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Acumen Pharmaceuticals Presents Patient Experience and Biomarker Data from Phase 1 INTERCEPT-AD Study at the Alzheimer’s Association International…

Posted: July 29, 2024 at 2:32 am

NEWTON, Mass., July 28, 2024 (GLOBE NEWSWIRE) -- Acumen Pharmaceuticals, Inc. (NASDAQ: ABOS), a clinical-stage biopharmaceutical company developing a novel therapeutic that targets toxic soluble amyloid beta oligomers (A?Os) for the treatment of Alzheimer’s disease (AD), today announced new findings from its Phase 1 INTERCEPT-AD study of sabirnetug (ACU193). The research highlights the experiences of patients in the clinical trial to inform development of future trials, biomarker data to support sabirnetug’s mechanism of action, and an ultra-sensitive method of measuring small amounts of sabirnetug in cerebrospinal fluid (CSF). The posters will be presented at the Alzheimer’s Association International Conference (AAIC®) 2024 taking place in Philadelphia and online from July 28-Aug. 1, 2024.

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Regeneration Biomedical to Present Data on First Two Subjects in a Phase I Clinical Trial of Stem Cell Therapy delivered directly into the brains of…

Posted: July 29, 2024 at 2:32 am

Wnt-activated, autologous, expanded, adipose-derived stem cells administered directly into lateral ventricles of the brain via Ommaya reservoir implanted under the scalp to bypass blood brain barrier

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Longeveron® Presents Study Results from CLEAR MIND Phase 2a Clinical Trial of Lomecel-B™ in Mild Alzheimer’s Disease at the Alzheimer’s…

Posted: July 29, 2024 at 2:32 am

– Featured Research Session oral presentation highlights findings that show Lomecel-B™ improved cognitive function, quality of life, and brain volume in the treatment of mild Alzheimer’s Disease –

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Roche closes acquisition of LumiraDx’s Point of Care technology to expand access to diagnostic testing in primary care

Posted: July 29, 2024 at 2:32 am

Basel, 29 July 2024 - Roche (SIX: RO, ROG; OTCQX: RHHBY) announced today the completion of the acquisition of LumiraDx’s Point of Care technology, following the receipt of all required antitrust and regulatory clearances. Roche will now embark on the full integration of the company’s innovative multi-assay point of care platform and the related R&D, operational and commercial sites into its global organisation.

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Roche closes acquisition of LumiraDx’s Point of Care technology to expand access to diagnostic testing in primary care

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DBV Technologies to Report Second Quarter 2024 Financial Results and Business Update on July 30, 2024

Posted: July 29, 2024 at 2:32 am

Châtillon, France, July 29, 2024

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DBV Technologies to Report Second Quarter 2024 Financial Results and Business Update on July 30, 2024

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CHMP adopts positive opinion recommending approval of new and expanded indications for SPEVIGO®

Posted: July 29, 2024 at 2:32 am

Boehringer Ingelheim today announced that the European Medicine Agency’s Committee for Medicinal Products for Human Use (CHMP) recommended approval of a new indication of SPEVIGO® (spesolimab) injection for the prevention of generalized pustular psoriasis (GPP) flares in adults and adolescents from 12 years of age; and extension of the approved indication for SPEVIGO® (spesolimab) infusion for the treatment of generalized pustular psoriasis (GPP) flares in adults and adolescents from 12 years of age as monotherapy. SPEVIGO® is a novel, humanized selective IgG1 antibody that binds to interleukin-36 receptor (IL-36R), a key part of a signaling pathway within the immune system shown to be involved in the cause of GPP.

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CHMP adopts positive opinion recommending approval of new and expanded indications for SPEVIGO®

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Chinese researchers make genetic breakthrough that could change the future of agriculture: ‘Powerful and transformative strategy’ – The Cool Down

Posted: July 21, 2024 at 2:38 am

Chinese scientists have reportedly engineered a way to use gene-editing technology to bypass natural plant behavior and force crops to inherit genes that will make them more resilient and easier to grow, according to Interesting Engineering.

"The genetic manipulation of wild plant populations has emerged as a potentially powerful and transformative strategy," the researchers said.

