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Media, Sera and Reagents in Biotechnology market 2022-2028 Increase in Demand, biggest innovation and Expected to Boost Growth ManufactureLink -…

Posted: June 4, 2022 at 2:07 am

The Global Media, Sera and Reagents in Biotechnology Market research report provides systematic information and powerful insights into the potential size, market share, industrys growth prospects, scope, and challenges. The report evaluates the CAGR, value, volume, sales, revenue, and dynamics of the market during the forecast period of 2022-2028. This report focuses on Media, Sera and Reagents in Biotechnology market growth, current market trends, key driving factors, and overall market prospects. The industry report includes the sales figures, market growth rate, production, capacity, and gross profit margin of each player based on the regional and global market position.

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The market overview included in this report provides information from a wide range of resources like government organizations, established companies, trade and industry associations, industry brokers and other such regulatory and non-regulatory bodies. The data acquired from these organizations authenticate the Media, Sera and Reagents in Biotechnology research report, thereby aiding the clients in better decision making. Additionally, the data provided in this report offers a contemporary understanding of the market dynamics.

Media, Sera and Reagents in Biotechnology Market 2022-2028 Research Report is a professional and in-depth study on the current state of the Media, Sera and Reagents in Biotechnology industry. It provides key analysis on the market status of the Media, Sera and Reagents in Biotechnology manufacturers with best facts and figures, meaning, definition, SWOT analysis, expert opinions and the latest developments across the globe. The Report also calculate the market size, Media, Sera and Reagents in Biotechnology Sales, Price, Revenue, Gross Margin and Market Share, cost structure and growth rate. The report considers the revenue generated from the sales of This Report and technologies by various application segments and Browse Market data Tables and Figures.

The leading players are focusing mainly on technological advancements in order to improve efficiency. The long-term development patterns for this market can be captured by continuing the ongoing process improvements and financial stability to invest in the best strategies.

Top Key players of Media, Sera and Reagents in Biotechnology Market are:Athena Environmental Science, Inc.BectonDickinsonCellGenixGE HealthcareLonzaThermo Fisher Scientific, Inc.

Global Media, Sera and Reagents in Biotechnology Market Scope and Size:The Media, Sera and Reagents in Biotechnology market is declared segment by company, region (country), type, and application. Players, stakeholders, and other participants in the global Media, Sera and Reagents in Biotechnology market will gain the market scope as they use the report as a powerful resource. The segmental analysis focuses on revenue and product by type and application and the forecast period of 2022-2028.

Media, Sera and Reagents in Biotechnology Market Types covered in this report are:MediaSeraReagents

Market Applications covered in this report are:Cancer ResearchVirologyToxicity TestingVaccine ProductionDrug Development

Regional AnalysisNorth America (the United States, Canada, and Mexico)Europe (Germany, France, UK, Russia, and Italy)Asia-Pacific (China, Japan, Korea, India, and Southeast Asia)South America (Brazil, Argentina, Colombia, etc.)The Middle East and Africa (Saudi Arabia, UAE, Egypt, Nigeria, and South Africa)

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The Media, Sera and Reagents in Biotechnology market report provides a detailed analysis of global market size, regional and country-level market size, segmentation market growth, market share, competitive Landscape, sales analysis, impact of domestic and global market players, value chain optimization, trade regulations, recent developments, opportunities analysis, strategic market growth analysis, product launches, area marketplace expanding, and technological innovations.

The content of the study subjects includes a total of 15 chapters:

Chapter 1, to describe Media, Sera and Reagents in Biotechnology product scope, market overview, market opportunities, market driving force and market risks. Chapter 2, to profile the top manufacturers of Media, Sera and Reagents in Biotechnology, with price, sales, revenue and global market share of Media, Sera and Reagents in Biotechnology in 2020 and 2021. Chapter 3, the Media, Sera and Reagents in Biotechnology competitive situation, sales, revenue and global market share of top manufacturers are analyzed emphatically by landscape contrast. Chapter 4, the Media, Sera and Reagents in Biotechnology breakdown data are shown at the regional level, to show the sales, revenue and growth by regions, from 2016 to 2021. Chapter 5, 6, 7, 8 and 9, to break the sales data at the country level, with sales, revenue and market share for key countries in the world, from 2016 to 2021. Chapter 10 and 11, to segment the sales by type and application, with sales market share and growth rate by type, application, from 2016 to 2021. Chapter 12, Media, Sera and Reagents in Biotechnology market forecast, by regions, type and application, with sales and revenue, from 2022 to 2028. Chapter 13, 14 and 15, to describe Media, Sera and Reagents in Biotechnology sales channel, distributors, customers, research findings and conclusion, appendix and data source.

