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Update: Bioheart Partnership With Stemlogix Leads to First in U.S. Combination Regenerative Medicine Treatment on …

Posted: December 5, 2012 at 2:48 pm

SUNRISE, FL--(Marketwire - Dec 4, 2012) - Bioheart Inc. ( OTCQB : BHRT ) previouslyannounced that its cGMP facility would be utilized by Stemlogix to help promote regenerative medicine for the veterinary market.Stemlogix has just announced the first ever combination regenerative medicine treatment on a six-year-old Quarter Reined Cow horse that suffered a significant injury to its distal straight sesamoidean ligament.

"The facilities at Bioheart Inc. are top notch and we are excited to move these new therapies for animals forward using state-of-the-art cGMP laboratories.We are fortunate to have the support and expertise of the Bioheart team," said Jason Griffeth, Chief Operating Officer of Stemlogix, LLC.

To provide him with this groundbreaking treatment, two small fat samples were taken from the base of his tail via a minimally invasive lipoaspirate procedure. Fat tissue is the richest source of stem cells for both human patients and animal patients. One of the tissue samples was processed on-site to provide a same-day, point-of-care stem cell treatment while the other tissue sample was sent to the cGMP laboratory where the mesenchymal stem cells were isolated and expanded for three weeks. A portion of his stem cells were also cryopreserved for future use.

Bioheart's president and CEO, Mike Tomas said, "Bioheart is focused on commercializing cell therapies for cardiac patients and has many years' experience with a variety of different cell types.This partnership allows us to utilize our existing laboratories and expertise to bring these products to the veterinary market."

About Bioheart, Inc.

Bioheart is committed to maintaining its leading position within the cardiovascular sector of the cell technology industry delivering cell therapies and biologics that help address congestive heart failure, lower limb ischemia, chronic heart ischemia, acute myocardial infarctions and other issues.Bioheart's goals are to cause damaged tissue to be regenerated, when possible, and to improve a patient's quality of life and reduce health care costs and hospitalizations.

Specific to biotechnology, Bioheart is focused on the discovery, development and, subject to regulatory approval, commercialization of autologous cell therapies for the treatment of chronic and acute heart damage and peripheral vascular disease. Its leading product, MyoCell, is a clinical muscle-derived cell therapy designed to populate regions of scar tissue within a patient's heart with new living cells for the purpose of improving cardiac function in chronic heart failure patients. For more information on Bioheart, visit http://www.bioheartinc.com, or visit us on Facebook: Bioheart and Twitter @BioheartInc.

About Stemlogix, LLC

Stemlogix high quality stem cell therapy and other regenerative medicine therapies are impacting the lives of cats, dogs and horses around the U.S. and in other countries. The company has developed a scientifically validated method for harvesting stem cells from both fat tissue and bone marrow for therapeutic use. The Stemlogix stem cell isolation processes provide for consistent cellular products that are compliant with current regulatory guidelines. Stemlogix has a highly experienced management team with over 20 years combined experience in developing multiple stem cell therapeutics for both human and animal use. In all of its products and services, Stemlogix aims to provide the best cutting-edge regenerative medical solutions, and seeks to provide companion animals and horses with renewed health and vitality. The company has partnered with Butler Schein Animal Health, the leading companion animal health distribution company in the U.S., who are demonstrating the ease and effectiveness of the Stemlogix regenerative medicine treatments to veterinarians nationwide. To learn more about Stemlogix, LLC and its wide range of innovative regenerative medicine products please visit http://www.stemlogix.com, send an email to info@stemlogix.com or contact your local Butler Schein Animal Health representative.

Forward-Looking Statements: Except for historical matters contained herein, statements made in this press release are forward-looking statements. Without limiting the generality of the foregoing, words such as "may," "will," "to," "plan," "expect," "believe," "anticipate," "intend," "could," "would," "estimate," or "continue" or the negative other variations thereof or comparable terminology are intended to identify forward-looking statements.

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Research and Markets: Stem Cell & Regenerative Medicine

Posted: December 5, 2012 at 2:48 pm

DUBLIN--(BUSINESS WIRE)--

Research and Markets (http://www.researchandmarkets.com/research/6kl7tg/stem_cell_and) has announced the addition of the "Stem Cell & Regenerative Medicine" book to their offering.

