Page 2,803«..1020..2,8022,8032,8042,805..2,8102,820..»

Entest BioMedical Excited With Progress on 10 Dog Pilot Study of "Universal Donor" Stem Cell Treatment for Canine …

Posted: March 21, 2012 at 12:52 pm

SAN DIEGO, CA--(Marketwire -03/21/12)- Entest BioMedical Inc. (OTCQB: ENTB.PK - News) (Pinksheets: ENTB.PK - News)

Entest BioMedical Inc. (OTCQB: ENTB.PK - News) (Pinksheets: ENTB.PK - News) and RenovoCyte LLC announced they have treated 8 canine patients of a 10 dog pilot study utilizing Canine Endometrial Regenerative Cells (CERC) licensed from Medistem Inc. (Pinksheets: MEDS.PK - News) in the treatment of canine osteoarthritis.

Previously, Entest announced the treatment of the first canine patient on November 18, 2011. Since that time Entest's McDonald Animal Hospital has treated 8 dogs in its 10 Dog Pilot Study with RenovoCyte. To date, all of the dogs participating in this study have shown dramatic improvement in their mobility and apparent reduction of pain.

Dr. Greg McDonald, Chief Veterinarian at McDonald Animal Hospital, said, "50 million CERC stem cells have been injected intravenously into eight dogs. Each dog selected for this study showed signs of arthritis. Follow-up blood tests, urinalysis and physical exams are now being scheduled for the patients that have already been treated. So far, all these canine patients have shown improvement."

Entest BioMedical Chairman David Koos stated, "Osteoarthritis is considered one of the most common causes of lameness in dogs, occurring in up to 30% of all dogs. It is caused by a deterioration of joint cartilage, followed by pain and loss of range of motion of the joint. We expect this treatment to relieve these animals from the pain associated with arthritis. This has extraordinary possibilities for dogs and may lead the way for human treatment of arthritic pain."

The CERC is a "universal donor" stem cell product that does not require matching with the recipient allowing for the generation of standardized products that can be delivered to the office of the veterinarian ready for injection. This is in stark contrast to current stem cell therapies utilized in veterinary applications which require the extraction, manipulation, and subsequent implantation of tissue from the animal being treated. CERC is the canine equivalent of Medistem's Endometrial Regenerative Cell (ERC). Medistem was recently granted approval from the FDA to initiate a clinical trial in human patients using its ERCs.

"We are extremely pleased with our research relationship with Entest BioMedical. This study of canine pets suffering from naturally occurring osteoarthritis is a better test model than laboratory induced disease because it will give us the opportunity for long term follow up of these patients. RenovoCyte sees this study as part of the supporting documentation that will be needed to obtain FDA approval for widespread usage of this therapy," said Shelly Zacharias, DVM, Director of Veterinary Operations, RenovoCyte, LLC.

A spokesperson for Entest noted the Company is also currently conducting a 10 dog safety study on its immune-therapeutic cancer vaccine for dogs, having treated 3 dogs so far.

About Entest BioMedical Inc.:Entest BioMedical Inc. (http://www.entestbio.com) is a veterinary biotechnology company focused on developing therapies that harness the animal's own reparative / immunological mechanisms. The Company's products include an immuno-therapeutic cancer vaccine for canines (ImenVax). ImenVax is less invasive and less traumatic in treating cancer. Additionally, the Company serves as the contract research organization conducting a pilot study on a stem cell based canine osteoarthritis treatment (developed by RenovoCyte LLC) utilizing a 'universal donor' stem cell. Entest is also building a network of veterinary hospitals (with its initial location in Santa Barbara, CA and anticipates acquiring other veterinary hospitals in California) -- which serve as distribution channels for its products.

DisclaimerThis news release may contain forward-looking statements. Forward-looking statements are inherently subject to risks and uncertainties, some of which cannot be predicted or quantified. Future events and actual results could differ materially from those set forth in, contemplated by, or underlying the forward-looking statements. The risks and uncertainties to which forward-looking statements are subject include, but are not limited to, the effect of government regulation, competition and other material risks.

Follow this link:
Entest BioMedical Excited With Progress on 10 Dog Pilot Study of "Universal Donor" Stem Cell Treatment for Canine ...

