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Sacramento Bee: Ongoing Conflict Problems No Help for Future Funding of Stem Cell Agency

Posted: June 2, 2013 at 3:07 am

The Sacramento Bee says conflict of
interest problems continue to trouble the California stem cell agency
despite its assertions that it has “turned a page” on the issues.
In an editorial Saturday, The Bee said
that CIRM Chairman Jonathan Thomas “has vowed to be aggressive in
avoiding conflicts in dispersing millions of public dollars for stem
cell research. Yet serious conflicts continue to be
revealed involving CIRM.”
The Bee cited articles on the
California Stem Cell Report earlier this month about a $21,630 gift
by its former chairman, Robert Klein, and the employment by Klein of
Vice Chairman Art Torres. The Bee said the situation “throws
into question a $20 million grant awarded last year to StemCells
Inc.
, a company that wants to transplant neural stem
cells to treat Alzheimer's
disease.” (See herehere and here)
The Bee also cited the case of Lee
Hood
, an internationally renown scientist who violated the agency's conflict of interest policy. Hood failed to disclose to CIRM a
conflict involving an application that he was reviewing on behalf of
the agency. The Bee said the agency's failure to detect the conflict
was “serious oversight."
Eight readers commented on the
editorial and agency, generally unfavorably about CIRM.
But reader “bchild” said,

“It took a couple years for them to start funding projects and it may take years to see results. Wall
Street got 1.5 trillion and the promise of 10x that if they get
into trouble again, the scientists (and their business buds) just
want a couple billion...In the end who do you trust more with
public money? At least there is the appearance of public benefit
here..."

The Bee concluded,

“None of this helps CIRM's reputation
in being fair and impartial in spending $3 billion in public funds.
It surely won't help the institute's standing with the Legislature
and the public, should it need help staying in operation when its
funding is exhausted in a few years.”

The editorial was also carried by at least one other paper in the McClatchy chain.

Source:
http://feedproxy.google.com/~r/blogspot/uqpFc/~3/BZeSccFCbBU/sacramento-bee-ongoing-conflict.html

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Embryonic Stem Cells Science Project 5 minutes version – Video

Posted: June 1, 2013 at 9:43 pm


Embryonic Stem Cells Science Project 5 minutes version
Areeb Siddiqui Naman Garg.

By: Areeb Siddiqui

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Embryonic Stem Cells Science Project 5 minutes version - Video

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A Different View on Bone Marrow Stem Cells – Video

Posted: June 1, 2013 at 9:41 am


A Different View on Bone Marrow Stem Cells
HSCI Principal Faculty member Les E. Silberstein, MD, details how new imaging technologies allowed his laboratory to discover that bone marrow stem cells are located near blood vessels, but...

By: harvardstemcell

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A Different View on Bone Marrow Stem Cells - Video

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High Anal Fistula Cure Using Stem Cells Therapy @ StemRx India – Video

Posted: June 1, 2013 at 9:41 am


High Anal Fistula Cure Using Stem Cells Therapy @ StemRx India
Anal fistula is a chronic phase of anorectal sepsis and is characterized by chronic purulent discharge or cyclical pain associated with abscess formation, followed by intermittent spontaneous...

By: StemRx BioScience

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High Anal Fistula Cure Using Stem Cells Therapy @ StemRx India - Video

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Alzheimer’s Stem Cell Research: Ask the Expert – Larry Goldstein UCSD – Video

Posted: June 1, 2013 at 9:41 am


Alzheimer #39;s Stem Cell Research: Ask the Expert - Larry Goldstein UCSD
Visit: http://www.uctv.tv/) In this first installment of CIRM TV #39;s "Ask the Expert" video series, Larry Goldstein of the University of California, San Diego...

By: UCtelevision

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Alzheimer's Stem Cell Research: Ask the Expert - Larry Goldstein UCSD - Video

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How good to use home pregnancy tests

Posted: June 1, 2013 at 2:54 am

Home pregnancy tests have been practiced for long by women and is quite trusted way of confirming your doubts when it comes to conceiving. Here are certain signs that can tell you that you are probably pregnant.