Key Point of the Media, Sera and Reagents in Biotechnology Market report:

Geographical distribution, company profiling, and various other market segmentation are provided in the report. For better understanding of the global Media, Sera and Reagents in Biotechnology market status, the accurate market valuation which comprises of size, share, and revenue are also covered. Analysis of the competitive dynamic factors better extrapolate the complete market overview What will be the size of the emerging Media, Sera and Reagents in Biotechnology market in 2028? The latest trends, opportunities and challenges, and growth drivers provide better construal of the Media, Sera and Reagents in Biotechnology Market. In-detail industrial analysis, sales study, and production understanding shed more light on the future market growth rate and scope. Report also offers the opportunity for customization as per the customer request.

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At last, the Media, Sera and Reagents in Biotechnology Market report includes investment come analysis and development trend analysis. The present and future opportunities of the fastest growing international industry segments are coated throughout this report. This report additionally presents product specification, manufacturing method, and product cost structure, and price structure.

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Media, Sera and Reagents in Biotechnology market 2022-2028 Increase in Demand, biggest innovation and Expected to Boost Growth ManufactureLink -...

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Biosimulation Market Size, Scope and Forecast | Insilico Biotechnology, INOSIM Software, Evidera, Chemical Computing Group, Certara, Simulations Plus,…

Posted: June 4, 2022 at 2:07 am

New Jersey, United States TheBiosimulation Marketreport is the result of extensive and expert research into theBiosimulationindustry. TheBiosimulationMarketreport explains what the market is all about, the market prognosis, several segmentations, and everything that falls under the markets umbrella. It also looks at major and secondary market drivers, market share, potential sales volume, regional analysis, and the markets key segments. The research also includes key variables that contribute to the markets growth as well as elements that might stifle the markets growth. The professionals at VM Reports applied precise research techniques and other analyses.

PESTLE analysis and SWOT analysis are two of the analyses utilized in theBiosimulationMarketresearch, and they shed light on numerous internal and external variables that affect the market in every situation. It also includes a section that identifies strengths, weaknesses, opportunities, and threats, as well as Porters five forces model.

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There is also a section dedicated to significant actors and their plans, such as acquisitions, collaborations, and so on. The material in the Biosimulation Market research was gathered mostly via expert opinions, interviews, and surveys. Verified Market Research experts have created a Biosimulation Market research that is full of clarity, accuracy, and useful information. The data in the report is quite accurate and reliable, with no duplicates or mistakes.

Key Players Mentioned in the Biosimulation Market Research Report:

Insilico Biotechnology, INOSIM Software, Evidera, Chemical Computing Group, Certara, Simulations Plus, ACD/Labs, Dassault Systmes, Nuventra Pharma, Genedata. Company.

BiosimulationMarket Segmentation:

Bio Simulation Market, By Product

Software Services

Bio Simulation Market, By Application

Drug Development Drug Discovery Others

Bio Simulation Market, By End-User

Pharmaceutical and Biotechnology Companies Research Institutes Contract Research Organizations Regulatory Authorities Other

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Biosimulation Market Report Scope

Key questions answered in the report:

1. Which are the five top players of the Biosimulation market?

2. How will the Biosimulation market change in the next five years?

3. Which product and application will take a lions share of the Biosimulation market?

4. What are the drivers and restraints of the Biosimulation market?

5. Which regional market will show the highest growth?

6. What will be the CAGR and size of the Biosimulation market throughout the forecast period?

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VMI provides a holistic overview and global competitive landscape with respect to Region, Country, and Segment, and Key players of your market. Present your Market Report & findings with an inbuilt presentation feature saving over 70% of your time and resources for Investor, Sales & Marketing, R&D, and Product Development pitches. VMI enables data delivery In Excel and Interactive PDF formats with over 15+ Key Market Indicators for your market.