The technique involves using CRISPR gene-editing technology to bypass traditional Mendelian inheritance the process by which genes are passed down through generations to breed plants with "ideal" genes. The system is known as CRISPR-Assisted Inheritance, or CAIN.

"This gene drive-based approach thus seeks to balance crop protection and environmental considerations to minimise the loss of biodiversity while optimising productivity," the researchers wrote. "As we venture into this new frontier in genetic engineering, [CAIN] and other gene drive systems could reshape ecological management and agricultural practices."

All around the world, food supplies are being threatened by the consequences of human activities mainly, the usage of dirty energy sources like gas and oil that have caused our planet to overheat and weather patterns to become extreme and unpredictable. Rising global temperatures and increasingly widespread droughts have made many crops nonviable in areas where they have traditionally been grown.

It is vital that we stop this trend in its tracks by turning away from dirty energy and relying instead on clean, renewable sources of energy such as wind and solar.

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However, in the meantime, we must use technology to create more sustainable agricultural practices and food sources that can withstand more extreme weather conditions.

Some recent innovations in that field include the discovery of a genetic mechanism in pear trees that allows them to tolerate drought conditions, the discovery of a gene mutation in peach trees that lets them escape the effects of spring frost, and a genome-edited type of rice that is resistant to a devastating virus.

Any of these discoveries and breakthroughs could be applied to other crops, using CRISPR technology, to make them more resilient as well.

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Chinese researchers make genetic breakthrough that could change the future of agriculture: 'Powerful and transformative strategy' - The Cool Down

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Meet Thomas Vanhercke: innovating with passion – CSIRO

Posted: July 21, 2024 at 2:38 am

By James Chesters 16 July 2024 4 min read

Senior scientist Thomas Vanhercke didnt plan his career as much as he could have. When he was growing up, he followed his passion instead.

"In science you must be driven by passion, an insatiable thirst for knowledge, and lots of patience, Thomas says.

People always say to follow your heart. It might seem trivial, but its very important.

Following his passion has made Thomas who he is today. His passion for genetics started in high school. Then, he pursued a MSc and PhD in Bioengineering at Ghent University the birthplace of plant genetic engineering.Thomas was intrigued by how genetic research can be applied in agriculture.

Today, Thomas passion and skills make him an expert in metabolic engineering and synthetic biology. This involves genetically engineering microbes and plants to produce specific ingredients and molecules.Thomas leads teams tackling some of the biggest hurdles in food and agriculture.

Thomas Vanhercke currently leads our Synthetic Traits group, overseeing novel protein production research for our Future Protein mission.

Our agricultural and food systems face some serious challenges. From adapting to a changing climate to shifting towards more sustainable practices, Thomas says.

By 2050, the global population will reach 9.7 billion . This will cause the worlds annual demand for protein to almost double. With no more land available for grazing cattle, our current ways of producing protein cant meet future demand.

Malnutrition also remains one of the worlds greatest challenges. Even if food is readily available, people are often undernourished. This is from diets lacking in micronutrients like iron and zinc.

But Thomas is fascinated with how genetic engineering can unlock solutions to agricultural challenges. He sees opportunities where others see problems.

Our Future Protein research brings together expertise from many scientific disciplines and sectors. Were here to tackle the challenges ahead through a coordinated and sustained effort.

Thomas oversees novel protein production research for our Future Protein purpose-led innovation initiative. This means harnessing the potential in existing food streams to produce high-value ingredients.

Technologies like precision fermentation and molecular farming sound futuristic. But they help complement traditional food systems, such as livestock and broadacre crops.

Our scientists use precision fermentation and molecular farming to engineer microbes and plants. Theyre cooking up specific, customised molecules to serve as new ingredients. These will enhance the taste, texture, colour or mouthfeel of our foods.

This process has a long and safe history in supplementing and diversifying our foods. Technological advances have brought down the cost of precision fermentation. So now were using it to create new, high-value food products.

Were not just improving the consumer experience. Precision fermentation can create ingredients that address other concerns such as sustainability, nutrition, or animal welfare, Thomas says.

Red meat, dairy, and seafood are here to stay. These animal-based proteins will continue playing a vital role in human diets globally.

