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Kanpur hospital is Indias first to perform fat-derived stem cell transplant for diabetic patients – India Today

Posted: August 30, 2022 at 2:14 am

A hospital in Kanpur became the first in India to perform fat-derived stem cell transplant for diabetic patients.

A 50-year-old man became the first recipient of derived stem cell transplant in the country. (Photo: India Today)

The LLR government hospital in Kanpur has become the first hospital in the country to perform the first fat-derived stem cell transplant. This has come as good news for all the patients with type 2 diabetes who have to take insulin frequently.

In this method, stem cells are extracted from waist and abdominal fat and injected into the patient's muscles and blood cells. This will help the patient's pancreas (beta cells) to release normal amount of insulin.

The 50-year-old male recipient of this first adipose-derived stem cell transplant in the country has been suffering from type 2 diabetes for the past five years.

According to doctors, the cost of this transplant so far is Rs 2.5 lakh and in the near future the cost is expected to come down and the treatment will be cheaper for many people suffering from type 2 diabetes.

The stem cell approach will continue to offer a new ray of hope to patients and their families.

This operation is called fat-derived step transfer which takes place after removing the fatty tissue from the patient himself and then processing it with patented technology from Australia. So, the cost of the machine is Rs 1 crore and operation cost is Rs 2,52,000, said Dr Sanjay Kala, Principal of GSVM Medical College, Kanpur.

So far, we have only read about the response to stem cell transplant in diabetic patients in books. But this has been done for the first time in the country. Insulin and other supplements prove to be expensive in the long term. With this, we can give a pill or dose of stem cell therapy and a patient with diabetes can be cured, added Dr Sanjay Kala.

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Scientists Just Genetically Edited a Million Years of Evolution Into Mouse DNA – ScienceAlert

Posted: August 30, 2022 at 2:14 am

Changing the number of chromosomes an animal has can take millions of generations to happen in nature through the course of evolution and now, scientists have been able to make these same changes in lab mice in a relative blink of an eye.

The new technique using stem cells and gene editing is a major accomplishment, and one that the team is hoping will reveal more about how the rearrangement of chromosomes can influence the way that animals evolve over time.

It's in chromosomes those strings of protein and DNA inside cells that we find our genes, inherited from our parents and blended together to make us who we are.

For mammals like mice and us humans, chromosomes typically come paired. There are exceptions, such as in sex cells.

Unfertilized embryonic stem cells are usually the best starting place for tinkering with DNA. Lacking that additional set of chromosomes provided by a sperm cell, though, deprives the cells of an important step in negotiating which genes in which chromosomes will be marked active to do the job of building a body.

This process called imprinting was a stumbling block for engineers keen to restructure large chunks of the genome.

"Genomic imprinting is frequently lost, meaning the information about which genes should be active disappears in haploid embryonic stem cells, limiting their pluripotency and genetic engineering," says biologist Li-Bin Wang from the Chinese Academy of Sciences.

"We recently discovered that by deleting three imprinted regions, we could establish a stable sperm-like imprinting pattern in the cells."

Without those three naturally imprinted regions, lasting chromosome fusion was possible. In their experiments, the researchers fused two medium-sized chromosomes (4 and 5) and the two largest chromosomes (1 and 2) in two different orientations, resulting in three different arrangements.

The fusion of chromosomes 4 and 5 was the most successful in terms of the genetic code being passed on to the mice offspring, although breeding was slower than normal.

One of the 1 and 2 fusions produced no mice offspring, while the other produced mice offspring that were slower, larger, and more anxious than those from the fusion of chromosomes 4 and 5.

According to the researchers, the drops in fertility are down to how the chromosomes separate after alignment, which doesn't happen in the normal way. It shows that chromosomal rearrangement is crucial to reproductive isolation a key part of species being able to evolve and stay separate.

"The laboratory house mouse has maintained a standard 40-chromosome karyotype or the full picture of an organism's chromosomes after more than 100 years of artificial breeding," says biologist Zhi-Kun Li, also from the Chinese Academy of Sciences.

"Over longer time scales, however, karyotype changes caused by chromosome rearrangements are common. Rodents have 3.2 to 3.5 rearrangements per million years, whereas primates have 1.6."

To put this into context, rare leaps in chromosomal rearrangement have helped direct the evolutionary paths of our own ancestors. Chromosomes that remain separate in gorillas, for instance, are fused into one in our human genome.

Those types of changes can occur once every few hundred millennia. While the genetic edits made here in the lab were on a relatively small scale, the signs are that they could have some dramatic effects on the animals involved.

It's still early days this is a scientific first after all but further down the line, there might be the opportunity to correct misaligned or malformed chromosomes in human bloodlines. We know that in individuals, chromosome fusions and relocations can lead to health problems including childhood leukemia.

"We experimentally demonstrated that the chromosomal rearrangement event is the driving force behind species evolution and important for reproductive isolation, providing a potential route for large-scale engineering of DNA in mammals," says Li.