Posted in Stem Cell Therapy | Comments Off on Entest BioMedical Excited With Progress on 10 Dog Pilot Study of "Universal Donor" Stem Cell Treatment for Canine …

2nd Lee Co. doctor's license restricted in stem cell case

Posted: March 21, 2012 at 4:28 am

2nd Lee Co. doctor's license restricted in stem cell case

FORT MYERS, Fla.- Another Lee County doctor is caught in the center of a stem cell controversy. The State Department of Health has issued an emergency license restriction to Dr. Konstantine Yankopolus, a general practitioner.

Dr. Yankopolus is still allowed to practice general medicine and is treating patients. The license restriction mandates he can't do anything involving stem cell treatment.

It's business as usual at his office on Colonial Blvd.

The doctor is still treating patients, but an emergency order issued from the Florida Department of Health, Monday prevents him from doing anything with stem cells.

The order says Dr. Yankopolus' license "is hereby immediately restricted from providing, collaborating, facilitating, procuring, referring or advising on any stem cell treatment."

The action comes after the state suspended the license of his colleague, Dr. Zannos Grekos' earlier this month.

The emergency order says Dr. Yankopolus helped Dr. Grekos perform stem cell therapy on the late Richard Polling despite knowing the Bonita Springs cardiologist was not allowed to do such a procedure.

The state Surgeon General alleges, Dr. Yankopolus falsified Polling's records.

He writes, "Subsequent to the death of patient R.P., Dr. Yankopolus entered a false medical progress note in R.P.'s chart falsely indicating that no stem cell preparation was infused."

See the original post here:
2nd Lee Co. doctor's license restricted in stem cell case

Posted in Stem Cell Therapy | Comments Off on 2nd Lee Co. doctor's license restricted in stem cell case

Cell-in-a-Box® Encapsulation Technology Creates Extensive Applications within the Stem Cell Arena

Posted: March 21, 2012 at 4:28 am

SILVER SPRING, Md.--(BUSINESS WIRE)--

Nuvilex, Inc. (OTCQB:NVLX), an emerging biotechnology provider of cell and gene therapy solutions through its acquisition of the SG Austria assets, today discussed the value of encapsulation, freezing, storage, survivability and localization of human stem cells once implanted using the proprietary Cell-in-a-Box technology.

The encapsulation of human stem cells is enabled by the Cell-in-a-Box technology, which can then be frozen, stored and later implanted into target tissues. The benefits of encapsulation are several: first, the process allows for freezing of stem cells for long-term storage without appreciably affecting viability. Second, encapsulation protects the stem cells from stress factors caused by direct aeration and sheer forces associated with bioreactors. Third, Cell-in-a-Box encapsulated stem cells are held in place at the site of implantation, maximizing their potential efficacy as they have the potential to stimulate growth of surrounding new, healthy tissue. Finally, encapsulated cells may prevent any potential side effects associated with direct injection since they remain localized to the area of treatment when encapsulated.

Dr. Robert Ryan, Chief Executive Officer of Nuvilex, commented, For many years it was assumed stem cells existed only to replace cells that had died or were damaged. Recent studies suggest factors stem cells secrete provide signals to surrounding tissue that can stimulate regeneration. The potential therefore, is that if stem cells can be maintained at a particular site where damaged, removed or non-functional tissue was through some sort of holding mechanism, this may aid in a positive growth response in that tissue. In addition, the stem cells themselves have the potential to undergo development into the appropriate cell type at that location, potentially creating miniature organs. The Cell-in-a-Box technology is designed specifically for those purposes. Thus, encapsulated stem cells would be implanted and remain in place, ultimately being able to serve a broad number of medical applications entirely dependent on where in the body they are placed.

About Nuvilex

Nuvilex, Inc. (OTCQB:NVLX) is an emerging international biotechnology provider of live clinically useful, therapeutically valuable, encapsulated cells, as well as services for encapsulating live cells for the research and medical communities. Through substantial effort, the aspects of our corporate activities alone and in concert with SG Austria continue to move toward agreement completion and ultimately a strong future together. Our companys ultimate clinical offerings will include cancer, diabetes and other treatments using the companys industry-leading cell and gene therapy expertise and cutting edge, live-cell encapsulation technology.