Visualize Biosimulation Market using VMI @ https://www.verifiedmarketresearch.com/vmintelligence/

About Us: Verified Market Research

Verified Market Research is a leading Global Research and Consulting firm that has been providing advanced analytical research solutions, custom consulting and in-depth data analysis for 10+ years to individuals and companies alike that are looking for accurate, reliable and up to date research data and technical consulting. We offer insights into strategic and growth analyses, Data necessary to achieve corporate goals and help make critical revenue decisions.

Our research studies help our clients make superior data-driven decisions, understand market forecast, capitalize on future opportunities and optimize efficiency by working as their partner to deliver accurate and valuable information. The industries we cover span over a large spectrum including Technology, Chemicals, Manufacturing, Energy, Food and Beverages, Automotive, Robotics, Packaging, Construction, Mining & Gas. Etc.

We, at Verified Market Research, assist in understanding holistic market indicating factors and most current and future market trends. Our analysts, with their high expertise in data gathering and governance, utilize industry techniques to collate and examine data at all stages. They are trained to combine modern data collection techniques, superior research methodology, subject expertise and years of collective experience to produce informative and accurate research.

Having serviced over 5000+ clients, we have provided reliable market research services to more than 100 Global Fortune 500 companies such as Amazon, Dell, IBM, Shell, Exxon Mobil, General Electric, Siemens, Microsoft, Sony and Hitachi. We have co-consulted with some of the worlds leading consulting firms like McKinsey & Company, Boston Consulting Group, Bain and Company for custom research and consulting projects for businesses worldwide.

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Verified Market Research

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Biosimulation Market Size, Scope and Forecast | Insilico Biotechnology, INOSIM Software, Evidera, Chemical Computing Group, Certara, Simulations Plus,...

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Canthaxanthin Market Size, Scope and Forecast | Novepha Company, Guangzhou Wisdom Biotechnology, DSM, BASF, Novus International, Zipont Chem Tech,…

Posted: June 4, 2022 at 2:07 am

New Jersey, United States TheCanthaxanthin Marketreport is the result of extensive and expert research into theCanthaxanthinindustry. TheCanthaxanthinMarketreport explains what the market is all about, the market prognosis, several segmentations, and everything that falls under the markets umbrella. It also looks at major and secondary market drivers, market share, potential sales volume, regional analysis, and the markets key segments. The research also includes key variables that contribute to the markets growth as well as elements that might stifle the markets growth. The professionals at VM Reports applied precise research techniques and other analyses.

PESTLE analysis and SWOT analysis are two of the analyses utilized in theCanthaxanthinMarketresearch, and they shed light on numerous internal and external variables that affect the market in every situation. It also includes a section that identifies strengths, weaknesses, opportunities, and threats, as well as Porters five forces model.

Get Full PDF Sample Copy of Report: (Including Full TOC, List of Tables & Figures, Chart) @https://www.verifiedmarketresearch.com/download-sample/?rid=38503

There is also a section dedicated to significant actors and their plans, such as acquisitions, collaborations, and so on. The material in the Canthaxanthin Market research was gathered mostly via expert opinions, interviews, and surveys. Verified Market Research experts have created a Canthaxanthin Market research that is full of clarity, accuracy, and useful information. The data in the report is quite accurate and reliable, with no duplicates or mistakes.

Key Players Mentioned in the Canthaxanthin Market Research Report:

Novepha Company, Guangzhou Wisdom Biotechnology, DSM, BASF, Novus International, Zipont Chem Tech, Wellgreen Technology Company Limited, Parchem.