If you have missed your period or you are having an abnormal or unusual period may be you are pregnant. If you have got frequent urinating tendencies or you throw up (vomit) again and again it is possible that you are pregnant. Generally women tend to lose their control over bladder when pregnant; it is very hard to control excretion of urine. Morning sickness or nausea is a tendency that is observed in pregnant women. They cannot resist throwing up again and again during the second and third months of pregnancy. Enlargement or soreness in breast is also indicates that possibly you are pregnant. Breast starts to grow big and become painful. If your breast is releasing colostrums, uterus is enlarged or you are getting a lot of stretch marks there is a possibility that you may be pregnant. In case you have frequent strange cravings like you have never had in past may be a n indication that you are pregnant.

However, these are not confirmed signs of pregnancy. Some of these symptoms when experienced together increase the probability of one’s pregnancy. You should immediately rush for a pregnancy test if you are even a little doubtful. This will clarify your doubts as it is a reliable way to test your pregnancy by yourself. You can also trace the pregnancy by an ultrasound test but home pregnancy strip test is more handy, cheap and reliable.

In case you are planning to conceive these are some symptoms that might be pointing towards your positive result on a pregnancy strip. Be happy you are experiencing such phenomenon and consult a doctor as soon as possible. Apart from all this reflect on your inner sight you can feel it when you are pregnant and the tests suggested above are just a primary confirmation.

In case you do not want to bear there are ways to get out of the web. Contraceptive pills are available in the market which can be a help in forbidding any pregnancy. There are pills that you can take within 72 hours after having unprotected sex to prevent pregnancy but its intake again and again can cause side effects. If you detect a positive on the pregnancy strip, you will have to abort it whether it is by an abortion pill or by any other method.

About The Author: Camila is a writer/blogger. She loves writing, traveling and reading books. She contributes on Josh Fink

Source:
http://www.biotechblog.org/entry/good-home-pregnancy-tests/

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Bluebird bio of Massachusetts Still Waiting for California Stem Cell Money

Posted: May 31, 2013 at 6:10 pm

Seven months after the California stem
cell agency awarded $9.4 million to bluebird bio of Cambridge, Mass.,
the company has yet to receive any of the cash from the Golden State.
Kevin McCormack, a spokesman for the $3
billion agency, this week said negotiations are still underway with
the bluebird, which is planning to go public,  but did not elaborate. Post-award negotiations are
common at the agency, but generally take much less time.
The cash from CIRM is scheduled to
assist in clinical trials for a stem cell-gene therapy to correct a genetic disease in young patients with B-thalassemia, a
rare blood disorder that can cause widespread organ damage
and premature death.
Earlier this month, bluebird bio, which
prefers the lower case lettering for its name, announced that it
intends to take the company public in an $86 million offering. In
March, it announced a collaboration with Celgene that provided for an upfront payment of $75 million and promised up to $225 million per
product in potential option fees and clinical and regulatory
milestones. The CIRM grant is conditioned on a matching commitment
from bluebird.
Cash from the stem cell agency can only
be spent on operations within California. According to the CIRM summary of the review of the bluebird application, which was scored
at 73, the company said,

“We will have at least two clinical
sites in California, and more likely up to 4 sites, 2) our viral
vector manufacturing will occur in California, 3) our cell processing
will occur in California, 4) we will hire several consultants and
full-time employees within California to support the program.
Overall, several million dollars will be spent employing the services
of people, academic institutions, and other companies within the
state of California.”

The company has said that it is working
with Donald Kohn at UCLA and Elliot Vichinsky at Oakland's Children's
Hospital.
The bluebird web site lists a
California location for bluebird at 1001 Bayhill Dr, Suite 200, in
San Bruno, which is south of San Francisco. An Internet search
indicates that is a generic address for a number of business
including a realty firm, a roof repair business and a family law
attorney. The California Stem Cell Report has asked bluebird to
clarify the nature of the address.
In an interview last October with Ron Leuty of the
San Francisco Business Times, David Davidson, the lead scientist on
the project, said,

“We began the process (with CIRM)
early in (2012) but discussions have been going on for over a year
about potentially pursuing this.