Safe Harbor Statement

This press release contains forward-looking statements within the meaning of the Private Securities Litigation Reform Act of 1995 involving risks and uncertainties, including product demand, market competition, and Nuvilexs ability to meet current or future plans which may cause actual results, events, and performances, expressed or implied, to vary and/or differ from those contemplated or predicted. Investors should study and understand all risks before making an investment decision. Readers are recommended not to place undue reliance on forward-looking statements or information. Nuvilex is not obliged to publicly release revisions to any forward-looking statement, to reflect events or circumstances afterward, or to disclose unanticipated occurrences, except as required under applicable laws.

More here:
Cell-in-a-Box® Encapsulation Technology Creates Extensive Applications within the Stem Cell Arena

Posted in Stem Cell Therapy | Comments Off on Cell-in-a-Box® Encapsulation Technology Creates Extensive Applications within the Stem Cell Arena

NeoStem Provides Updates and Reports Year End Results

Posted: March 20, 2012 at 3:51 pm

NEW YORK, March 20, 2012 (GLOBE NEWSWIRE) -- NeoStem, Inc. (NYSE Amex:NBS) ("NeoStem" or "the Company") is a leader in the cell therapy industry, developing cell based therapeutics supported by the Company's expertise in contract manufacturing. This strategic combination and depth of experience in cell therapy development and manufacturing provide NeoStem with unique capabilities to develop its own cell therapies and that sets the Company apart from others in the cell therapy landscape. 2011 represented a major year of strategic transition for NeoStem, and the Company plans to build upon that in 2012 and in the years ahead.

NeoStem reported its audited results for 2011. Consolidated revenues for the year ended December 31, 2011 were $73.7 million compared to $69.8 million for 2010. The Company's consolidated net loss for 2011 was $56.6 million, which included $10.3 million of non-cash equity-based compensation expense, $19.4 million of goodwill impairment charges and $9.0 million of depreciation and amortization. Overall, the Company's consolidated cash loss for 2011 was $15.5 million (see reconciliation below). Net loss attributable to NeoStem common shareholder interests for 2011 was $47.8 million, or $0.54 per share.

As of December 31, 2011, the Company had consolidated cash and cash equivalents of $12.7 million, and an additional $2.5 million in cash held in escrow (classified in Other Assets).

NeoStem believes that the opportunities that exist today in cell therapy are robust and growing despite a persistently difficult financial environment, making this an opportunistic time to pursue the monetization of the Company's 51% ownership of Suzhou Erye Pharmaceutical Co., Ltd. and bolster its cell therapy business. In June 2011, the Company engaged a financial advisor to lead the effort to pursue the possible divestiture of the Company's interest in Erye. Marketing efforts are underway and have generated interest from both financial and strategic buyers.

On the therapeutics side of the business NeoStem now has a pipeline of assets that includes Amorcyte (Phase 2 trial for preservation of heart function after a heart attack), Athelos (physician sponsored Phase 1 trials for a range of auto-immune conditions) and pre-clinical development work on its VSEL(TM) technology. The Company's most advanced asset is AMR-001 for the treatment of acute myocardial infarction for which enrollment for a Phase 2 study in the United States commenced in January. The study is a multicenter, randomized, double-blind, placebo-controlled clinical trial to evaluate the safety and efficacy of infarct-related artery infusion of AMR-001, an autologous bone marrow derived cell therapy enriched for CD34+ cells. AMR-001 is administered 5 to 11 days post-stent placement in patients diagnosed with an ST segment elevation myocardial infarction ("STEMI") with ejection fraction less than or equal to 48%. The study will include 160 subjects, age 18 and older, randomized 1:1 between treatment and control. The manufacturing, product supply, and logistics for the trial will be supported by Progenitor Cell Therapy, LLC, NeoStem's contract manufacturing company.

Amorcyte currently has ten activated clinical trial sites for its Phase 2 AMI clinical trial with the initial patients enrolled. Trial enrollment is expected to be completed in approximately one year with data read out six months following the last treated patient. The Amorcyte franchise is supported by a strong patent portfolio which includes both composition of matter and methods of treatment around use of these hematopoietic stem cells for treatment of cardiac ischemia and other ischemic tissue that result from vascular insufficiency. The Company sees Amorcyte as a pipeline of therapeutics with potential in multiple indications from STEMI to congestive heart failure and other related vascular insufficiencies. The Amorcyte product addresses both an unmet medical need and a large potential market.