The research has been published in Science.

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What I Learned When I Stopped Testosterone Replacement Therapy |… – Cushing’s Disease News

Posted: August 30, 2022 at 2:12 am

In 2018, I decided to stop using testosterone replacement therapy due to the side effects I was experiencing, most notably, increasingly aggressive behavior.

One concern I had at the time, though, was that ending the treatment would cause an increase in Cushings-related symptoms, because other hormones might be affected. This treatment had addressed my low testosterone levels caused by a pituitary tumor.

I do not recommend abruptly stopping treatment like I did without consulting a professional first. Although I am now seeing the benefits of my decision, it was not an easy road, and at one point, I began to question if my choice was the right one.

The first thing I noticed when I stopped taking my injections was that my mood deteriorated. Feelings of sadness led to an occasional lack of motivation. This sadness was partly due to my reluctance to stop the treatment. While I believed the medication was working, I became aware of how the side effects were affecting both me and those around me. Also, my body had grown accustomed to it over the past year, which led to more emotional imbalance.

The lows in my mood started to improve with effort, such as doing more research on ways to naturally balance testosterone levels, tinkering with areas of my life that were affected by testosterone, and being more active. Eventually, these strategies led to drastic change.

The second effect of stopping treatment was fatigue. The best way to describe it is like working outside all day in the heat. To combat it, what worked well for me was a combination of a plant-based caffeinated green drink, vitamin C, and vitamin B12. This drink has been part of my morning routine for the past four years, since ending testosterone replacement therapy.

I dont like coffee, so it was a good alternative. I also wanted to stay away from most store-bought caffeinated drinks due to their high sugar content.

Other issues I had to deal with again were pain and stiffness, mainly in my feet and lower back. If I was sitting or lying down, my feet would ache when I got up or tried to move. When standing, my lower back would get stiff. It didnt matter how long I was standing, it just appeared to happen randomly.Of the various side effects, the pain and stiffness took the longest to overcome.

To relieve the pain, my wife bought me some braces. I used them for a while but didnt experience much of a change. Then, one day, I started noticing that there was no more pain. This continued to improve each day. I suspect that the amount of weight I had been carrying due to Cushings disease was creating stress on the lower parts of my body, such as my knees. That might have compressed my spine, ankles, and feet. Once I began stretching and being more active including walking 2 miles a day these areas of my body grew stronger, which helped to alleviate the pain.

Given all of these experiences, I eventually learned that I had to give myself time. Quitting testosterone therapy wasnt a process with quick results. It helps to stay positive and motivated, and to take things one day at a time. The peaks and valleys of our journeys shouldnt discourage us from the goal of getting back to optimum health.

The decision to stop any treatment is not one to take lightly. Its always important to talk to your healthcare team before making any changes to a treatment regimen. Doctors can also help you develop a plan of action to replace a particular treatment, if needed.

Today, my energy levels are up again, Ive seen no signs of aggression in my behavior, and my overall sense of well-being has improved. For me, stopping testosterone replacement therapy was worth the trouble because it forced me to look at my mind and body as a whole. The trade-off has been beneficial, and it allowed me to live a healthier lifestyle.

Note:Cushings Disease Newsis strictly a news and information website about the disease. It does not provide medical advice,diagnosis, or treatment. This content is not intended to be a substitute for professional medical advice,diagnosis, or treatment. Always seek the advice of your physician or other qualified health provider with any questions you may have regarding a medical condition. Never disregard professional medical advice or delay in seeking it because of something you have read on this website. The opinions expressed in this column are not those ofCushings Disease Newsor its parent company, BioNews, and are intended to spark discussion about issues pertaining to Cushings.

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From White Plains Hospital: Feeling the Effects of Man-o-pause? – theLoop

Posted: August 30, 2022 at 2:12 am

Low testosterone levels known in some corners as man-o-pause are one of the byproducts of aging; according to the American College of Physicians (ACP), an age-associated decline in total testosterone levels begins in men in their mid-30s and gradually increases by an annual average rate of 1.6%. The ACP reports that the incidence of low testosterone in the U.S. stands at about 20% in men older than 60, 30% in those older than 70, and 50% in those older than 80.

I see a fair amount of patients in their mid-50s and older who tell me about how they feel more tired, that their erections arent what they used to be, and how they have less interest in having sex with their partner. With some of those patients, tests show that their testosterone levels are totally normal, so I find myself telling them, Welcome to middle age.

But that is not always the case. On average, a testosterone level of 3001,000 nanograms per deciliter (ng/dL) of blood is normal. Reduced testicular function is typically diagnosed when the total testosterone is less than 300 ng/dL.