Proteins made through precision fermentation using ingredients like yeast complement animal-based sources. Theyll help us meet growing demand, without sacrificing on quality. This holistic approach offers more protein choices to suit individual dietary, nutritional and taste preferences.

Were not just improving the consumer experience. Precision fermentation can create ingredients that address other concerns such as sustainability, nutrition, or animal welfare, Thomas says.

Thomas says were starting to see lot of activity and investment in this space. This includes developing hybrid food products that combine animal-, plant- and fermentation-derived ingredients.

I think the next exciting frontier will be the boundaries between different food production systems. For example, making sure that no food byproducts go to waste, he says.

Thomas also heads up our Synthetic Traits research, applying engineering principles to plants. Their successes include developing the science for canola crops with high levels of healthy omega-3 oils.

Synthetic biology applies engineering principles to biology. In other words, creating solutions from natures building blocks.

For example, Thomas and his team are working on new crops that can convert their own nitrogen for growth. This will help farmers to use less nitrogen fertiliser which impacts the environment while still growing enough food.

Thomas is clear that great science needs diversity. He believes that innovation relies on people with different knowledge and skills coming together. This diversity could range from technical expertise to research infrastructure. It incorporates business development and intellectual property knowledge, as well as delving into market trends.

No one can do everything by themselves, we each stand on the shoulders of many others, Thomas says.

Diversity of knowledge, experience, and thought are critical, he says.

Thomas has big ideas about how to inspire the next generation of scientists. He believes role models, mentoring, and a strong science curriculum are all important.

I encountered several inspiring people along the way who have gently helped me in stepping outside my comfort zones and have pushed me in the right direction, Thomas says.

Hopefully I am continuing their example by inspiring others around me.

Since taking on more responsibilities as a leader, Thomas doesnt get to spend as much time in the lab. Sometimes wearing a white coat can feel odd. But he takes satisfaction in mentoring others and seeing the excitement when a great result comes in.

Thomas doesnt hesitate when asked what he enjoys most about his work.

I love collaborating with colleagues from diverse science backgrounds when developing new ideas. And thinking about the next frontier in research innovation and impact. That is really the coolest part of my job, he says.

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Meet Thomas Vanhercke: innovating with passion - CSIRO

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Genetically Modified (GMO) Food Market size is set to grow by USD 46.8 billion from 2024-2028, High demand for crop production boost the market,…

Posted: July 21, 2024 at 2:38 am

NEW YORK, July 17, 2024 /PRNewswire/ -- The globalgenetically modified (GMO) food marketsize is estimated to grow by USD 46.8 billion from 2024-2028, according to Technavio. The market is estimated to grow at a CAGR of 7.07% during the forecast period. High demand for crop productionis driving market growth,with a trend towardsinnovations in gene-editing technologies. However,increase in demand for organic food products poses a challenge. Key market players include BASF SE, Bayer AG, Cibus, Corteva Inc., FMC Corp., Groupe Limagrain, JK Agri Genetics Ltd., KWS SAAT SE and Co. KGaA, Rasi Seeds P Ltd., Sakata Seed Corp., Stine Seed Co., Syngenta Crop Protection AG, Tata Sons Pvt. Ltd., Terranova Seeds Australia, and UPL Ltd..

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Genetically Modified (GMO) Food Market Scope

Report Coverage

Details

Base year

2023

Historic period

2017 - 2021

Forecast period

2024-2028

Growth momentum & CAGR

Accelerate at a CAGR of 7.07%

Market growth 2024-2028

USD 46.8 billion

Market structure

Fragmented

YoY growth 2022-2023 (%)

6.43

Regional analysis

North America, APAC, Europe, South America, and Middle East and Africa

Performing market contribution

APAC at 35%

Key countries

US, China, Japan, Canada, and France

Key companies profiled

BASF SE, Bayer AG, Cibus, Corteva Inc., FMC Corp., Groupe Limagrain, JK Agri Genetics Ltd., KWS SAAT SE and Co. KGaA, Rasi Seeds P Ltd., Sakata Seed Corp., Stine Seed Co., Syngenta Crop Protection AG, Tata Sons Pvt. Ltd., Terranova Seeds Australia, and UPL Ltd.