The potential use of stem cells in transplantation for the purpose of tissue regeneration is an exciting area of research currently undergoing rapid development. Implantation of human embryonic or autologous, ex vivo-expanded adult stem cells, particularly in older individuals, could circumvent the limited availability of organs/tissues as well as prevent complications related to immune rejection and disease transmission. Musculoskeletal tissue degeneration is closely associated with aging. Strategies employing autologous adult MSCs from older individuals for transplantation in order to regenerate their own ailing organ or tissues require that we vigorously define MSCs capacity to maintain growth potential and differentiation potential into the desirable cell lineages. We are currently restricted by the limited knowledge about physical parameters, such as biomechanical forces, that influence MSC growth and differentiation capacities. This is particularly important for MSCs isolated from older individuals, for whom little information is available.

This special volume aims to serve as an impetus in generating more interest among stem cell researchers and biotechnologists to improve and develop the cell-based therapies of damaged tissue using stem cells.

Topics Covered:

Foreword

Preface

Contributors

CHAPTERS

1 Justice and Vulnerability in Human Embryonic Stem Cell Research

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Research and Markets: Stem Cell & Regenerative Medicine

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Precision StemCell’s Neural Reprogrammed Stem Cell Therapy Yields Better-Than-Expected Results for ALS Patients

Posted: December 5, 2012 at 2:44 pm

GULF SHORES, Ala., Dec. 4, 2012 /PRNewswire/ --More than 75 percent of amyotrophic lateral sclerosis (ALS) patients who received neural reprogrammed stem cell therapy have shown a positive response to the procedure. The groundbreaking technique was introduced to the United States this year by Precision StemCell (http://www.precisionstemcell.com), an outpatient imaging and image-guided treatment facility located in Gulf Shores, Ala.

The procedure is performed by Dr. Jason R. Williams, a board-certified radiologist with extensive training in image-guided procedures. Under his care, 14 out of 18 patients diagnosed with ALS, also known as Lou Gehrig's disease, have shown signs of recovery.

"The improvements are mild, with patients reporting improved movement, breathing and speech, but we still have a long way to go," Dr. Williams stated. "Only time will tell how this therapy will affect the patients' long-term prognosis."

In Precision StemCell's neural reprogrammed stem cell therapy, fat-derived stem cells are injected into the spine of the patient. Dr. Williams uses a drug called selegeline, which has been shown to be a pre-inducer of adipose-derived stem cells into neural-like cells. Dr. Williams contends that the therapy is probably one of the largest advances seen in ALS therapy. "Before we started this therapy, I would have been happy just to see the progression of the disease halted, but to see some actual improvement, that was just shocking," he said

The first patient treated with the technique was Frank Orgel who continues to see improvement since his first treatment seven months ago. Eight years ago, Orgel's quality of life had declined to the point that he could not move his left arm or leg, walk or even stand on his own. The therapy has allowed Orgel to stand without assistance, and he continues to work with a physical therapist to regain the ability to walk. Another patient, Dexter Johnson, previously walked with a cane. After the treatment, Johnson has been able to walk without his cane for the majority of the time and he has been able to walk at a much faster pace.

The Precision StemCell center focuses on advanced imaging techniques, which include a 3T Open MRI, a low-dose 64-Slice CT Scanner, ultrasound and fluoroscopy, also known as real-time x-ray. The center is headed by Dr. Williams, who specializes in image-guided procedures, had already been performing magnetic resonance imaging (MRI), computed tomography (CT), ultrasound and fluoroscopy-guided stem cell injections for joint and orthopedic conditions.

In addition to their current work on advanced stem cell harvesting and processing with image-guided stem cell injections, Precision StemCell staff are planning to conduct further research so as to develop even more advanced techniques such as adding gene therapy to the current neural reprogramming platform. "Our therapy techniques not only hold promise for ALS patients, but also for people with other neural-related conditions such as Parkinson's and spinal cord injuries," said Dr. Williams. "There are several candidate genes that we plan to add to the adipose-derived stem cells and study in the mouse model. Though we are happy with our initial progress, our goal is to develop an effective cure."