Effects of declining testosterone levels can include a lower sex drive, erectile dysfunction, lack of energy, loss of muscle strength, moodiness and even depression. In some cases, the decline can be attributed to such factors as an injury to the testes, a pituitary gland issue, a history of cancer/radiation therapy, and/or a family history of stroke or heart attack. However, in many instances, the cause for this decline can be simply attributed to age. However, in most instances, the cause for this decline is idiopathic that is, we simply dont know.

Fortunately there are ways of addressing low testosterone for most men: testosterone replacement therapy (TRT). Offered by urologists and endocrinologists, TRT can take many forms: injections of testosterone cypionate (Depo-Testosterone) and testosterone enanthate can be done at home, usually bi-weekly, while those involving deep intramuscular injections of testosterone undecanoate (Aveed) are given at your providers office, usually every 10 weeks.

Note that Aveed is only available through your doctors office, clinic, or hospital, and therefore is not a medicine you can give yourself at home. You must also remain at the providers site for 30 minutes after injection so that the provider can watch for symptoms of POME or a serious allergic reaction. Symptoms of POME, or Pulmonary Oil Microembolism, include cough, difficult or labored breathing, chest pain, dizziness, and temporary loss of consciousness.

There are also a variety of topical creams, pills, nasal sprays application frequency varies widely and even implantable pellets, which involves your provider making a small incision, usually in the buttocks, every three to six weeks.

Quality of life usually improves within a few weeks, but the full effects of TRT can take three to six months. Patients tend to feel more energetic and can lose weight (with exercise and a proper diet), and see improvements in their sex drive. Pre-diabetic and diabetic patients can also benefit with improved insulin production.

However, there are side effects to consider. These can range from hair loss, acne and even breast enlargement to elevated red blood cell counts, changes in liver function, and in some cases cardiovascular issues, including heart attack and stroke. All of these will be discussed with your primary care physician and the TRT provider, and regular monitoring via blood and urine tests are necessary.

Interest in TRT continues to grow and, under the right circumstances, can make a very positive impact on ones quality of life physically, mentally and emotionally. Consult a provider to see if its right for you.

Dr. Aaron Hagge-Greenberg is a urologist and urologic surgeon at White Plains Hospital Physician Associates. For an appointment, call 914-949-7556.

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SARMs Before And After Results Real SARM Results And Users Review In 2022 – Outlook India

Posted: August 30, 2022 at 2:12 am

Whether you search for SARMs results 1 month or results after using them for a few months, we assure you these are some miraculous compounds that are recently proven to be more effective than anabolic steroids. SARMs results popularity has outgrown many bodybuilding supplements and this is because they can help pack on mass, ripped physique, and exhilarating strength in a faster manner.

Checkout Best SARMs Alternatives online that works without any side effects!

In this article, we will talk about the worlds best and most renowned SARMs for Bulking and Cutting. We will also point out multiple SARMs there are for female bodybuilders and those who simply want to lose weight using bodybuilding exercises.

What are SARMs?Recently, many people with no background in scientific studies asking are SARM a drug? This is in fact a fair question because SARMs have infiltrated bodybuilding and somehow managed to replace anabolic steroids.SARMs are actually Selective Androgenic Receptor Modulators, they do resemble to anabolic steroids structure wise but their binding capacity is what makes them different from them. SARMs are unlike steroids in bodybuilding which means they only act on selective receptors without alerting other biological processes in the body.SARMs are less risky than steroids because they do not convert into DHT or Estrogen which is the reason why many male bodybuilders get the side effects. In terms of testosterone suppression, SARMs only cause this phase for a shorter time than steroids which results in prolonged testosterone suppression for bodybuilders.

SARMs Before and After ResultsSome obvious changes/results that you can experience after the intake of SARM are mentioned below. Highlighted Muscle GrowthMost athletes and bodybuilders do take SARMs because they work like a magic for outrageous muscle mass growth. Most of them expect to gain over 30 pounds of lean muscle which they achieved within 4 months time frame, but for this legit SARM supplement with proper prescribed dosage shall be taken into account. For example, regular use of 20mg Ostarine considerably helps with muscle growth which has been experienced by thousands of bodybuilders in the US alone. Weight/Fat lossBest SARMs for fat burning is amongst the top searches on Google and this is because SARMs are capable of incinerating the fat reservoir in the body. Not the healthy fat but the lipids that your body has been storing for years. In recent days, SARMs are more preferred than Clenbuterol a steroid which is used to get rid of extra fat in the body because of less risk associated with Andarine, one of the best SARM for fat loss. Escalated StaminaWhat is the use of SARMs if not for improved stamina and physical power? Nearly every SARM works on physical power and maximized strength which is the demand of every athlete and sportsman. Under the right dosage, SARMs not only amplify the stamina in men and women but also keeps them energetic, focused, and alert throughout the day. Stops Muscle Wasting SyndromeMany bodybuilders during working out with peak performance tend to lose healthy muscle tissues which arent supposed to be this way. This will also accumulate the water content in muscles which gives your arms and chest a flabby appearance. SARMs allocate the muscle and hydro content in a suitable way that will stop muscle wasting. Faster and Superior Recovery against Muscle FatigueStudies have shown that SARMs long-term use makes the body endure the pain and pressure efficiently. SARMs improve the energy production in muscles which also makes them resistant to sprains, injury, and fatigue during the workout or in the outside world.