Market Driver

The global genetically modified food market is experiencing significant growth due to the premium pricing of non-genetically modified food products. Consumers, while health-conscious, often base their purchasing decisions on affordability. In the US, over half of the population expresses concerns about genetically modified food, but the health effects remain unclear. As non-genetically modified food prices continue to rise, consumers may switch to genetically modified alternatives during the forecast period. Reasonable pricing and uncertainty surrounding the health effects of genetically modified food are key factors driving market growth.

Genetically Modified (GMO) food market is witnessing significant trends in food security through the use of gene technology and genome editing. Key crops like herbicide resistant soybeans, insecticide resistant soybeans, corn, canola, sweet potato, rice, and others are being modified to increase yield and reduce reliance on harmful pesticides. New innovations include the addition of essential nutrients like iron and vitamins in foods, such as bananas and rice. Recombinant DNA technology and transgenic crops are revolutionizing the industry, leading to the production of vaccines for infectious diseases like Hepatitis B, and even new plastics. However, there are risks and controversies surrounding GMOs, including health concerns, consumer choice, ethics, and environmental impact. Mechanisms for labeling and public education are crucial to address these issues and ensure food safety. New technologies, such as gene manipulation, continue to emerge, raising questions about potential allergens and antibiotic resistance. The market for genetically modified foods, also known as transgenic and genetically engineered foods, is expected to grow, but addressing public concerns and ensuring safety remains a top priority. The potential for poverty reduction and advancements in fish farming and human health are also significant opportunities for the industry.

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MarketChallenges

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Segment Overview

This genetically modified (gmo) food market report extensively covers market segmentation by

1.1 Vegetables- Genetically modified vegetables offer advantages such as faster growth and higher yields, making them valuable in meeting the increasing food demand. These modifications also provide resistance to pests and diseases, reducing the need for chemical pesticides and minimizing crop losses. Additionally, genetically modified vegetables can withstand extreme weather conditions, enhancing their resilience to climate change. The global vegetable market is expected to grow due to factors like the expanding food industry, rising consumer expenditure, and increasing health consciousness. The vegetable segment is particularly driven by the growing vegan population and the demand for exotic vegetables. Consumers in both developed and developing nations have higher disposable incomes, leading to increased demand. Genetically modified vegetables are accessible through offline and online retail channels, with the latter gaining popularity due to the convenience and wide variety of offerings, including exotic vegetables. The growing disposable income, especially in emerging economies, and the demand for exotic vegetables will fuel the growth of the vegetable segment in the global genetically modified food market.

For more information on market segmentation with geographical analysis including forecast (2024-2028) and historic data (2017-2021) - Download a Sample Report

Learn and explore more about Technavio's in-depth research reports

The global plant-based protein products market is witnessing robust growth due to rising health consciousness and increasing veganism trends. Key players are innovating to meet the demand for sustainable and nutritious alternatives. Similarly, the global non-GMO food market is expanding as consumers seek healthier and more natural food options. The demand for transparency and food safety is driving this market, with significant contributions from major food brands and organic producers. Both markets are poised for substantial growth, driven by consumer preferences and evolving dietary trends.

Research Analysis

The genetically modified (GMO) food market refers to the production and consumption of nutrition-rich foods derived from organisms with altered genetic structures. This involves the use of genetic modification techniques, such as gene technology and recombinant DNA technology, to introduce better characteristics into plants and animals. Edible organisms, including soybeans, cotton, corn, canola, and sweet potato, are commonly modified to enhance traits like herbicide tolerance, insect resistance, and stacked traits. These modifications aim to improve conditions for farmers, such as increased shelf life and resistance to pests, while maintaining or enhancing the nutritional value of the food. Microorganisms are also used in the production of GMO foods through various genetic engineering techniques. The result is a diverse range of transgenic crops and herbicide resistant soybeans, insecticide resistant soybeans, and other GMO foods that offer improved characteristics for farmers and consumers alike.

