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Bioheart to Present at Cell Therapy for Cardiovascular Disease Conference in New York

Posted: January 7, 2013 at 1:44 pm

SUNRISE, Fla., Jan. 7, 2013 /PRNewswire/ --Bioheart, Inc. (BHRT.QB) will present an update on 12 years of clinical data on MyoCell for treating heart failure at the 8th Annual Conference on Cell Therapy for Cardiovascular Disease January 23-25th, 2013 @ Columbia University Medical Center - http://celltherapy.crf.org/register.html - Course Director, Warren Sherman, M.D.

(Logo: http://photos.prnewswire.com/prnh/20130107/FL37699LOGO )

Howard J. Leonhardt, Founder and Chief Technology Officer of Bioheart, will present data from clinical trials sponsored by the company since 2001.

In Phase II/III clinical trials stage in the U.S. for muscle stem cells for treating advanced heart failure, Bioheart's MyoCell is believed to be the only cell type able to create new contractile muscle in heart scar tissue.Phase II/III Part I interim results demonstrated 95.7 meters improvement in exercise capacity in Bioheart MyoCell patients over placebo (-4 meters) in a double blind randomized study.This compares to -4 meters for CHF drugs, 16 meters for CRT pacers, 53 meters for cardiac stem cells, 52 meters for adipose derived cells and 10 meters allogeneic bone marrow derived cells.

Leonhardt will also provide a look at new generation improvements brought forward to enhance cell transplantation by Bioheart which include:SDF-1 gene transfection, electrical stimulation see http://www.myostimpacers.com, repeat injections, and nutrient hydrogel.

Founded in 1999, Bioheart is one of the original cell therapy companies.Since that time, more than 400 heart failure patients have been enrolled in various myoblast therapy clinical trials worldwide. 84% percent of Bioheart MyoCell treated patients have improved while only 16% have worsened. In placebo and control groups 69% of patients have worsened.

130 more patients are needed to complete the randomized, double blinded, placebo controlled MARVEL trial.MyoCell is a muscle-derived stem cell therapy designed to populate regions of scar tissue within a patient's heart with new living cells for the intended purpose of improving cardiac function and quality of life in chronic heart failure patients.

About Bioheart, Inc.

Bioheart is committed to maintaining its leading position within the cardiovascular sector of the cell technology industry delivering cell therapies and biologics that help address congestive heart failure, lower limb ischemia, chronic heart ischemia, acute myocardial infarctions and other issues. Bioheart's goals are to cause damaged tissue to be regenerated, when possible, and to improve a patient's quality of life and reduce health care costs and hospitalizations.

Specific to biotechnology, Bioheart is focused on the discovery, development and, subject to regulatory approval, commercialization of autologous cell therapies for the treatment of chronic and acute heart damage and peripheral vascular disease. Its leading product, MyoCell, is a clinical muscle-derived cell therapy designed to populate regions of scar tissue within a patient's heart with new living cells for the purpose of improving cardiac function in chronic heart failure patients. For more information on Bioheart, visit http://www.bioheartinc.com, or visit us on Facebook: Bioheart and Twitter @BioheartInc.

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Bioheart to Present at Cell Therapy for Cardiovascular Disease Conference in New York

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Stem Cell Treatment for Dementia – procedure angiograms – Video

Posted: January 7, 2013 at 7:41 am


Stem Cell Treatment for Dementia - procedure angiograms
Dye is injected into cerebral circulation prior to the implantation of the patient #39;s own adult stem cells to show the area and amount of circulation. Then, following the treatment, another injection of dye is made to see if there has been any change in circulation. The change is startling, showing significant improvement in volume and vasculature.

By: mrcalcat

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Stem Cell Treatment for Dementia - procedure angiograms - Video

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Gene Therapies Will Cure Many a Disease (preview)

Posted: January 6, 2013 at 7:04 pm

The Science Of The Next 150 Years: 50 Years in the Future [More]



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Cell Therapy Blog welcomes 2013

Posted: January 6, 2013 at 8:04 am


Happy new year to all our readers.  We look forward to our interactions throughout 2013. This month watch for:
We look forward to seeing you on the 2013 conference circuit.  For a complete and current list of 2013 cell therapy industry conferences, click here.

We will be in San Francisco next week during EBD Biotech Showcase and JP Morgan as well as at the Phacilitate Cell and Gene Therapy Forum in Washington, DC at the end of the month.

As always we welcome your comments, feedback, criticisms, and questions.

Thank you for all for everything to contributed to and did to support this blog and our efforts this past year.  Let's have a great 2013!


p.s.  Don't forget to follow Cell Therapy Blog on Twitter @celltherapyblog 

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Cancer-Killing Stem Cells Could Be Used To Treat Cancer

Posted: January 6, 2013 at 1:46 am

Featured Article Academic Journal Main Category: Stem Cell Research Also Included In: Immune System / Vaccines;Cancer / Oncology Article Date: 05 Jan 2013 - 0:00 PST

Current ratings for: Cancer-Killing Stem Cells Could Be Used To Treat Cancer

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The researchers, from the RIKEN Research Centre for Allergy and Immunology in Yokohama, describe how they created cancer-specific killer T lymphocytes from iPSCs, in a paper published online on 3 January in the journal Cell Stem Cell.