Bulking SARMS Before and After ResultsHere are the most effective SARMs for bulking in 2022 which are currently being used by bodybuilders and athletes to compliment muscle mass growth.1. Testolone (RAD140)2. Ligandrol (LGD-4033)3. Ibutamoren (MK 677)

Testolone RAD 140 SARM Before and After ResultsTestolone is regarded as one of the latest and potentially active SARM for muscle growth and bulking cycle. RAD 140 is still under many clinical studies and is not been approved by the FDA yet. Bodybuilders like Testolone so much because of the rapid results and it resembles a testosterone steroid.The main use of Testolone RAD140 is in chemotherapy patients whove lost significant muscle mass, this SARM is given to them for rapid recovery by halting the muscle degenerative disorder. Many physicians around the world refer to RAD 140 as an alternative to Testosterone Replacement Therapy (TRT).Speaking of Testolone results, a vast majority of its user reported elevated energy levels and significant improvements in muscle growth. The mechanism hints at escalated protein synthesis which is very beneficial for bulking workouts. Although RAD 140 results take some time occasionally the gains are reportedly permanent and more solid. With the use of RAD140, users tend to feel nauseated and have other symptoms very little.

The best way to take Testolone is by taking it for 60 days straight (if you are looking for 10-20 lbs muscle gain), but it also depends on the dosage of the compounds. For more remarkable results, Testolone is often combined with other SARM for bulking named Ligandrol.

Ligandrol LGD 4033 SARM Before and After ResultsIn 2022, a vast group of bodybuilders prefers Ligandrol for the best-looking body. The SARM is typically run for 12 weeks straight in a 10-20mg per day dosage after which you can expect to achieve 20 pounds of lean mass.First-time Ligandrol LGD 4033 SARM users take it in little dosage i.e. 6-10 mg for 6 weeks which is to experience a very little amount of side effects. As a suitable SARM for bulking cycle, Ligandrol is also being used for improved fat loss, the SARM binds to the androgen receptors located in the adipose tissues which tend to fasten the metabolism and this will lead rapid weight loss.Ligandrol is sometimes compared to Trenbolone because both compounds stimulate the production of trep muscles. Following a calorie-restricted diet and another regular workout, there are many results you can expect while using Ligandrol. Increased energy, sharpened focus, and lean abs are some of them.

Ibutamoren MK 677 SARM Before and After ResultsNot always a SARM but MK 677 sometimes referred to as Growth Hormone Secretagogue which produces growth hormone and protein in the body. In dire need of supplements, bodybuilders occasionally take Somatropin steroids for HGH stimulation but Ibutamoren is replacing the steroids as we know. Thats because very few side effects are associated with Ligandrol than Somatropin.Ibutamoren MK 677 SARM is the ideal compound for power-lifters who dont take no for an answer when it comes to showing their full body potential. You can also observe increased fertility while consuming Ibutamoren.In the latest reviews about Ibutamoren SARM, it was concluded that it may not be too much helpful to prevent muscle soreness and injury. It can shorten the muscle healing time but thats nothing compared to what Testolone RAD 140 does.In addition, the growth hormone stimulator like MK 677 aids peaceful and sound sleep which is another useful gimmick for muscle recovery. Ibutamoren users reportedly take a brief amount of sleep but they wake up feeling energetic and fresh like they have been sleeping for a day. You can experience the same Ibutamoren result but the condition is to take it in the evening. Stacking Ibutamoren is easy with other SARMs and the surprising part about the compound is there are no need for Post Cycle Therapy. In fact, some users take MK 677 SARM as a part of their PCT which is to replenish the dropped testosterone and HGH levels.Cutting SARM Before and After ResultsBest SARMs for Cutting in 2022 are reviewed by the experts on the reddit forum and other notable platforms online. Some of these SARMs are perplexedly made but the science justifies the results.

Cardarine Before and After ResultsMany reviews about Cardarine GW-501516 SARM say its not a proper SARM but rather a PPAR receptor agonist. The function of such molecules is to provide the fat-burning effects to the body by burning fats and not glucose entirely. The fat cells fulfill the energy demands more efficiently than glucose does and by this, we mean better muscle definition and improved stamina ahead.Cardarine is used by exceptional types of bodybuilders who want to build an ethos out of themselves. GW 501516 tells us about the eradication of stubborn fat from the belly, only 15mg daily dosage for 8 weeks is sufficient for the desired results. You can see at the end of the first month that your body begins to react to strenuous workouts and that it also loses around 5% of body fats.Most people in 2022 are looking for a supplement that can help them shrink their love handles, after spending a sedentary lifestyle most of us get determined to the workout that only stays for a few days. SARMs like Cardarine is the name of the game when you keep wanting to be dedicated and punctual to the workout without any compunction for laters.

