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Texas biotech rounds up $2 million for platform to grow stem cells faster

Posted: February 21, 2013 at 4:47 pm

A University of Texas spinoff company has pulled in $2 million to test a new technique for culturing non-embryonic stem cells.

According to a regulatory filing, StemBioSys raised at least $2 million of a $3.5 million equity offering. A company representative was not available to elaborate, but CEO Dr. Steven Davis told the San Antonio Business Journal last year when the company began raising the round that it would fund research projects to validate the quality of the stem cells generated by the companys technology.

StemBioSys is developing XC-marrow ECM, a propriety three-dimensional culture for growing mesenchymal stem cells from bone marrow, adipose tissue and umbilical cord blood. These immature cells have multiple potential uses in research and therapeutics because they can self-renew and mature into a variety of cell types. Stem cell therapies are being studied as a repair mechanism for tissues all over the body, from the heart to the brain to the knees.

The company says its three-dimensional extracellular matrix can grow cells quicker than conventional media while retaining stem cell properties and may help overcome key obstacles in creating stem cell therapies.

The technology was developed by Dr. Xiao-Dong Chen, an associate professor of medicine at the University of Texas Health Science Center and the companys chief scientific officer, and licensed from UT.

Although its only available for research purposes now, this kind of technology could have therapeutic applications down the line. If this research transfers successfully to clinical application in humans, we could establish personal stem cell banks, Chen said back in 2011, when he and colleagues had a study published in the Journal of the Federation of American Societies for Experimental Biology. We would collect a small number of older stem cells from patients, put those into our young microenvironment to rescue them increasing their number and quality then deliver them back into the patient.

The company has struck a deal with GenCure, an affiliate of the nonprofit South Texas Blood & Tissue Center, to receive mononuclear cells from clinical grade umbilical-cord blood that it uses for R&D purposes.

It was founded in 2010 in San Antonio, Texas and has received previous funding from the Texas Technology Development Centers McDermott Pre-Seed Fund.

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Texas biotech rounds up $2 million for platform to grow stem cells faster

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Market Research Report — Therapeutic Applications of Induced Pluripotent Stem Cells Represent the Future of Medicine

Posted: February 21, 2013 at 4:47 pm

ROCKVILLE, MD--(Marketwire - Feb 21, 2013) - MarketResearch.com has announced the addition of the market research report "Complete 2012-13 Induced Pluripotent Stem Cell Industry Report" to their product offering.

iPSCs are adult stem cells that have been transformed into embryotic-like stem cells through the manipulation of gene expression and similar methods. Despite some initial concerns, induced pluripotent stem cells (iPSC) are now sold by more than half (53.4%) of U.S. research product companies and 38.7% of research product companies worldwide.

"It is clear that iPSC products are in high demand within the scientific community. Currently, it is difficult for stem cell research product suppliers, like BD BioSciences, Life Technologies, and others, to know what products iPSC scientists will demand in 2013 and beyond. The needs of scientists are constantly changing, so this market intelligence report reveals profitable opportunities for providers of iPSC research products to pursue," says BioInformant.

For the past five decades, stem cell research has provided insights to the inner workings of the body and cell regeneration. "Therapeutic applications of iPSCs represent the future of medicine," says BioInformant. The scientific community believes that one day stem cell research will assist in finding viable treatments for crippling diseases such as Parkinson's, Alzheimer's, spinal cord injuries and more.

For more information, visit http://www.marketresearch.com/land/product.asp?productid=7242167&progid=85189

Follow us on Facebook http://www.facebook.com/marketresearchdotcom Follow us on Twitter http://www.twitter.com/marketresearch_

About BioInformant WorldWide, LLC

BioInformant Worldwide, LLCis a global leader in stem cell industry data.As a specialty research company, BioInformant uses technology to track and identify profitable opportunities in stem cell product markets and provides this data to clients that prioritize industry dominance.

About MarketResearch.com

MarketResearch.com is the leading provider of global market intelligence products and services. With research reports from more than 720 top consulting and advisory firms, MarketResearch.com offers instant online access to the world's most extensive database of expert insights on global industries, companies, products, and trends. Moreover, MarketResearch.com's Research Specialists have in-depth knowledge of the publishers and the various types of reports in their respective industries and are ready to provide research assistance. For more information, call Cindy Frei at 240.747.3014 or visit http://www.marketresearch.com.