“The interaction with CIRM has been
extraordinarily collaborative. We had contact with the coordinators
at CIRM that helped us manage the process. It took a lot of effort on
our part to put together a dossier providing support for our program.
It was really like a mini-regulatory filing — on the science, the
preclinical toxicology work that we’ve done, a detailed plan for
the trial, a detailed plan for the budgets, a detailed plan on how we
intended to spend the CIRM money in California. That was an important
part of it. They wanted a clear plan on how this investment would be
spent."

Source:
http://feedproxy.google.com/~r/blogspot/uqpFc/~3/zR-Ht90u_7o/bluebird-bio-of-massachusetts-still.html

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Scottish News: Stem cells blood trial licensed

Posted: May 31, 2013 at 12:46 pm

May 30 2013

The world's first human trials of synthetic blood could take place in Scotland, it has been reported.

Researchers from the Scottish Centre for Regenerative Medicine (SCRM) in Edinburgh have been granted a licence to make blood from stem cells which could be tested on humans, The Scotsman has reported.

The licence from the UK's Medicines and Healthcare products Regulatory Agency will allow scientists at SCRM to attempt to manufacture blood on an industrial scale which will help to tackle shortages and stop the transfer of infections from blood donors, according to the paper.

Trials on humans, if approved, would be the first stage in establishing more large-scale clinical trials and could result in regular use of synthetic blood.

Researchers will use stem cells from adult donors - known as induced pluripotent stem cells - as part of this project instead of the more controversial embryotic ones.

Project leader Marc Turner said: "In the first part of the project we used human embryonic stem cell lines and one of the problems with using those lines is you can't choose what the blood group is going to be.

"Over the last few years there has been a lot of work on induced pluripotent stem cells and with those an adult can donate a small piece of skin or a blood sample and the technology allows for stem-cell lines to be derived from that sample.

"This makes our life a lot easier in some ways because that means we can identify a person with the specific blood type we want and get them to donate a sample from which we could manufacture the cell lines."

With the licence scientists will also be able to work on stem cell products used to help patients with Parkinson's disease, diabetes, cancer or those who have suffered a stroke.

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Scottish News: Stem cells blood trial licensed

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Stem Cell Therapy for Hair Loss | Hair Loss Treatment in India – Video

Posted: May 31, 2013 at 12:44 pm


Stem Cell Therapy for Hair Loss | Hair Loss Treatment in India
Stem Cell Therapy for Hair Loss - Enhances hair regrowth within 2-3 weeks after treatment!

By: AllHairSolution

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Stem Cell Therapy for Hair Loss | Hair Loss Treatment in India - Video

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Vatican Funding for California Stem Cell Agency?

Posted: May 31, 2013 at 12:33 pm

So what's with the Vatican sending cash
to the California stem cell agency? One would imagine that is an
improbable event since the agency is involved in human embryonic stem
cell research, which is an anathema to the Roman Catholic church.
However, CIRM President Alan Trounson
earlier this week disclosed the payment in an interview with Patt
Morrison
of the Los Angeles Times. He said,

“Last
year I was invited to the Vatican to
present a paper, but when I sent in a summary of what I was going to
say, they decided not to have it. They sent a check to the treasurer
of California and the treasurer rang us up and said, "What the
heck is this check from the Vatican for?" It was for the
inconvenience!”

We wanted to know a little more about
this so we queried the agency about the matter. Kevin McCormack, a
CIRM spokesman, said,

“The money was actually a wire
transfer from the Vatican to us for $453.23 and it went to CIRM's
account. It was to reimburse us for money spent on plane tickets,
etc., for Dr. Trounson to attend the Vatican conference on stem
cells.”   

Source:
http://feedproxy.google.com/~r/blogspot/uqpFc/~3/bOQKBXJGmJ8/vatican-funding-for-california-stem.html

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