Ostarine Before and After ResultsAn athletic physique means you will develop cuts as well as muscle mass which is a pleasant sight for the viewers. With the help of the Ostarine cycle, many users reportedly gained over 8 pounds of lean muscle mass but they also get immense energy levels that help them with fat eradication.Ostarine cycle results in improved bone density, and insulin resistance and it does not interfere with the hormonal system. Many steroids and SARMs end up disturbing the levels of Testosterone, Progesterone, Growth Hormones, and Estrogen but Ostarine is exempted from all those nasty side effects.Ostarine is considered the mildest SARM which means its also safer than most bodybuilding SARMs available in 2022. So many clinical trials are already done on Ostarine and its awaiting FDA approval, there are fewer side effects than any other SARMs. You can take Ostarine in conjunction with RAD 140 Testolone or Ligandrol but you have to be punctual during the workout sessions.

Stenabolic SR9009 SARM Before and After ResultsStenabolic SARM is an ideal SARM for every type of body whether endomorphs or ectomorphs, the SARM is greatest in fat eradiation while replacing them with healthy muscle mass. Recently, the SR9009 Stenabolic cycle has taken a new turn in which bodybuilders are taking it as a weight loss supplement.Stenabolic is indeed a REV-ERB agonist which means it manages and regulates a special type of protein called REV-ERB. This protein is located throughout the body, especially in the muscle tissue, upon activation the regulation of fat metabolism and energy generation takes place and this turns the user into a more energetic, result-oriented, and literally a beast in the gym.Stenabolic is the best SARM for females in order to accomplish their weight loss goals. Different men and women athletes are getting fond of gene expression effects of Stenabolic which seems to increase the mitochondrial energy in each muscle cell. Mitochondria are frequently referred to as the "powerhouses" of cells because they produce most of the cell's energy. Therefore, by increasing the number of mitochondria in muscle cells, Stenabolic SR9009 may help a woman's muscles to produce more energy and become stronger.

Conclusion - Are SARMs Before and After Results Real?You have the liberty to not believe what they say about mere bodybuilding supplements, but SARMs or steroids are not just any other bodybuilding supplements. It took years of research and critical studies to define them and make them available in the consumer market. Just like the SARMs results, SARM side effects are also real which takes a heavy toll on the body at times.To avoid such outcomes, you may start with the minimum dosage of any SARM that you have chosen, also make sure to stick with a healthy diet plan and workout session which gets the most out of the SARMs before and after results.(Disclaimer : The above is a sponsored post, the views expressed are those of the sponsor/author and do not represent the stand and views of Outlook editorial.)

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Woman shares the frustrations of going through menopause at age 49 – Insider

Posted: August 30, 2022 at 2:07 am

It seems unreal when I think about how perimenopause crept in quietly without too much fanfare in my late 30s and early 40s. It wasn't too bad I had minor symptoms but it was bearable.

Then all of a sudden, in 2018, after my menstrual cycle abruptly ended at 46, menopause became my living nightmare. It crept up and consumed me. I slid slowly into an abyss of unexplained joint pain, hot flashes, brain fog, exhaustion, a nonexistent libido, and depression.

If I could advise young women of anything, it would be to avoid menopause. But sadly, that's not a reality. Fatigue, night sweats, osteoporosis, hot flashes, sweating, insomnia, dryness, anxiety, irritability, low libido, moodiness, and vaginal dryness that is my everyday reality with menopause.

All these symptoms converging at once meant my day-to-day life changed a lot. I was either in too much pain or too exhausted to work, socialize, or do much of anything. My world got smaller as I withdrew from activities and things I once enjoyed.

I was falling behind on work, missing deadlines, and going days without doing anything, as I usually used any energy reserves I could muster to deal with family-related issues. I tried to ensure that my husband and kids felt supported even as I grew worse each day.

I barely slept more than two or three hours a night, increasing my brain fog and fatigue. I was battling migraines daily and staring at a reflection in the mirror I didn't recognize. My body had turned on me and left me wondering whether I faced death or institutionalization first.

My husband is nine years younger than me and still has a high libido. That was a massive plus during the peri phase because my libido was also in overdrive. The decline began once I hit menopause; my libido was almost nonexistent.

Painful intercourse can be a dealbreaker for many women, and vaginal dryness is a real issue. But I was determined for it not to break me.

I didn't want to be the discarded middle-aged wife whose younger husband decided that working through menopause was too much effort.

We still had sex regularly, as I was intent on keeping the dream alive despite my lack of arousal. I was willing and able, so I did. I still found my husband attractive and wanted to continue our robust sex life, so I used what little I had left in the tank to ensure we kept that connection going.

