that 20,000 new cases a year of AVN, are diagnosed in the United States. AVN commonly occurs in the hip, shoulder, knee, ankle, and can even be present in multiple joints at the same time. http://www.drlox.com

Dr. Dennis Lox, http://www.drlox.com a Regenerative and Sports Medicine physician in the Tampa Bay, Florida area, comments that regenerative therapies such as Platelet Rich Plasma (PRP) and Stem Cell Therapy, are being used to treat avascular necrosis. Dr. Lox reports that what previously was a career ending injury for athletes like Bo Jackson, may not be so today if treated early. Preventing the secondary arthritis in AVN may save the joint. Also, Dr. Lox stresses, it is possible that the lost blood supply can be repaired, and stem cells have healed areas of bone necrosis.

AVN may be caused by many factors. Trauma is a frequent precipitating event. It also may be seen in some medical conditions, especially those that impair blood flow, such as embolism and thrombosis (blood clots). AVN also is seen with greater frequency with prolonged high corticosteroid usage.

Dr. Lox reports, he has treated almost every joint that gets AVN successfully with stem cells, including athletes in many different sports. He states it is imperative to get early treatment, and thoroughly evaluate each patient individually for optimal treatment decisions.

For more information Dr. Dennis Lox may be reached at (727) 462-5582 or visit http://www.drlox.com.

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Stem Cells May Help Some With Avascular Necrosis (AVN)

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Pastor Chui Depending on Source, Stem Cells Can Kill or Heal – Video

Posted: June 14, 2013 at 8:41 pm


Pastor Chui Depending on Source, Stem Cells Can Kill or Heal
This is a 13-minute sermon from science. It describes why adult stem cells heal and embryonic stem cells destroy life in them. Adult stem cells have more pro...

By: Christopher Chui

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Pastor Chui Depending on Source, Stem Cells Can Kill or Heal - Video

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NIANZHEN LI ON: ISSCR 2013 Poster T2186 "Differentiation of Human Induced Pluripotent Stem Cells…" – Video

Posted: June 14, 2013 at 8:41 pm


NIANZHEN LI ON: ISSCR 2013 Poster T2186 "Differentiation of Human Induced Pluripotent Stem Cells..."
Fluidigm Senior Scientist, Nianzhen Li shares her scientific abstract for ISSCR. The poster #T-2186 is titled: "Differentiation of Human Induced Pluripotent...

By: fluidigm

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Nanofibers and electrospinning of stem cells for osteoarthritis treatment – Video

Posted: June 14, 2013 at 8:41 pm


Nanofibers and electrospinning of stem cells for osteoarthritis treatment
http://www.stemcellsarthritistreatment.com Spiro writing for the Johns Hopkins University reported on a study that showed a spun 3-D scaffold of nanofibers coated with stem cells did a better...

By: Nathan Wei

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Nanofibers and electrospinning of stem cells for osteoarthritis treatment - Video

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NIANZHEN LI ON: ISSCR 2013 Poster T2186 “Differentiation of Human Induced Pluripotent Stem Cells…” – Video

Posted: June 14, 2013 at 12:49 am


NIANZHEN LI ON: ISSCR 2013 Poster T2186 "Differentiation of Human Induced Pluripotent Stem Cells..."
Fluidigm Senior Scientist, Nianzhen Li shares her scientific abstract for ISSCR. The poster #T-2186 is titled: "Differentiation of Human Induced Pluripotent...

By: fluidigm

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NIANZHEN LI ON: ISSCR 2013 Poster T2186 "Differentiation of Human Induced Pluripotent Stem Cells..." - Video

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Life Technologies Launches Tests for Gauging Effectiveness of Stem Cells for Lab Use

Posted: June 14, 2013 at 12:49 am

San Diegos Life Technologies Corp. has launched a series of tests developed with Harvard University researchers that gauge whether stem cells are able to perform in a lab setting and transform into other kinds of cells.

This comes three months after the partnership between the university and San Diegos largest biotech was announced. As more and more scientists begin using stem cells in their research, they are looking for ways to make the process more efficient and inexpensive, the company said.

The test, called the TaqMan hPSC Scorecard, will be offered with cloud-based software for rapid data analysis and data sharing among researchers, the company said.

The rapid advancements in stem cell research over the last few years have created a need for more effective and standardized methods for characterizing pluripotent cells, said Alex Meissner, lead researcher in the project at Harvard University, in a statement. Today, the field of genomics is helping to meet that demand through development of novel approaches that can help deliver the promise of stem cells.

Indeed, the global stem cell characterization field is considered a growing segment in the $1 billion stem cell research tools market, according to a recent report from Arlington-based life sciences market research firm Bioinformatics LLC. The segment is currently valued at about $30 million a year.

SDBJ Staff Report

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Life Technologies Launches Tests for Gauging Effectiveness of Stem Cells for Lab Use

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