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Market Research Report -- Therapeutic Applications of Induced Pluripotent Stem Cells Represent the Future of Medicine

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SENS5 – Cellular Therapy for Intestinal Regeneration – Video

Posted: February 21, 2013 at 5:42 am


SENS5 - Cellular Therapy for Intestinal Regeneration
SENS Foundation 2011 - http://www.sens.org The Fifth SENS conference - Graca Almeida-Porada Authors E. Colletti, J. Wood, DA Ingram, ED Zanjani, M. Yoder, C. Porada, G. Almeida-Porada Wake Forest Institute for Regenerative Medicine Abnormal or inadequate vasculogenesis, local inflammation, and severe epithelial damage are common features of both inflammatory bowel disease (IBD) and radiation-induced injury resulting from pelvic or abdominal cancer treatment. Several studies have shown that adult bone marrow-derived stem cells, such as mesenchymal stem cells (MSC), upon transplantation, home to the damaged digestive tissue and facilitate mucosal repair in both IBD and radiation injury. Nevertheless, the levels of MSC intestinal engraftment are low, underscoring the need for finding ways to improve engraftment of these cells. It has also been shown that endothelial progenitor cells (EPC) exist in decreased numbers in the peripheral blood of IBD patients, which is in contrast to the presently held convention that the presence of an inflammatory state promotes the mobilization of EPC into the circulation. Furthermore, intestinal microvascular and endothelial cell dysfunction can lead to persistent tissue hypoperfusion and ischemia, further contributing to chronic inflammation. Therefore, here we investigated whether transplanted EPC can contribute to the intestinal vasculogenic process and/or the stem or mature epithelial cell pool of the intestine, and whether it is possible to ...

By: SENSFVideo

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SENS5 - Cellular Therapy for Intestinal Regeneration - Video

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Morning Skincare Routine – Video

Posted: February 21, 2013 at 5:42 am


Morning Skincare Routine
Hey guys! Hope you enjoyed this video 🙂 Products used: -Bioderma Sensibio H2O Cleanser - Crest complete Toothpaste - Colgate 360 Toothbrush - Ole Henriksen Truth Serum collagen booster - Eclos Plant Stem Cells age-defying Eye Cream -NUDE ProGenius Treatment Oil - Burt #39;s Bees Replenishing Lip Balm with Pomegranate oil - Ole Henriksen Truth Crme Advanced Hydration

By: ulayusequaluk

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Morning Skincare Routine - Video

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Brading Cancer Stem Cells: Discovery of a hot new intestinal cancer stem cell marker! – Video

Posted: February 20, 2013 at 1:47 pm


Brading Cancer Stem Cells: Discovery of a hot new intestinal cancer stem cell marker!
Excited about stem cells? Want to learn how stem cells influence cancer growth? Learn how scientists are paving the way to a better understanding of the identity and behavior of cancer stem cells! For more exciting science videos, visit Youreka Science: http://www.yourekascience.com Original article: "Dclk1 distinguishes between tumor and normal stem cells in the intestine." Nakanishi et al. Nature Genetics, Jan 2013

By: YourekaScience

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Brading Cancer Stem Cells: Discovery of a hot new intestinal cancer stem cell marker! - Video

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New Study at the Center for Regenerative Medicine – Mayo Clinic – Video

Posted: February 20, 2013 at 1:47 pm


New Study at the Center for Regenerative Medicine - Mayo Clinic
The Center for Regenerative Medicine at Mayo Clinic investigates what advances of stem cell biology would be useful to apply in the treatment of patients with end stage diseases. Jorge Rakela, MD, associate director for the Center, provides an overview of the Center which is also involved in a tissue engineering program with Arizona State University. Jeffery Cornella, MD, a gynecological surgeon at Mayo Clinic, and Johnny Yi, MD, a surgical fellow at Mayo Clinic, talk about a study underway to develop new tissue to aid in the treatment of vaginal prolapse and other conditions.

By: mayoclinic

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New Study at the Center for Regenerative Medicine - Mayo Clinic - Video

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Regenerative medicine and Stem cells Partnering Terms and Agreements

Posted: February 20, 2013 at 1:47 pm

NEW YORK, Feb. 19, 2013 /PRNewswire/ -- Reportlinker.com announces that a new market research report is available in its catalogue:

Regenerative medicine and Stem cells Partnering Terms and Agreements http://www.reportlinker.com/p01098514/Regenerative-medicine-and-Stem-cells-Partnering-Terms-and-Agreements.html#utm_source=prnewswire&utm_medium=pr&utm_campaign=Biological_Therapy

The Regenerative Medicine and Stem Cells Partnering Terms and Agreements report provides comprehensive understanding and unprecedented access to the Regenerative medicine and Stem cells partnering deals and agreements entered into by the worlds leading healthcare companies.