Enter, lube; all kinds of lube. We've tried them all with varying degrees of success. It took lots of trial and error to settle on one we both liked. Adding lube made it easier for me to transition into this new version of our sex life.

In May 2022, I reached my breaking point. I realized that using any scrap of sanity or energy I had on others couldn't continue. It became unsustainable for me, my husband, our family, or our business.

I made an appointment with my doctor and my therapist to explore options. After lots of tears, tests, and bloodwork, I began taking bioidentical hormone-replacement therapy, or BHRT, at the end of June.

To say that the change has been life-giving is an understatement. I'm now a month along, and my symptoms have almost vanished. The most bothersome like hot flashes and daily migraines left immediately. The other symptoms dryness, brain fog, lack of sleep, joint pain, and low energy have steadily improved each day.

I don't know that BHRT is for everyone, but it was the right choice for me. The turmoil that menopause can create in a woman's life is scary. The fear of becoming a statistic is gone, and I have my life back and no longer worry about disappointing my family and friends.

Cindy Rodriguez Constable is a communication strategist, freelance journalist, and professional speaker.You can follow her here.

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Hot Flashes Can Impact Up to 80% of Women So Why Arent We Talking About It? – SheKnows

Posted: August 30, 2022 at 2:07 am

Many women have hot flashes, which can last for many years after menopause, according to the National Institute of Aging. In fact, up to 80 percent of women will experience hot flashes associated with menopause. These are known as vasomotor symptoms (VMS), which are characterized as sudden and intense sensations of heat throughout your body. It may be accompanied by sweating, reddening of the skin, chills, and rapid heartbeat. Hot flashes can also be mild or strong enough to wake you up (called night sweats). Most hot flashes last between 30 seconds and 10 minutes and can happen several times an hour, a few times a day, or just once or twice a week.

Despite the prevalence of hot flashes, and the number of people who undergo menopause (an estimated 1.3 million women in the U.S. alone enter menopause every year), theres still a negative stigma associated with it. As a result, women arent receiving the proper care or attention to address the symptoms associated with menopause, which also include vaginal dryness, mood changes, sleep problems, weight gain, and slowed metabolism to name a few. So, why is there a stigma surrounding it? The short answer is that menopause makes women feel old, undesirable, and invisible, saysDr. Tara Allmen, Board Certified Gynecologist in NYC and Author of Menopause Confidential. And thats why theres a level of shame associated with it and its symptoms.

In addition to the stigma associated with menopause, VMS can also impact many aspects of womens lives, including sleep, the ability to focus, and personal relationships. The most common symptom in menopause that 80% of women will endure are hot flashes and night sweats, says Dr. Allmen. This will lead to poor sleep and therefore increase fatigue, foggy brain, and affect their mood while diminishing their interest in sex. Vaginal health will be affected. Their vaginas will become drier so sex will become painful. Their interest in making good lifestyle choices will also decrease, which will impact their weight.

There are a lot of myths surrounding menopause, one being that life (and your sex life) is over, which is simply not true. One of the greatest misconceptions surrounding menopause is that life is over or that youll never have great sex again, says Dr. Allmen. Theres also the idea that youll never be able to lose weight, that youre old, or that youll never feel like yourself again. Its understandable that youll be going through an array of emotions during this time, but one thing to remember is that being in your 40s or 50s does not make you old. There are an array of women in their 50s who have never looked better and when you think about what comes after menopause such as no periods (this also means no PMS symptoms) and less pelvic pain, it can give you a new outlook on this next life phase.

Another misconception is that yes, hot flashes may be a nuisance, but thats okay. Theyre not just a nuisance, says Dr. Mary Jane Minkin, a clinical professor in the Department of Obstetrics, Gynecology, and Reproductive Sciences at the Yale University School of Medicine. There are studies that show that hot flashes can be associated with increased risks of heart disease, bone loss, or all these other things that can go along with menopause and thats why we dont want to ignore them.

Another reason there seem to be fewer people talking about menopause and its symptoms is because there are fewer doctors treating it, according to Dr. Minkin. The culprit? In 2002, the Womens Health Initiative study was released, which showed that hormone replacement therapy had more detrimental than beneficial effects. This essentially led to a mistrust of hormone therapy and estrogen among women.

A lot of obstetrics and gynecology residency programs in the United States stopped teaching menopause management, says Dr. Minkin. If you had anybody who trained in obstetrics and gynecology finishing their residency less than 20 years ago, they werent trained in menopause, so they learned nothing about medical management. She adds, Its not their [the students] fault, but we have a lot of people suffering because of it. Dr. Minkin does offer some good news, however. Hot flashes do tend to get better over the course of time, she says. Its not instantaneous, and the average duration of hot flashes is about 7.4 years, but it does tend to get betterits not 7.4 years and misery for most people.