"One of the most important attributes of AMR-001 is that it's 'natural.' We are enhancing the body's normal and natural response to ischemic injury," said Dr. Robin Smith, CEO of NeoStem. "Ample historical evidence, published literature and our own compelling Phase 1 data give us confidence that this product will ultimately make it to the marketplace. Our next most advanced asset is held by Athelos Corporation, (a NeoStem company, partnered with Becton, Dickinson and Company) which is developing a novel T-cell platform for immunological disorders. The Athelos T-cell technology represents an innovative approach to restoring immune balance with potential applications in graft vs. host disease (GvHD), solid organ transplant (SOT) and autoimmune diseases, such as asthma and diabetes. Multiple physician sponsored phase 1 studies are expected to report results that will be used to determine the direction of clinical development.

"NeoStem is also developing pre-clinical assets, including its VSEL(TM) Technology platform for regenerative medicine, which NeoStem believes is an endogenous pluripotent non-embryonic cell that has the potential to change the paradigm of cell therapy as we know it today. These activities have received awards in excess of $2.5 million which funds support the work of prestigious researchers who are pioneering this science with NeoStem.

"Behind the development of these therapeutic assets is the NeoStem cell therapy contract manufacturing business (PCT) which itself continues to grow. New clients have engaged PCT to assist them in the development of their products, including a global, diversified healthcare company who recently selected PCT to provide stem cell processing in our two GMP manufacturing facilities in the United States (California and New Jersey). PCT's prominence in the marketplace continues to grow and that is reflected by both client satisfaction and the revenues the company generates.

"As we look to the year ahead, we are excited on multiple fronts. Our capital preservation efforts are now bearing fruit as our cash burn rate is in-line with our peers. We expect to continue to carefully invest our capital in projects that meet our internal rate of return hurdle and risk parameters. We believe the PCT and Amorcyte acquisitions have created true value for our shareholders and we look forward to demonstrating that as these assets reach their respective value inflection points. We see the unmet medical need in cardiology and the treatment burden associated with chronic diseases as representing a significant challenge to modern society. We believe that cell therapy holds many of the solutions to the health crisis that societies face and have the potential to create real pharmacoeconomic benefit as well as shareholder value for our company.

Continued here:
NeoStem Provides Updates and Reports Year End Results

Posted in Cell Therapy | Comments Off on NeoStem Provides Updates and Reports Year End Results

Moraga Announces Issuance of Adult Stem Cell Patent for Humans

Posted: March 20, 2012 at 1:27 pm

LOS ANGELES--(BUSINESS WIRE)--

Moraga Biotechnology Corporation, an adult stem cell company based in Culver City, California, announces the publication of its blood-derived Blastomere-Like Stem Cells (BLSCs) patent with the European Patent Office (EPO). The EPO had previously granted the patent of the Companys non-embryonic totipotent blastomere-like stem cell on May 19, 2011 in which the English claims were erroneously limited to rat stem cells. This error was corrected in the republished EP17895540B9. The EP17895540B9 claims isolated mammal/human post-natal blastomere-like stem cells and isolation methods.

Moragas chief executive, Dr. John F. Wong, noted: We are very pleased to have the EPO grant the 540 patent as Moraga and its U.K. partner, Pharmacells, Ltd. achieved a major milestone validating its adult stem cell technology. Moraga is particularly indebted to its patent counsel, Fish and Associates (Irvine, CA) for its fine work in prosecuting its patents both in Europe and currently in the United States with the U.S. Patent and Trade Office (USPTO).

For more information on Moraga Biotechnology Corp. please visit http://www.moragabiotech.com.

Excerpt from:
Moraga Announces Issuance of Adult Stem Cell Patent for Humans

Posted in Stem Cell Videos | Comments Off on Moraga Announces Issuance of Adult Stem Cell Patent for Humans

9/11 Search And Rescue Dog Gets Stem Cell Treatment

Posted: March 20, 2012 at 1:27 pm

BURKE, Va. (WUSA) -- Red, a black lab from Annapolis, has spent the last ten years as a search and rescue dog. Her missions have included Hurricane Katrina, the La Plata tornadoes, and the Pentagon after 9/11.

"The search and rescue dogs at the Pentagon are credited with finding 70% of the human remains," said Heather Roche, Red's owner and handler. "That helped a whole lot of those families actually get closure."