Hiroshi Kawamoto and colleagues started with mature T lymphocytes specific for a certain type of skin cancer and reprogrammed them into IPSCs with the help of "Yamanaka factors". The iPSCs cells then generated fully active, cancer-specific T lymphocytes.

Yamanaka factors are named after Shinya Yamanaka, who with British scientist John B. Gurdon, won the 2012 Nobel Prize for Physiology or Medicine for discovering that mature cells can be reprogrammed to become pluripotent stem cells.

Yamanaka discovered that treating adult skin cells with four pieces of DNA (the Yamanaka factors) makes them revert back to their pluripotent state, where they have the potential, almost like embryonic stem cells, to become virtually any cell in the body.

"We have succeeded in the expansion of antigen-specific T cells by making iPS cells and differentiating them back into functional T cells."

Previous attempts using conventional methods to make cancer-killing T lymphocytes in the lab have not been very successful. The cells failed to kill the cancer cells, mainly because they did not live long enough.

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Cancer-Killing Stem Cells Could Be Used To Treat Cancer

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Stem Cell Therapy for Autism, Mumbai, India – Video

Posted: January 6, 2013 at 1:45 am


Stem Cell Therapy for Autism, Mumbai, India

By: Rajeev Ranjan

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Stem Cell Therapy for Autism, Mumbai, India - Video

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knee replacements soaring – Video

Posted: January 6, 2013 at 12:41 am


knee replacements soaring
Knee Replacements On The Rise Among Seniors Janice Lloyd writing in USA Today reported on a study published in the Journal of the American Medical Association, which found that the "number of total knee replacement surgeries has soared 161.5% among Medicare participants over the past 20 years, a $5 billion annual tab that will continue to grow as the USA #39;s 77 million Baby Boomers age." The article says that "the wider use of knee replacement, on one hand, is good news for the rapidly aging population." However, it adds that although "knee surgery eases pain from severe arthritis and improves quality of life," the study authors say the improvements "can be viewed as another strain on government, individuals, and businesses struggling with unremitting growth in health care costs." There #39;s got to be a better way. I still advocate stem cells.

By: Nathan Wei

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knee replacements soaring - Video

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Carlson second part – blood stem cells – Video

Posted: January 6, 2013 at 12:41 am


Carlson second part - blood stem cells
The saga of Carlson 13, the old champion considered clinically irrecoverable, continues. You remember him thin, with scars from the burning and the ultra sound of that tendon lesion that didn #39;t want to heal? You then saw him taking part in his first competitions in December 2011. Today, a year later, how is he? He #39;s totally recovered? You be the judge! Over the year the horse has taken part in many competitions always performing well up to one metre fifty but in November, with my 20 year old daughter Antonia, who this year has taken 8 university exams, he competed in the Celye World Cup one metre sixty competition with only one error. After two weeks Carlson and Antonia reached the fourth place in the Italian Master Memorial Dalla Chiesa, the most important Italian indoor event, with 2 manche without errors where the nearly 17 year old champion made fun of the heights by jumping with a fantastic technique. What #39;s more he did this barefoot. How could this have happened? The blood stem cells that I use in my treatment played a large role. Be aware that stem cells are not a therapeutic protocol in themselves, but are part of the protocol and the better the protocol the better they function. In the scientific work of Dr. Y.Kasashima thoroughbred race horses that had been given bone marrow adult stem cells gave the same performances in competitions 2 years later as did untreated horses left to rest for the same period, even though there was a histological improvement in the ...

By: marcopolettinieng

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Carlson second part - blood stem cells - Video

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MIRRORED Growing Body Parts.mp4 – Video

Posted: January 6, 2013 at 12:40 am


MIRRORED Growing Body Parts.mp4
This is an older 60 minutes show that speaks of growing new body parts through stem cells. Dr. Atala, mentioned in the beginning of this video completed a study to regrow a rabbits penis after being completely severed. This same rabbit successfully sired bunnies after the new grown penis was completed. Could this be a viable option for Peyronie #39;s disease patients?

By: Peyronieschannel

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MIRRORED Growing Body Parts.mp4 - Video

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Diamond Before and 30 days after stem cells Treatment for FX. Sesimoid

Posted: January 6, 2013 at 12:40 am


Diamond Before and 30 days after stem cells Treatment for FX. Sesimoid Suspensory Desmitis
Photos before are in clinic are on concrete artificial light The photos 30 days post injection are in natural light on rock surface

By: WichitaEquine

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Diamond Before and 30 days after stem cells Treatment for FX. Sesimoid

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