There havent been a lot of medical breakthroughs for hot flashes in the last 20 years, but Dr. Minkin says thats about to change. Estrogen has certainly been the mainstay of therapy and it still worksits an excellent remedy for hot flashes, she says. There are some herbal/over-the-counter, non-hormonal medications and alternative therapies which can be helpful. She adds, There is also a brand new drug coming out. Its non-estrogenic and works extremely well. We are hoping that will be available this coming year. A major misconception is that there are no treatments for hot flashes. There may have been a time when it was brushed off by doctors, but we can come up with concoctions and combinations which can really be quite helpful to women symptomatology-wise, says Dr. Minkin.

In order to end the stigma, we need to encourage and empower women to take charge of the rest of their lives. Lets give everyone permission to say aloud, I need help. I dont feel well,' says Dr. Allmen. This is a normal part of life that we need to talk about. If all women had the what to expect when youre not expecting talk at the age of 40 to help them understand the journey ahead of perimenopause and menopause, they would be less confused, less fearful, less miserable, and know what choices are available, whether lifestyle or medication, to help them have an easier time with the transition and find symptom relief.

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Hot Flashes Can Impact Up to 80% of Women So Why Arent We Talking About It? - SheKnows

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F*cking Ridiculous! Scotland Is Championing Menopause But Got One Big Thing Wrong – Suggest

Posted: August 30, 2022 at 2:07 am

Scotland recently made a huge move to bring awareness and resources to womens health issuesincluding menopause. At first blush, it sounds great. But a snag in the execution made a lot of people unhappy.

Scotlands Period Products Act is a groundbreaking piece of legislation to educate the public to normalize conversations about menstruation and menopause, plus provide sanitary products free of charge.

The legislation also created the position of period dignity officer to promote and be the face of the new program. And this is where the criticisms begin: Scotlands first period dignity officer is a man named Jason Grant.

RELATED: Hormone Replacement Therapy Will Be Available Over-The-Counter In The UK In SeptemberWe Wish the U.S. Would Follow Suit

As a resultand to the surprise of no onethe public, along with several celebrities, criticized the move. Tennis legend Martina Navratilova was particularly vocal.

Have we ever tried to explain to men how to shave or how to take care of their prostate or whatever?!? This is absurd.

She later added, Does he menstruate? I somehow doubt it.

Grant is a former personal trainer and tobacco salesman who now has the job of promoting access to free sanitary products in schools and colleges across the Scottish Tay region. His job description also includes discussing issues around periods and menopause. The question is: why?

Grant and Scottish officials say having a man in the position will help break down barriers, reduce stigma, encourage more open discussions, and normalize topics like menstruation and menopause.

Unfortunately, it also sounds a lot like mansplaining.

Susan Dalgety, a columnist for The Scotsman, told Sky News, its great that Scotland is the first country in the world to offer free period productsBut I am astonished that a man has been appointed to be lead on period dignity in Tayside. It takes mansplaining to a new level.

Grant also chose an unfortunate shirt to wear for his press photos.

Jason has said being a man will help him reduce stigma and that it is time to normalize topics like menstruation and menopause, Dalgety added. Periods are normal life for women, we dont need some bloke in a blood red polo shirt raising our awareness.

Most girls dont feel comfortable talking about their periods with male friends or their fathers, Dr. Beth Wallace pointed out. So, why would they put a man in charge of this conversation?

The organization was created to ensure every woman had access to free sanitary products and bring awareness to menopause, and we are pumped that Scotland is leading the charge. But, it should be a team of women working on this project. Placing a man in charge is simply tone-deaf.

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F*cking Ridiculous! Scotland Is Championing Menopause But Got One Big Thing Wrong - Suggest

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Hunter Schafer Criticized For Appearing to Agree With Anti-Nonbinary Post – Newsweek

Posted: August 30, 2022 at 2:07 am

Hunter Schafer is facing backlash on social media for appearing to agree with an Instagram post about transmedicalism and the cutting of HRT (hormone replacement therapy) in certain states.

The Euphoria star and trans activist, 23, seemingly wrote on a post shared to Instagram last week by user @piggytaiwan about trans healthcare and how the non-binary community could be affecting trans people from receiving medical treatment.

The post also said that non-binary trans people are contributing to laws in certain states that no longer regard HRT and gender-reaffirming surgery as medically necessary procedures.

Earlier this month, Florida began a rule-changing process to ban gender-affirming care for trans youth in the state.

This school of thought is known as transmedicalism, namely that being transgender is dependent upon experiencing gender dysphoria or requiring medical treatment to transition.

It is also often referred to as "truscum", which is defined as: a person who believes that gender dysphoria is an essential trait to being transgender.

In the original post, @piggytaiwan wrote in part: "Y'all couldn't stand to let binary trans people be the voice of this community," and, "That means more trans people will have to pay for their transition out of pocket, forcing more of us into sex work."