At just under two years old, 9/11 was Red's first search. Today, she's one of the last 9/11 search and rescue dogs still alive. She retired last July due to severe arthritis.

"The last few months, she would like to be a couch potato but she can't even get on the couch any more," said Roche. "It would be nice if she could do those kinds of things that she misses."

Roche brought Red to the Burke Animal Clinic for stem cell regenerative therapy compliments of MediVet America, the company that developed the in-clinic stem cell technology.

"This is a small something that we can give back as a way of saying thanks for what you guys have done for us," said Dr. John Herrity at the Burke Animal Clinic. "We are just taking fat from Red's side and then we are going to spin it down, process it, extract the stem cells from there."

Red received her first injection just a few hours after she woke up from surgery. The rest of her extracted stem cells will be stored free of charge for use in follow-up treatments.

"We've done about 28 dogs and of those dogs we've had about 75-80% of them doing very well," said Dr. Herrity.

Two other 9/11 dogs that recently received the same stem cell therapy are able to run, climb, and play again. Dr. Herrity's own dog, Bradley, is living proof that the treatment works. Bradley received the same stem cell treatment about one year ago and he's made great progress.

"Hopefully in about 2-3 months, she will be more comfortable, moving around, wanting to play more," said Dr. Herrity.

Link:
9/11 Search And Rescue Dog Gets Stem Cell Treatment

Posted in Stem Cell Treatments | Comments Off on 9/11 Search And Rescue Dog Gets Stem Cell Treatment

Hamilton Thorne Launches XYRCOS(TM) Laser System for Research Applications Including Stem Cell Research, Gene …

Posted: March 20, 2012 at 1:27 pm

XYRCOS Provides Advanced Research Capabilities in a Sleek New Design With Improved Fluorescence, Optics and RED-i Target Locator Built Directly Inside Microscope Objective

BEVERLY, MA and TORONTO--(Marketwire - Mar 20, 2012) - Hamilton Thorne Ltd. (TSX VENTURE: HTL), a leading provider of precision laser devices and advanced imaging systems for the fertility, stem cell and developmental biology research markets, today announced the launch of its leading-edge XYRCOS laser system for advanced research applications. The XYRCOS laser offers a significant advance in integrated laser optics, providing additional functionality, increased resolution and compatibility with all major microscope models.

The elegant and sleek new design of the XYRCOS is engineered to have the laser and RED-i target locator built directly inside the objective, providing unparalleled precision while saving researchers from tedious alignment procedures. The improved working distance of the XYRCOS laser objective provides researchers with more compatibility and flexibility to integrate with existing laboratory equipment. The laser also features enhanced UV transmission/fluorescence, which is compatible with many fluorescing stains used in advanced research applications. The XYRCOS offers additional benefits for cutting-edge embryo micromanipulation applications such as the creation of transgenic animals, gene targeting, and stem cell research including blastocyst injection, 8-cell injection, and laser-assisted animal model IVF.

"Built on the same hardware platform as our popular turret-mounted lasers, the new XYRCOS offers researchers an elegant laser design that enables intricate and delicate cell micromanipulation capabilities. Already installed at some of our industry-leading beta site customers, the XYRCOS laser has been used in some of today's most advanced and celebrated scientific research," said David Wolf, President, Chief Executive Officer of Hamilton Thorne Ltd. "The improved image quality, better working distance and enhanced fluorescence provides researchers with significant advantages in working with advanced applications such as stem cell research and developmental biology, and has already proven effective in important research studies such as reprogramming cells."

"With its compact design, long working distance and excellent optics, the new XYRCOS laser provides a flexible research tool that can be used with any lab microscope and fits easily into the current daily workflow," said Diarmaid Douglas-Hamilton, Chief Technology Officer, Senior Vice President of Research & Development and Co-founder of Hamilton Thorne. "The improved fluorescence has been especially useful in the lab since the XYRCOS installs directly onto the turret, leaving both the fluorescence and filter cube ports free for normal use, providing significant advantages in how cells can be viewed and analyzed."

The XYRCOS laser system will be available in both 40X and 20X objectives, and will also have the popular Staccato multi-pulse laser activation software as an additional feature option. Due to its smaller footprint, the XYRCOS allows full use of the turret and fits into all major microscopes, including newer and upright microscopes. The XYRCOS is available for non-clinical research use only.