CanthaxanthinMarket Segmentation:

Canthaxanthin Market, By Source

Natural Synthetic

Canthaxanthin Market, By Application

Food Additive Feed Additive Cosmetics and Personal Care

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Canthaxanthin Market Report Scope

Key questions answered in the report:

1. Which are the five top players of the Canthaxanthin market?

2. How will the Canthaxanthin market change in the next five years?

3. Which product and application will take a lions share of the Canthaxanthin market?

4. What are the drivers and restraints of the Canthaxanthin market?

5. Which regional market will show the highest growth?

6. What will be the CAGR and size of the Canthaxanthin market throughout the forecast period?

For More Information or Query or Customization Before Buying, Visit @ https://www.verifiedmarketresearch.com/product/canthaxanthin-market/

Visualize Canthaxanthin Market using Verified Market Intelligence:-

Verified Market Intelligence is our BI-enabled platform for narrative storytelling of this market. VMI offers in-depth forecasted trends and accurate Insights on over 20,000+ emerging & niche markets, helping you make critical revenue-impacting decisions for a brilliant future.

VMI provides a holistic overview and global competitive landscape with respect to Region, Country, and Segment, and Key players of your market. Present your Market Report & findings with an inbuilt presentation feature saving over 70% of your time and resources for Investor, Sales & Marketing, R&D, and Product Development pitches. VMI enables data delivery In Excel and Interactive PDF formats with over 15+ Key Market Indicators for your market.

Visualize Canthaxanthin Market using VMI @ https://www.verifiedmarketresearch.com/vmintelligence/

About Us: Verified Market Research

Verified Market Research is a leading Global Research and Consulting firm that has been providing advanced analytical research solutions, custom consulting and in-depth data analysis for 10+ years to individuals and companies alike that are looking for accurate, reliable and up to date research data and technical consulting. We offer insights into strategic and growth analyses, Data necessary to achieve corporate goals and help make critical revenue decisions.

Our research studies help our clients make superior data-driven decisions, understand market forecast, capitalize on future opportunities and optimize efficiency by working as their partner to deliver accurate and valuable information. The industries we cover span over a large spectrum including Technology, Chemicals, Manufacturing, Energy, Food and Beverages, Automotive, Robotics, Packaging, Construction, Mining & Gas. Etc.

We, at Verified Market Research, assist in understanding holistic market indicating factors and most current and future market trends. Our analysts, with their high expertise in data gathering and governance, utilize industry techniques to collate and examine data at all stages. They are trained to combine modern data collection techniques, superior research methodology, subject expertise and years of collective experience to produce informative and accurate research.

Having serviced over 5000+ clients, we have provided reliable market research services to more than 100 Global Fortune 500 companies such as Amazon, Dell, IBM, Shell, Exxon Mobil, General Electric, Siemens, Microsoft, Sony and Hitachi. We have co-consulted with some of the worlds leading consulting firms like McKinsey & Company, Boston Consulting Group, Bain and Company for custom research and consulting projects for businesses worldwide.

Contact us:

Mr. Edwyne Fernandes

Verified Market Research

US: +1 (650)-781-4080UK: +44 (753)-715-0008APAC: +61 (488)-85-9400US Toll-Free: +1 (800)-782-1768

Email: sales@verifiedmarketresearch.com

Website:- https://www.verifiedmarketresearch.com/

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Canthaxanthin Market Size, Scope and Forecast | Novepha Company, Guangzhou Wisdom Biotechnology, DSM, BASF, Novus International, Zipont Chem Tech,...

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Simpson Healthcare AWARDED ISO/IEC 27001:2013 & ISO/IEC 27701:2019 CERTIFICATION – PR Newswire

Posted: June 4, 2022 at 2:07 am

OLD LYME, Conn., June 2, 2022 /PRNewswire/ -- Simpson Healthcare, a leading scientific agency providing the pharmaceutical, biotechnology, medical diagnostic and device industries with a wide range of services in support of overall marketing strategies, announced today that it has successfully completed the ISO/IEC 27001 certification and its privacy information management extension ISO/IEC 27701.

Scott Algiere, Chief Executive Officer of Simpson Healthcare, commented, "ISO 27001 and ISO 27701 are globally renowned and trusted industry standards. This is an achievement for Simpson Healthcare and demonstrates our continued commitment to ensure security and privacy". This provides independent, third-party validation that we have the appropriate controls in place to mitigate risks related to the services we provide to our customers and is key to our customers upholding their own regulatory obligations. Abdullah Amin, SVP Engineering + IT Security, commented, "These certifications highlight our commitment to data privacy and information security. Our customers know that their information is secure and processed appropriately by maintaining security and compliance".