Market Research Overview

The Genetically Modified (GM) food market encompasses a wide range of nutrition-rich foods derived from genetically modified organisms (GMOs), including plants and animals. These edible organisms exhibit better characteristics under specific conditions, such as longer shelf life, sweet flavor, and better texture, making them highly sought-after in today's global market. The demand for GM foods continues to grow due to their health benefits, which include combating diseases like cancer and gastrointestinal discomfort, as well as addressing allergies caused by pesticides and toxic substances. Innovative products in the GM food market include beverages, food processing techniques, and taste preferences. Genetic engineering techniques, such as gene guns, electroporation, microinjection, Agrobacterium, transgenic, cis-genic, and sub-genic methods, are used to introduce desirable traits like herbicide tolerance, insect resistance, and stacked traits into agricultural crops, animal feed, and even food waste reduction. Trait types include nitrogen fixing crops, haploid induction techniques, and gene stacking, among others. Companies like Origin Agritech, Monsanto, COODETEC, Nidera, Sensako, and others are at the forefront of this industry, driving food security through genome editing, gene technology, and the development of living organisms and microorganisms using recombinant DNA technology. GM foods extend beyond crops to include transgenic soybeans, corn, canola, sweet potato, rice, and even human vaccines for infectious diseases like hepatitis B. The future of the GM food market holds exciting possibilities, with the advent of CRISPR technologies and the development of iron-fortified bananas and vitamin-enriched rice.

Table of Contents:

1 Executive Summary 2 Market Landscape 3 Market Sizing 4 Historic Market Size 5 Five Forces Analysis 6 Market Segmentation

7Customer Landscape 8 Geographic Landscape 9 Drivers, Challenges, and Trends 10 Company Landscape 11 Company Analysis 12 Appendix

About Technavio

Technavio is a leading global technology research and advisory company. Their research and analysis focuses on emerging market trends and provides actionable insights to help businesses identify market opportunities and develop effective strategies to optimize their market positions.

With over 500 specialized analysts, Technavio's report library consists of more than 17,000 reports and counting, covering 800 technologies, spanning across 50 countries. Their client base consists of enterprises of all sizes, including more than 100 Fortune 500 companies. This growing client base relies on Technavio's comprehensive coverage, extensive research, and actionable market insights to identify opportunities in existing and potential markets and assess their competitive positions within changing market scenarios.

Contacts

Technavio Research Jesse Maida Media & Marketing Executive US: +1 844 364 1100 UK: +44 203 893 3200 Email:[emailprotected] Website:www.technavio.com/

SOURCE Technavio

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COVID tied to faster progression from preclinical to clinical type 1 diabetes in kids – University of Minnesota Twin Cities

Posted: July 21, 2024 at 2:38 am

Karen Jackson / Flickr cc

A new prevalence study of the common foodborne bacterium Campylobacter in North Carolina chickens shows it is almost twice as common in backyard flocks than on commercial farms, and isolates are often resistant to antibiotics.

The authors say the findings are significant because chicken is the top consumed meat worldwide, and backyard poultry production is increasing in the United States. The results were published in JAC - Antimicrobial Resistance.

North Carolina State investigators obtained samples from 10 backyard and 10 commercial broiler farms in North Carolina to follow flocks throughout production. They collected fecal and environmental samples at days 10, 31, and 52 days post-hatch in backyard flocks and on days 10, 24, and 38 on commercial farms. Environmental samples were collected from the soil, litter/compost, and feeders and waterers.

Of samples collected from backyard flocks, 21.9% tested positive for Campylobacter, compared with 12.2% of the farm samples. Most of the isolates were identified asC jejuni(70.8%), with the restC coli(29.2%). The breakdown of positive sample locations in backyard farms was 70.2% from fecal samples, 6.4% from soil, 3.5% from litter/compost, and 19.9% from swabs of feeders and waterers. For commercial farms, the rates were 84.2%, 0%, 12.6%, and 3.2%, respectively.

We found a higher proportion of resistant isolates in commercial farms, with unprecedented higher levels inC. jejuniversusC. coli.

Antimicrobial susceptibility testing revealed phenotypic resistance to ciprofloxacin (40.2%), an important treatment drug forCampylobacter, and tetracycline (46.6%). The researchers found a higher proportion of resistance inC jejuniisolates and on the commercial farms.

The authors concluded, "Despite higher prevalence in backyard farms, we found a higher proportion of resistant isolates in commercial farms, with unprecedented higher levels inC. jejuniversusC. coli."

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COVID tied to faster progression from preclinical to clinical type 1 diabetes in kids - University of Minnesota Twin Cities

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