About Hamilton Thorne Ltd. (www.hamiltonthorne.com)

Hamilton Thorne designs, manufactures and distributes precision laser devices and advanced imaging systems for the fertility, stem cell and development biology research markets. It provides novel solutions for Life Science that reduce cost, increase productivity, improve results and enable research breakthroughs in regenerative medicine, stem cell research and fertility markets. Hamilton Thorne's laser products attach to standard inverted microscopes and operate as robotic micro-surgeons, enabling a wide array of scientific applications and IVF procedures. Its imaging systems improve outcomes in human IVF clinics and animal breeding facilities and provide high-end toxicology analyses.

Hamilton Thorne's growing customer base includes pharmaceutical companies, biotechnology companies, fertility clinics, university research centers, and other commercial and academic research establishments worldwide. Current customers include world-leading research labs such as Harvard, MIT, Yale, McGill, DuPont, Monsanto, Charles River Labs, Jackson Labs, Merck, Novartis, Pfizer, and Oxford and Cambridge.

Neither the Toronto Venture Exchange, nor its regulation services provider (as that term is defined in the policies of the exchange), accepts responsibility for the adequacy or accuracy of this release.

The rest is here:
Hamilton Thorne Launches XYRCOS(TM) Laser System for Research Applications Including Stem Cell Research, Gene ...

Posted in Stem Cell Research | Comments Off on Hamilton Thorne Launches XYRCOS(TM) Laser System for Research Applications Including Stem Cell Research, Gene …

International Stem Cell Corporation Announces 2011 Financial Results

Posted: March 20, 2012 at 1:26 pm

CARLSBAD, Calif.--(BUSINESS WIRE)--

International Stem Cell Corporation (OTCBB: ISCO.OB - News) (www.internationalstemcell.com) today announced year-end financial results for the year ended December 31, 2011. ISCO is a California-based development-stage biotechnology company that is focused on therapeutic, biomedical and cosmeceutical product development and commercialization with multiple long-term therapeutic opportunities and two revenue-generating businesses offering potential for increased future revenue.

ISCO reported revenue of $1.1 million for the fourth quarter ended December 31, 2011, reflecting a 110% increase from the same period of the prior year. For the twelve months ended December 31, 2011, the Company reported revenue of $4.5 million, reflecting a year-over-year increase of 189%. The increases in revenues in both periods were primarily driven by strong sales at ISCOs wholly-owned subsidiary Lifeline Skin Care (LSC). In addition, steady growth in sales from ISCOs other wholly-owned subsidiary, Lifeline Cell Technology (LCT), contributed to the increases in revenues for both periods.

While the Company continued to invest in therapeutic projects, development of new technologies, and expansion of products and channels of distribution, to date we have generated limited revenue to support our core therapeutic research and development efforts. For the three months ended December 31, 2011, development expenses, excluding cost of sales, increased $507,000 or 17% compared with the same period of 2010, a reflection of increased G&A expenses resulting from higher stock-based compensation expenses.

For the twelve months ended December 31, 2011, development expenses, excluding costs of sales, increased approximately $3.0 million or 26% when compared with the prior year period.The majority of the increase was primarily due to increases in general and administrative and research and development activities. General and administrative expenses increased largely due to increased non-cash stock-based compensation, higher headcount, and increased expenses related business development activity and general corporate expenses. Research & Development expenses increased mainly due to increased number and complexity of experiments associated with our scientific projects. The increase in development expenses was also related to increased research activities on therapeutic products and product research activities for LSC and LCT coupled with increased sales and marketing expenses related to our skin care products.

Some of the 2011 Highlights:

-- A number of donors willing to provide oocytes for research purposed were enrolled in ISCO's program to establish a bank of clinical grade hpSC capable of being immune-matched to millions of patients.

-- The Research and Development team successfully completed the first series of preclinical studies that supports the therapeutic use of hepatocytes (liver cells) and neuronal cells derived from human parthenogenetic stem cells (hpSC). These in vivo experiments demonstrated that the derived cells are able to survive in targeted locations in mice without causing tumors.

-- We became Sarbanes-Oxley compliant and maintained, in all material respects, effective internal controls over financial reporting as of December 31, 2011.