About Precision StemCell

Located in Gulf Shores, Alabama, Precision StemCell conducts stem cell procedures using advanced imaging techniques, which include an Open 3T MRI, a low-dose 64-Slice CT scanner, ultrasound, and real time x-ray (fluoroscopy). Headed by Jason Williams, MD, a board-certified radiologist with extensive training in image-guided procedures, the facility performs advanced stem cell harvesting and processing with image-guided stem cell injections.

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Precision StemCell's Neural Reprogrammed Stem Cell Therapy Yields Better-Than-Expected Results for ALS Patients

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Precision StemCell's Neural Reprogrammed Stem Cell Therapy Yields Better-Than-Expected Results for ALS Patients

Posted: December 5, 2012 at 6:40 am

GULF SHORES, Ala., Dec. 4, 2012 /PRNewswire/ --More than 75 percent of amyotrophic lateral sclerosis (ALS) patients who received neural reprogrammed stem cell therapy have shown a positive response to the procedure. The groundbreaking technique was introduced to the United States this year by Precision StemCell (http://www.precisionstemcell.com), an outpatient imaging and image-guided treatment facility located in Gulf Shores, Ala.

The procedure is performed by Dr. Jason R. Williams, a board-certified radiologist with extensive training in image-guided procedures. Under his care, 14 out of 18 patients diagnosed with ALS, also known as Lou Gehrig's disease, have shown signs of recovery.

"The improvements are mild, with patients reporting improved movement, breathing and speech, but we still have a long way to go," Dr. Williams stated. "Only time will tell how this therapy will affect the patients' long-term prognosis."

In Precision StemCell's neural reprogrammed stem cell therapy, fat-derived stem cells are injected into the spine of the patient. Dr. Williams uses a drug called selegeline, which has been shown to be a pre-inducer of adipose-derived stem cells into neural-like cells. Dr. Williams contends that the therapy is probably one of the largest advances seen in ALS therapy. "Before we started this therapy, I would have been happy just to see the progression of the disease halted, but to see some actual improvement, that was just shocking," he said

The first patient treated with the technique was Frank Orgel who continues to see improvement since his first treatment seven months ago. Eight years ago, Orgel's quality of life had declined to the point that he could not move his left arm or leg, walk or even stand on his own. The therapy has allowed Orgel to stand without assistance, and he continues to work with a physical therapist to regain the ability to walk. Another patient, Dexter Johnson, previously walked with a cane. After the treatment, Johnson has been able to walk without his cane for the majority of the time and he has been able to walk at a much faster pace.

The Precision StemCell center focuses on advanced imaging techniques, which include a 3T Open MRI, a low-dose 64-Slice CT Scanner, ultrasound and fluoroscopy, also known as real-time x-ray. The center is headed by Dr. Williams, who specializes in image-guided procedures, had already been performing magnetic resonance imaging (MRI), computed tomography (CT), ultrasound and fluoroscopy-guided stem cell injections for joint and orthopedic conditions.

In addition to their current work on advanced stem cell harvesting and processing with image-guided stem cell injections, Precision StemCell staff are planning to conduct further research so as to develop even more advanced techniques such as adding gene therapy to the current neural reprogramming platform. "Our therapy techniques not only hold promise for ALS patients, but also for people with other neural-related conditions such as Parkinson's and spinal cord injuries," said Dr. Williams. "There are several candidate genes that we plan to add to the adipose-derived stem cells and study in the mouse model. Though we are happy with our initial progress, our goal is to develop an effective cure."

About Precision StemCell

Located in Gulf Shores, Alabama, Precision StemCell conducts stem cell procedures using advanced imaging techniques, which include an Open 3T MRI, a low-dose 64-Slice CT scanner, ultrasound, and real time x-ray (fluoroscopy). Headed by Jason Williams, MD, a board-certified radiologist with extensive training in image-guided procedures, the facility performs advanced stem cell harvesting and processing with image-guided stem cell injections.

