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San Diego Newspaper Calls for Major Changes at California Stem Cell Agency

Posted: December 21, 2012 at 3:46 pm

The San Diego U-T today ran an
editorial that was headlined “Stem cell research institute must fix itself.”

The editorial was written in response
to findings by the Institute of Medicine that the $3 billion
California stem cell should make sweeping changes to deal with issues
ranging from conflicts of interest to management structure.
The San Diego U-T editorial came as part of
a unanimous reaction so far from California newspapers.
The San Diego paper said,

“We hope we
are wrong in thinking that, given the number of times the same
criticisms of CIRM have come up over the past seven years, the agency
doesn’t really take them seriously.

“If that is
the agency’s attitude, it could well be a fatal error. CIRM has
enough money remaining from the original $3 billion to continue
awarding research grants for another four years. But it will either
have to go back to California voters in 2014 or 2016 for another bond
issue to continue its operations or find a different source of
funding.

“Whichever
CIRM decides, whoever is asked to foot the bill, either taxpayers or
the private sector will demand transparency and accountability. We
hope CIRM can demonstrate it.”

Source:
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Boxing in the California Stem Cell Board

Posted: December 21, 2012 at 3:13 pm

Robert Klein is much admired for his
prodigious efforts on behalf of stem cell research, including his
service as the first chairman of the $3 billion California stem cell
agency.

Klein was adept at many tasks, such as
directing the ballot campaign that resulted in passage of Proposition
71
in 2004 and creation of of the agency. One of Klein's less
publicly recognized skills was putting the governing board of the
agency in a box from time to time.
The 29 members of that board could well
be headed for another box – this time in connection with their
position on the Institute of Medicine's sweeping recommendations for major changes at the stem cell agency.
Here is how that could work based on a
similar situation in 2009 involving Klein and the Little Hoover
Commission
, the state's good government agency.
Klein did not welcome the inquiry by
the commission, which was requested by state lawmakers who had butted
heads with Klein. He knew that the commission would come up with
recommendations that he would find odious.
So even before the Hoover report was
released in its final form, Klein had the board's outside counsel,
James Harrison, prepare a legal memo on a draft version of the study.
Harrison's memo said many of the most far-reaching recommendations of
the commission would require a vote of the people – a more costly
and unlikely proposition than a vote of the legislature.
Harrison's memo was dated June 23,
2009. The commission report was released June 26, 2009. On June 30, 2009, Klein warned directors in an email that support of some of the
proposals would violate their oath of office. The first time a
subcommittee of directors had to a chance to react publicly came on
July 16, 2009. The full board did not have the Hoover report on its
agenda until Aug. 6, 2009. By that time, they were thoroughly boxed
in.
Their choices were minimal, even if
they disagreed with Klein. To do anything other than go along with
him would mean rejection of a 10-page legal opinion from Harrison,
which could be interpreted as no-confidence vote on Harrison and
possibly Klein. Board members were not interested in losing
Harrison, who has been valuable asset to the board since day one.
Overthrowing Klein was even less likely in 2009.
Harrison is currently revisiting his
2009 memo in the wake of the Institute of Medicine recommendations,
which echo some of the major Hoover proposals. The board has also
scheduled a workshop for Jan. 23 that will discuss the IOM proposals.
If Harrison produces another legal memo
that is as explicit as the 2009 document, CIRM directors will have
few choices.  The best procedure may well be for Harrison
to continue his work on the memo until after the Jan. 23 meeting.
Directors could then decide on initial steps in connection with the
IOM recommendations and ask Harrison how they can proceed legally, although the task is really more of a political challenge than a legal
one.
Directors paid $700,000 for the IOM's evaluation and advice. It is a prestigious body with virtually no critics in the scientific community. It would be odd, to say the least, for CIRM directors to now reject major recommendations from the blue-ribbon panel only because the proposals might require a statewide vote. The response is likely to be from some: Well, stem cell directors, let's have a statewide vote, and we expect you to support the IOM changes if you plan to seek additional state funding. 
Placing another stem cell measure on the ballot -- with or without related additional funding for the agency -- would bring into play a host of issues, including possible elimination of the agency. Not to mention disturbing existing stakeholder relationships and raising uncertainty in the scientific and biotech business communities. 
Directors believe the agency has made a major contribution both to California and to science. So does the IOM. The directors need to move forward on the IOM recommendations if they are to continue their research efforts beyond 2017, when cash for new grants runs out.  And putting the board in a box is not the best way to give them the room they need to maneuver. 