About ISO/IEC 27001

For ISO/IEC 27001 certification, the scope of Simpson Healthcare information security management system (ISMS) includes people, processes, and technology for creating and supporting their products and services. The report provides assurance to customers that Simpson Healthcare adheres to these stringent, internationally recognized security standards.

ISO/IEC 27001:2013 is one of the most widely recognized and internationally accepted information security standards, detailing best practices for the management of information security and privacy. It identifies requirements for a comprehensive Information Security Management System (ISMS) and establishes quality standards used to measure an organization's IT security controls and processes for handling and managing data.

About ISO/IEC 27701

For ISO/IEC 27701 certification, the scope of Simpson Healthcare privacy information management system (PIMS) includes alignment and incorporation of privacy best practices into people, processes, and technology for protection and management of personally identifiable information (PII).

ISO/IEC 27701:2019 is built to complement the widely-used ISO/IEC 27001 standard for information security management. It specifies requirements and provides guidance for a Privacy Information Management System (PIMS). ISO/IEC 27701 accomplishes the security and privacy integration through a framework for managing personal data that can be used by both data controllers and data processors, a key distinction for General Data Protection Regulation (GDPR) compliance.

A-LIGN, an independent and accredited third-party CPA firm, completed the assessment of Simpson Healthcare' systems and successfully validated that its controls meet the standards required for ISO/IEC 27001 certification as well as ISO/IEC 27701 extension.

About Simpson Healthcare

Simpson Healthcare is an established scientific agency that provides the pharmaceutical, biotechnology, medical diagnostic and device industries with a wide range of services in support of overall marketing strategies. The products and services provided enhance a company's value for the benefit of the stakeholders, while simultaneously disseminating new biomedical knowledge for the benefit of healthcare providers and their patients.

Simpson's high-quality, creative, strategic solutions are delivered with unparalleled customer service, and include brand strategy, KOL development, advisory boards, speaker bureaus, live/virtual speaker training, content development, interactive patient case videos, sales force training, and community live events.

Contact: Abdullah Amin, SVP Engineering + IT Security [emailprotected]

SOURCE Simpson Healthcare

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Simpson Healthcare AWARDED ISO/IEC 27001:2013 & ISO/IEC 27701:2019 CERTIFICATION - PR Newswire

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Maine health care workers to appeal order to disclose their names in vaccine mandate lawsuit – Lewiston Sun Journal

Posted: June 4, 2022 at 2:04 am

Nine plaintiffs who anonymously sued Gov. Janet Mills over a COVID-19 mandate for health care workers will appeal a U.S. District Court judges decision requiring them to disclose their names by June 7.

The group filed its complaint in federal court last August, before the vaccine mandate for employees of designated Maine health care facilities went into effect Oct. 29.

Using pseudonyms, the health care workers argued that it was their religious right to refuse the vaccine overtheir belief that fetal stem cells from abortions were used to develop it. The state mandate does not allow for religious exemptions.

The Portland Press Herald, Kennebec Journal, Morning Sentinel and Sun Journal filed a motion in November challenging the groups right to file the complaint anonymously.

In his 13-page ruling Tuesday, Chief U.S. District Court Judge Jon D. Levy said he at first allowed the group to withhold their names because they argued they were afraid of the public passions concerning mandatory COVID-19 vaccinations, and that they were at a heightened risk of severe social stigma and worse if their identities were revealed.

In the final analysis, however, there is a near total absence of proof that their expressed fears are objectively reasonable, Levy wrote Tuesday. The Plaintiffs privacy interests have not been shown to outweigh the public interest associated with the presumption of openness that applies to civil proceedings.

Attorneys for the unnamed health care workers did not respond to requests Wednesday afternoon to discuss their appeal. They are represented by Maine attorney Steve Whiting, and lawyers from Liberty Counsel, a conservative, religious law firm based in Florida that has participated in several lawsuits against Maine and other states over COVID-19 vaccine mandates and restrictions. Nationally, the firm also has opposed safe and legal access to abortions and same-sex marriage, and the Southern Poverty Law Center has identified the firm as a hate group.