The post was criticized on social media, but fans noticed that Schafer had commented "!!!!!!" seemingly in agreement. Several people have now called out the actress and model on Twitter.

"hunter schafer blaming nb ppl for the things happening to trans ppl's healthcare is so f****** sickening. girl that is what conservatives want!! they wanna divide you by making these horrific f****** laws and pitting queer n trans ppl against each other!! don't b a transmed!!" reads one tweet.

Another Twitter user wrote: "Who's gonna tell hunter schafer that the real enemy are cis transphobes and not nonbinary people."

While another tweeted: "Hunter Schafer blaming trans ppl for their own oppression instead of the bigots that call the shots and make the laws is really funny and sad at once. I promise u tiktok teens have 0 hand in passing transphobic medical laws."

Schafer has long been a vocal advocate for trans rights and, in 2016, signed on as a plaintiff in the lawsuit from the ACLU (American Civil Liberties Union) against North Carolina's bathroom bill.

Schafer wrote in a 2017 op-ed for i-D magazine: "As a transgender teenager who grew up in North Carolina, navigating bathrooms on my own was an extremely difficult journey, particularly at public school.

"In early high school (during a more primary stage in my transition), I felt safer using the women's restroom and locker room. But I was often met with compromises, like being told to use a staff bathroom or the men's room, which was basically a sentence to eternally hold it in," Schafer wrote. "I felt like an outlaw every time I had to pee, as if this natural bodily function were some unforgivable act."

North Carolina's anti-trans bathroom bill was partially repealed in 2017.

Newsweek has contacted Schafer's representatives for comment.

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Hunter Schafer Criticized For Appearing to Agree With Anti-Nonbinary Post - Newsweek

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Gender Dysphoria Is Now Protected Under the Americans With Disabilities Act and It’s a Pretty… – POPSUGAR

Posted: August 30, 2022 at 2:07 am

In recent years, conservative politicians have made extreme efforts to restrict access to gender-affirming care. In one example, they directed state health agencies to treat gender-affirming care for trans minors as "child abuse." In another case, they required middle school and high school athletes to show proof of their assigned sex at birth. Most recently, they prohibited discussion of gender identity and sexual orientation in the classroom. But last week, a landmark federal law may have helped set a precedent that could protect transgender people who experience gender dysphoria.

On Aug. 24, a panel of the Fourth US Circuit Court of Appeals announced the decision that the 1990s Americans with Disabilities Act (ADA) extends to people with gender dysphoria. This effectively reversed the federal ruling in Kesha Williams v. Stacey Kincaid, where Williams, a transgender woman, sued the Fairfax County sheriff in Virginia for intentionally misgendering her and housing her in a jail with men. (The court originally ruled against Williams.)

By acknowledging gender dysphoria under the ADA, it sets a precedent that gender-affirming treatments should be a part of standard medical care. Yet with gender-affirming care like hormone-replacement therapy under attack, it's more important than ever to better understand what gender dysphoria is, how the ADA can protect trans people, and why this ruling is a huge win for human rights.

Gender dysphoria is a health condition listed in the Diagnostic and Statistical Manual of Mental Disorders (DSM) that is categorized as "psychological distress." It's what happens when a person's assigned sex at birth does not align with their gender identity, creating feelings of anguish and intense emotional pain. And though gender dysphoria's diagnosis in the DSM makes it easier for some transgender people to access medical care by acknowledging it as an actual health condition, it can also be controversial. Some people argue that it pathologizes gender dissonance and contributes to the stigma that being trans is a "mental illness," which is not the case.

Regardless, it's important to note that not every transgender person experiences dysphoria, and it varies in severity from person to person. In the case of Kesha Williams vs. Stacey Kincaid, Williams experienced gender dysphoria when she was intentionally misgendered and denied hormone treatment, in addition to being housed in jail with men.

The Americans with Disabilities Act was established to prohibit discrimination against anyone with disabilities in areas of employment, transportation, public accommodations, communications, and access to state and local government programs and services, according to the US Department of Labor. The ruling states, "The ADA defines the term 'disability' broadly to include 'a physical or mental impairment that substantially limits one or more major life activities of such individual."

The reason gender dysphoria now falls under the ADA is because the ruling acknowledges it as a disability. The federal court ruled the 1990 landmark federal law protects transgender people who experience symptoms as a result of dissonance between their sex assigned at birth and their true gender identity. This will set a precedent that can be used to challenge laws attempting to restrict access to medical care and other areas that fall under the ADA, like employment and government benefits.

The federal ruling means that gender dysphoria is covered under the Americans with Disabilities Act. The decision applies broadly to all areas of society covered by disability-rights law, including employment, government benefits and services, and public accommodations. In addition to destigmatizing a legitimate health condition, AP News reports that the ruling provides legal protections to people with gender dysphoria in Maryland, North Carolina, South Carolina, Virginia, and West Virginia, and it may serve as a legal precedent for other states.

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