Source:
http://feedproxy.google.com/~r/blogspot/uqpFc/~3/Dh4v5HREt6Y/boxing-in-california-stem-cell-board.html

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Michael Zdanowski of National Cord Blood on public banking – at World Cord Blood Congress 2012 – Video

Posted: December 21, 2012 at 9:43 am


Michael Zdanowski of National Cord Blood on public banking - at World Cord Blood Congress 2012
Michael Zdanowski, Director of Operations at National Cord Blood, spoke at the World Cord Blood Congress 2012 on the topic, #39;Self-sustainability for public banking: short and long term perspectives. #39; World Cord Blood Congress is where private and public cord blood banks, pharma and biotechs, academia and government come to debate advances in cord blood banking and therapeutics. For more information, go to http://www.terrapinn.com/cordblood. Or, check out our blog at blogs.terrapinn.com/total-biopharma for up to date information on the stem cells, RM and cord blood banking and therapeutics sectors.From:biopharmachannelViews:0 0ratingsTime:25:08More inScience Technology

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Michael Zdanowski of National Cord Blood on public banking - at World Cord Blood Congress 2012 - Video

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Dean Tozer of Shire Regenerative Medicine – at Stem Cells USA

Posted: December 21, 2012 at 9:43 am


Dean Tozer of Shire Regenerative Medicine - at Stem Cells USA Regenerative Medicine Congress 2012
Dean Tozer, Senior Vice President of Corporate Development at Shire Regenerative Medicine, spoke at the Stem Cells USA Regenerative Medicine Congress 2012 on the topic, #39;Going all-in: Shire #39;s $750M bet on Shire Regenerative Medicine. #39; The Stem Cells Regenerative Medicine Congress is where pharma, biotech, academia, government and investors come to uncover the technologies, strategies and business models that will help get stem cell and regenerative medicine treatments to market faster and more cost effectively. For more information, go to http://www.terrapinn.com/stemcellsusa. Or, check out our blog at blogs.terrapinn.com/total-biopharma for up to date information on the stem cells, RM and cord blood banking and therapeutics sectors.From:biopharmachannelViews:0 0ratingsTime:18:23More inScience Technology

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Using Stem Cells to Study Autism – Video

Posted: December 21, 2012 at 9:43 am


Using Stem Cells to Study Autism
(Visit: http://www.uctv.tv Dr. Dolmetsch #39;s group has developed methods for using induced pluripotent stem cells to study human brain development and for identifying cell and molecular phenotypes associated with disease. His laboratory has also made significant contributions to calcium signaling including the identification of signaling pathways that connect calcium channels to gene activation and the identification of the mechanisms of activation of store operated calcium channels. The lab has also developed several new technologies to study cell signaling including enzyme complementation systems to measure protein interactions in cells and light-activated signaling proteins to control biochemical cascades. Series: "MIND Institute Lecture Series on Neurodevelopmental Disorders" [Health and Medicine] [Show ID: 24425]From:UCtelevisionViews:4 2ratingsTime:01:12:41More inEducation

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William Prather of Pluristem on treating Aplastic Anemia with stem cells – at Stem Cells USA 2012 – Video

Posted: December 21, 2012 at 9:43 am


William Prather of Pluristem on treating Aplastic Anemia with stem cells - at Stem Cells USA 2012
William Prather, Sr. VP Corporate Development at Pluristem, spoke at the Stem Cells USA Regenerative Medicine Congress 2012 on the topic, #39;Treating Aplastic Anemia with PLX Stem Cells. #39; The Stem Cells Regenerative Medicine Congress is where pharma, biotech, academia, government and investors come to uncover the technologies, strategies and business models that will help get stem cell and regenerative medicine treatments to market faster and more cost effectively. For more information, go to http://www.terrapinn.com/stemcellsusa. Or, check out our blog at blogs.terrapinn.com/total-biopharma for up to date information on the stem cells, RM and cord blood banking and therapeutics sectors.From:biopharmachannelViews:0 0ratingsTime:21:02More inScience Technology