Trends in regenerative medicine and stem cells deals Deal terms analysis Partnering agreement structure Partnering contract documents Top deals by value Most active dealmakers Average deal terms for regenerative medicine and stem cells

The report provides a detailed understanding and analysis of how and why companies enter regenerative medicine and stem cells partnering deals. The majority of deals are development stage whereby the licensee obtains a right or an option right to license the licensors regenerative medicine and stem cells technology. These deals tend to be multicomponent, starting with collaborative R&D, and commercialization of outcomes.

This report provides details of the latest regenerative medicine and stem cells agreements including cell therapy agreements announced in the healthcare sector.

Understanding the flexibility of a prospective partner's negotiated deals terms provides critical insight into the negotiation process in terms of what you can expect to achieve during the negotiation of terms. Whilst many smaller companies will be seeking details of the payments clauses, the devil is in the detail in terms of how payments are triggered contract documents provide this insight where press releases and databases do not.

This report contains a comprehensive listing of all regenerative medicine and stem cells partnering deals announced since 2008 including financial terms where available including over 550 links to online deal records as disclosed by the deal parties. In addition, where available, records include contract documents as submitted to the Securities Exchange Commission by companies and their partners.

Contract documents provide the answers to numerous questions about a prospective partner's flexibility on a wide range of important issues, many of which will have a significant impact on each party's ability to derive value from the deal.

For example, analyzing actual company deals and agreements allows assessment of the following:

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Regenerative medicine and Stem cells Partnering Terms and Agreements

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Half-full, Half-empty Editorial on California Stem Cell Agency

Posted: February 19, 2013 at 8:18 pm

The California stem cell agency's
editorial road show paid off a bit again this week with a mildly
approving editorial in the Oakland Tribune.

The Feb.18 piece said that the presence
of Jonathan Thomas, a Los Angeles bond financier, as chairman of the
$3 billion agency has improved things, compared to the reign of Bob
Klein
, who “built a protective shield” around the agency's
governing board and prevented action to deal with obvious
conflict-of-interest problems.
The newspaper also said that “to some
extent” the agency has brought “cutting edge” scientists to the
state and helped boost the stem cell field.
That was the half-full side of the
editorial. The half-empty side included the headline.

“California
must get its stem cell house in order”

The editorial continued:

“...{T)he agency must prove that it
understands how to properly handle the public's money. …. If
the stem cell agency can establish a record as a good steward of
public dollars to finance brilliant science, it can continue to play
a useful role in stimulating and guiding research to bring the
potential cures from stem cell research to fruition.

“If it cannot do that, it will be
just another expensive Tyrannosaurus rex.”

Thomas and company are knocking on
editorial doors around the state in hopes of building support for the
board's modest – some might say inadequate – response to
recommendations for sweeping changes at the agency.  

Source:
http://feedproxy.google.com/~r/blogspot/uqpFc/~3/tMt6gs55Yvs/half-full-half-empty-editorial-on.html

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Pier Giuseppe Pelicci – IFOM-Kyoto University Joint Symposium, October 2012 – Video

Posted: February 19, 2013 at 7:46 pm


Pier Giuseppe Pelicci - IFOM-Kyoto University Joint Symposium, October 2012
Regulation of Self-Renewal in Cancer Stem Cells. Speaker affiliation: IEO - University of Milan For more info visit: http://www.ifom.eu

By: IFOMeu

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Pier Giuseppe Pelicci - IFOM-Kyoto University Joint Symposium, October 2012 - Video

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Beware…When you damage cartilage it doesn’t recover. – Video

Posted: February 19, 2013 at 7:46 pm


Beware...When you damage cartilage it doesn #39;t recover.
http://www.stemcellsarthritistreatment.com When joint cartilage is damaged, it begins to degrade and form cracks, called fibrillations. If severe enough, the cartilage damage can expose underlying bone. Why does this happen. Well... it #39;s because cartilage lacks a blood supply. It can #39;t supply stem cells from the blood or bone marrow to help with healing. Even cartilage cells-the chondrocytes- really can #39;t move to help since they #39;re trapped inside their matrix. So... bottom line, once cartilage is injured, unless something is done to provide it with cells to heal, it will continue to degrade. This is the bad news. The good news is that stem cells can repair cartilage damage when administered properly. http

By: Nathan Wei

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Beware...When you damage cartilage it doesn't recover. - Video

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