Before filing the notice to appeal, a spokesperson for Liberty Counsel told the Portland Press Herald on Tuesday night that the firm would not speak with reporters about Levys ruling because of the papers involvement in the lawsuit.

In an emailed statement Wednesday, attorney Sigmund Schutz, who represents the newspapers, said he plans to vigorously defend Levys order.

Chief Judge Levys decision vindicates the bedrock principle of the American justice system that courts operate in secret only in exceptional circumstances, Schutz wrote.

Shannon Jankowski, staff attorney for the Reporters Committee for Freedom of the Press, has joined Schutz as co-counsel. Jankowski said Wednesday that this is the only case the committee is involved in related to vaccine mandates, but that there are several court cases around the country in which people using pseudonyms have tried to challenge mandates. Jankowski said hundreds of other people around the country have filed complaints concerning vaccine mandates in their own names.

In Arizona in January, a judge denied a federal employees motion to anonymously sue President Biden over the U.S. governments vaccine mandate. At about the same time in Colorado, a judge agreed to let a group of university employees anonymously challenge their employers mandate.

These plaintiffs are attempting to invalidate a vaccine mandate that applies throughout the state of Maine, Jankowski said of the anonymous plaintiffs in the Maine lawsuit. This is something that has broad-ranging impacts on all citizens of Maine, and the public has the right to know who these plaintiffs are, what role they play in the health care system. Its important information for the public to be able to assess for themselves whats going on in this case.

Levy is still considering the lawsuit against the vaccine mandate. Meanwhile, federal judges have refused to block the mandate, which has been in effect since last Oct. 29. The states major health care providers reported at the time that most workers chose to get the shots and keep their jobs.

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Maine health care workers to appeal order to disclose their names in vaccine mandate lawsuit - Lewiston Sun Journal

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No, "Top Gun" isn’t an anti-woke success story, but rather a tribute to aging Tom Cruise and balls – Salon

Posted: June 4, 2022 at 2:04 am

Explaining the success of "Top Gun: Maverick" isn't tough. All that's required is having some inkling of what we the people enjoy. We adore watching Tom Cruise in action flicks, for one thing, proven by his long track record of bankability.

Fast vehicles are high on our list of likes, too. Put Tom Cruise's Navy Captain Pete "Maverick" Mitchell inside a fighter jet, show him exercising his need for speed through challenging terrain, and guess what? People will plunk down money to see that on as large of a screen as possible.

But do you know what Americans really love? Balls. That affair transcends political affiliation and tribalism. The angry red balls in need of scientifically proven medication tend to get the most attention, but let's not count out our frustrated blue balls and the tricky, harder-to-pin-down purple ones. They're out there too, ready to bounce off their couches and into theaters.

Everyone's feeling a little deflated these days, and Cruise and "Top Gun: Maverick" director Joseph Kosinski know this. Who can forget the 1986 originalwhen a 25-year-old Cruise and his co-star Val Kilmer, each in their oiled-up prime, took to the beach to flex and play . . . what was it? Volleyball? Honestly, I wasn't paying much attention to the sport part.

RELATED: The lost meaning of "Top Gun"

This time around there's a female ace pilot in the mix, Lt. Natasha "Phoenix" Trace (Monica Barbaro), and the game is touch football. Cruise's Maverick, their instructor, envisions the game as having a purpose beyond posturing. It's about team building, he explains to his short-tempered boss Vice Admiral Beau "Cyclone" Simpson (Jon Hamm).

Sure enough, the younger guns all learn to pass the ball, defend the ball, and have fun with the ball.

But the audience knows the teamwork exercise isn't the reason the "Top Gun" sequel includes this scene. Its secondary purpose, the one that rings truer, is to remind us yet again that 59-year-old Cruise is still as ripped as his decades-younger co-stars.

Those who can, do. As for those who can't, forget it. Maverick isn't the type.

That takes stones along with, I'm guessing, many hours of physical effort guided by the best personal trainers in the world, a strict diet, and a supplement regimen that may or may not include alien stem cells. Any mortal may follow that plan and still lack the fortitude to show their vintage pecs to the sun.