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William Prather of Pluristem on treating Aplastic Anemia with stem cells - at Stem Cells USA 2012 - Video

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Edward Lanphier of Sangamo on engineering genetic cures – at Stem Cells USA

Posted: December 21, 2012 at 9:43 am


Edward Lanphier of Sangamo on engineering genetic cures - at Stem Cells USA RM Congress 2012
Edward Lanphier, CEO of Sangamo, spoke at the Stem Cells USA Regenerative Medicine Congress 2012 on the topic, #39;Engineering genetic cures: employing zinc finger nucleases (ZFNs) in stem cells. #39; The Stem Cells Regenerative Medicine Congress is where pharma, biotech, academia, government and investors come to uncover the technologies, strategies and business models that will help get stem cell and regenerative medicine treatments to market faster and more cost effectively. For more information, go to http://www.terrapinn.com/stemcellsusa. Or, check out our blog at blogs.terrapinn.com/total-biopharma for up to date information on the stem cells, RM and cord blood banking and therapeutics sectors.From:biopharmachannelViews:0 0ratingsTime:24:15More inScience Technology

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Teresa Leezer of Rhinocyte on neurodegenerative conditions – at Stem Cells USA

Posted: December 21, 2012 at 9:43 am


Teresa Leezer of Rhinocyte on neurodegenerative conditions - at Stem Cells USA RM Congress 2012
Teresa Leezer, COO of Rhinocyte, spoke at the Stem Cells USA Regenerative Medicine Congress 2012 on the topic, #39;Using autologous olfactory epithelial cells to treat neurodegenerative conditions. #39; The Stem Cells Regenerative Medicine Congress is where pharma, biotech, academia, government and investors come to uncover the technologies, strategies and business models that will help get stem cell and regenerative medicine treatments to market faster and more cost effectively. For more information, go to http://www.terrapinn.com/stemcellsusa. Or, check out our blog at blogs.terrapinn.com/total-biopharma for up to date information on the stem cells, RM and cord blood banking and therapeutics sectors.From:biopharmachannelViews:0 0ratingsTime:14:58More inScience Technology

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Teresa Leezer of Rhinocyte on neurodegenerative conditions - at Stem Cells USA

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Michael West of BioTime on hES cell-based therapies – at Stem Cells USA

Posted: December 21, 2012 at 9:43 am


Michael West of BioTime on hES cell-based therapies - at Stem Cells USA RM Congress 2012
Michael West, CEO of BioTime, spoke at the Stem Cells USA Regenerative Medicine Congress 2012 on the topic, #39;Second generation hES cell-based therapies: achieving purity and scalability in the midst of diversity. #39; The Stem Cells Regenerative Medicine Congress is where pharma, biotech, academia, government and investors come to uncover the technologies, strategies and business models that will help get stem cell and regenerative medicine treatments to market faster and more cost effectively. For more information, go to http://www.terrapinn.com/stemcellsusa. Or, check out our blog at blogs.terrapinn.com/total-biopharma for up to date information on the stem cells, RM and cord blood banking and therapeutics sectors.From:biopharmachannelViews:0 0ratingsTime:23:31More inScience Technology

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Michael West of BioTime on hES cell-based therapies - at Stem Cells USA

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Ed Field of Cytomedix on biotech collaboration in RM – at Stem Cells USA

Posted: December 21, 2012 at 9:43 am


Ed Field of Cytomedix on biotech collaboration in RM - at Stem Cells USA RM Congress 2012
Ed Field, Chief Operating Officer of Cytomedix, spoke at the Stem Cells USA Regenerative Medicine Congress 2012 on the topic, #39;Biotech collaboration in RM: Cytomedix #39;s acquisition of Aldagen. #39; The Stem Cells Regenerative Medicine Congress is where pharma, biotech, academia, government and investors come to uncover the technologies, strategies and business models that will help get stem cell and regenerative medicine treatments to market faster and more cost effectively. For more information, go to http://www.terrapinn.com/stemcellsusa. Or, check out our blog at blogs.terrapinn.com/total-biopharma for up to date information on the stem cells, RM and cord blood banking and therapeutics sectors.From:biopharmachannelViews:0 0ratingsTime:24:03More inScience Technology

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