-- We strengthened our Management Team through the appointments of well-known industry executives: Kurt May as President & Chief Operating Officer, Linh Nguyen as Chief Financial Officer, Donna Queen as Vice President of Marketing and Business Development for LSC.

See the original post here:
International Stem Cell Corporation Announces 2011 Financial Results

Posted in Stem Cell Research | Comments Off on International Stem Cell Corporation Announces 2011 Financial Results

9/11 search and rescue dog receives stem cell therapy

Posted: March 20, 2012 at 1:16 pm

A special dog used to help people is getting some much-needed help of her own at a Virginia clinic, myFOXdc.com reported.

Red, a 12-year-old black Labrador, is one of the last surviving search and rescue dogs deployed during the 9/11 attacks.

Her handler, Heather Roche, told WTTG-TV that Red was recently certified when Sept. 11, 2001, occurred, and the devastating terror attacks were her first big mission.

Red's job was to find DNA evidence at The Pentagon's north parking lot with 26 other dogs, and according to Roche, she did a "fantastic job."

"I got her as a puppy ... You have to convince [her] everything that she does, whether it's climbing ladders or any kind of search, that it's her idea," Roche told WTTG-TV. "No matter what I've asked her to do, she's done it and she's done it flawlessly."

But in her old age Red developed crippling arthritis, and underwent stem cell regenerative therapy Monday to help ease her pain so she can get back out on the job.

Dr. John Herrity of Burke Animal Clinic in Burke, Va., told WTTG-TV, "Red has a back issue that, after a fall from a ladder has not really been right, and has been living in pain, so we're going to give those stem cells IV [intravenously] and then also inject them along the back to try to help Red's comfort."

"She's had a great career and has made a difference to a lot of families by bringing their loved ones home," Roche said.

Click here to read more.

Read the rest here:
9/11 search and rescue dog receives stem cell therapy

Posted in Stem Cell Therapy | Comments Off on 9/11 search and rescue dog receives stem cell therapy

SanBio Announces Enrollment of First Cohort of Patients in Its Clinical Trial of Stem Cell Therapy for Chronic Stroke

Posted: March 20, 2012 at 1:16 pm

MOUNTAIN VIEW, Calif., March 20, 2012 /PRNewswire/ -- SanBio Inc. today announced the successful enrollment of the first dose cohort of patients in its Phase 1/2a clinical trial testing the safety and efficacy of a novel allogeneic stem cell therapy product, SB623, in patients suffering from chronic deficits resulting from previous stroke injuries. The first 6 patients, of a total of 18, have been successfully administered SB623. The trial is being conducted at Stanford University and the University of Pittsburgh. No safety concerns have been reported. For details regarding this clinical trial, please refer to http://www.strokeclinicaltrial.org.

SB623 is derived from adult bone marrow and has shown safety and efficacy in rodent models of chronic stroke. "This represents a major milestone in the human clinical testing of this important new approach for regenerative medicine", said Keita Mori, SanBio CEO. "We are pleased to learn that the initial dose level was well tolerated."

SB623 is being delivered to the damaged region of the brains of patients who have suffered an ischemic stroke. Product safety is the primary focus of the study but various measurements of efficacy are also being tested.

"The successful completion of the initial dose cohort is a major step in any first-in-human study", said Dr. Ernest Yankee, SanBio's Vice President of Development. "We are looking forward to initiating the next two dose cohorts and wrapping up the study. The safety findings thus far are very encouraging"

About SB623: SB623 is a proprietary cell therapy product consisting of cells derived from genetically engineered bone marrow stromal cells obtained from healthy adult donors. SB623 is administered adjacent to the area damaged by stroke and functions by producing proteins that aid the regenerative process.

About SanBio: SanBio is a privately held San Francisco Bay Area biotechnology company focused on the discovery and development of new regenerative cell therapy products.

For more information: http://www.san-bio.com

Go here to read the rest:
SanBio Announces Enrollment of First Cohort of Patients in Its Clinical Trial of Stem Cell Therapy for Chronic Stroke

Posted in Stem Cell Therapy | Comments Off on SanBio Announces Enrollment of First Cohort of Patients in Its Clinical Trial of Stem Cell Therapy for Chronic Stroke

Page 2,803«..1020..2,8022,8032,8042,805..2,8102,820..»