Contact:

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Precision StemCell's Neural Reprogrammed Stem Cell Therapy Yields Better-Than-Expected Results for ALS Patients

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How Stem Cell in Bone Marrow Works.wmv – Video

Posted: December 4, 2012 at 12:43 pm


How Stem Cell in Bone Marrow Works.wmv
Question: What will happen when our bone marrow cell dead and finish? Answer: Message from effected tissue will travel through the blood to the bone marrow. Then, the stem cell will divide. When 1 stem cell released into the blood circulation, the other 1 will remain in the bone marrow to maintain the constant population of the stem cells in the bone marrow. When we aged, our stem cells become compromised... that #39;s why adults have a slower recovery compared to kids. Here is where the StemEnhance AFA comes in, to support the release of our stem cells naturally... facebook : http://www.facebook.com/stemenhanceafa website : bit.lyFrom:Siti Masrina SulongViews:4 1ratingsTime:01:09More inScience Technology

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How Stem Cell in Bone Marrow Works.wmv - Video

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Advent stem cells and the question of Life – Video

Posted: December 4, 2012 at 12:43 pm


Advent stem cells and the question of Life
From:YusefAlTahirViews:16 3ratingsTime:09:36More inPeople Blogs

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Advent stem cells and the question of Life - Video

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Embryonic Stem Cell Controversy – Video

Posted: December 4, 2012 at 12:43 pm


Embryonic Stem Cell Controversy
Class Project on Stem CellsFrom:kimboslicingapplesViews:0 0ratingsTime:02:12More inEducation

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Embryonic Stem Cell Controversy - Video

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Beyond the Visible: Adult Stem Cells and Cancer – Video

Posted: December 4, 2012 at 12:43 pm


Beyond the Visible: Adult Stem Cells and Cancer
Docent Petri Salvn has spent two decades researching the mechanisms of angiogenesis - the growth of new blood vessels - to identify ways to accelerate or block it. He is particularly intrigued by the source of highly specialised endothelial cells in blood-vessel walls and by the possibility to enhance or prevent the generation of such cells. Researchers track down stem cells in blood vessel walls: http://www.helsinki.fi Music: Travis Morgan, Time Decay (ccmixter.org) Filmed by Claudia GorrFrom:universityofhelsinkiViews:16 0ratingsTime:02:19More inScience Technology

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Beyond the Visible: Adult Stem Cells and Cancer - Video

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A Medical Revolution PSA- Stem Cells – Video

Posted: December 4, 2012 at 12:43 pm


A Medical Revolution PSA- Stem Cells
ENGL 1311 Final ProjectFrom:dgnajera2Views:0 0ratingsTime:00:53More inEducation

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A Medical Revolution PSA- Stem Cells - Video

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TEDxSalford – Sir Ian Wilmut – From Dolly to Curing Human Disease – Video

Posted: December 4, 2012 at 12:43 pm


TEDxSalford - Sir Ian Wilmut - From Dolly to Curing Human Disease
Sir Ian Wilmut is a world-renowned embryologist and specialist in regenerative medicine. He is best known as the man who led the team that in 1996 first cloned a mammal, a Finn Dorset lamb named "Dolly". Dolly was the first ever clone derived from an adult cell. The research resulting in Dolly #39;s birth stemmed from efforts to genetically engineer sheep and cows in order that their milk would contain human proteins with medicinal properties, such as human antibodies. More recently he was the founding Director of the Centre for Regenerative Medicine in the University of Edinburgh. The Mission of this rapidly expanding Centre is to develop new treatments for human disease through innovative research with stem cells. The new Centre covers the full spectrum of research -- from basic mechanisms of stem cell biology, to clinical trials with stem cells and their derivatives. The aim of his own research is to be able to produce human cells for use in research and in future for treatment of diseases, such as motor Neuron Disease. In his talk he will describe the way in which the cloning research has provided revolutionary new opportunities in regenerative medicine. Credits: Camerawork: Nathan Rae Team - nathanrae.co.uk Post production: Elliott Wragg - twitter.com Audio restoration : Jorge Polvorinos - jorgepolvorinos.wordpress.com Heat of IT and Design Vlad Victor Jiman - twitter.comFrom:TEDxTalksViews:5 1ratingsTime:19:27More inNonprofits Activism

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TEDxSalford - Sir Ian Wilmut - From Dolly to Curing Human Disease - Video

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