Not Tom Cruise. Maverick's got it like that. Those who can, do. As for those who can't, forget it. Maverick isn't the type. The younger pilots may be elite, but it's understood that the chiseled veteran is going to run the ball into the end zone.

No wonder the right-wing is lurching to claim the box office record-breaking success of "Top Gun: Maverick" as a tribute, they say, to "anti-wokeness." Several Fox News hosts crowed about this in the days following the movie's release, echoing Breitbart column headlines. Meghan McCain was the last to jump on the wagon with her Wednesday column in that All-American news rag, The Daily Mail. "Hollywood must wake up to the reality that 'go woke, go broke' is real," she wrote.

The Arizona sage went on to praise "Top Gun: Maverick" for having all the qualities of the typical summertime blockbuster. "The movie isn't overly political, it isn't depressing, it isn't focusing on the flaws of the United States of America and why we suck and why our flag and national anthem aren't worth honoring."

Well, duh. Cruise isn't remaking "Born on the Fourth of July." Clearly this movie is not that one.

Besides, none of the three highest-grossing movies of 2022 "Doctor Strange in the Multiverse of Madness," "The Batman" and "Spider-Man: No Way Home" gripes about America's flaws or disrespects the flag. Why on Earth would they?

However, "Top Gun: Maverick" does something those films don't, in that it comforts a demographic that may harbor grave concerns about its impending obsolescence, its waning influence, and declining potency.

In short, this movie validates the viability of old balls of every size and sort, from raisins to apricots.

Paramount's own demographics breakdown backs this up. It indicates that 55% of the opening weekend's audience was over the age of 35. We're talking elder Millennials, Generation Xers, and Boomers many of whom watched the original "Top Gun" back in the '80s and may be feeling the 36 years that have transpired since.

Tom Cruise plays Capt. Pete "Maverick" Mitchell in "Top Gun: Maverick" (Paramount Pictures / Skydance / Jerry Bruckheimer Films)"Top Gun: Maverick" was made for that crowd even as it bridges generational gaps by emphasizing spectacle over any message, and certainly none deeper than, "Look at Tom Cruise, still keepin' it tight."

For emotional flavor it tosses in some father-son healing between Maverick's father figure and his surrogate child Lt. Bradley "Rooster" Bradshaw (Miles Teller), the son of his dead best friend Goose, by way of a "Behind Enemy Lines" fly-by.

But the main hooks are theroaring flight sequences that vibrate the theater's walls, with visuals reminiscent of Death Star's trench in "Star Wars Episode IV: A New Hope," only brought to life by scenes filmed in F/A-18s flown by top pilots.

"Top Gun: Maverick" is a two-hour, 11-minute Cialis ad.

Long before all of that kicks in, though, we see Maverick being cut down to size by Ed Harris' leathery Rear Admiral Chester "Hammer" Cain, who is keen to replace the likes of our hero with drone technology. "The future is coming, and you're not in it," he growls before adding, "The end is inevitable, Maverick. Your kind is headed for extinction!"

Once you understand that part of the equation, you may get why conservatives are desperate to claim this as their movie.

To that portion of the audience, "Top Gun: Maverick" is a two-hour, 11-minute Cialis ad, starring a guy with flexible hips who can still climb a ladder to clean his own roof gutters.

Maverick represents that aging audience's ideal self. He blasts down the road on his All-American Kawasaki motorcycle, refusing to wear a helmet or play by the rules. His motto is, "Don't think, just do." His three-and-a-half decades-long friendship with Iceman, now known as four-star Admiral Tom "Iceman" Kazansky, ensures he'll never suffer any consequences for, say, disobeying orders and destroying a prototype aircraft that's probably worth the equivalent GDP of a small nation.

He teaches the next generation of the world's best fighter pilots to fly a mission that he ends up leading anyway. Because the world needs Maverick. He's that exceptional.

Is this evidence of intentional "anti-wokeness"? Not so fast. Consider that the sequel also introduces the local bar as a gathering place for men and women in uniform that's run by Maverick's love interest Penny Benjamin (Jennifer Connelly), the "Admiral's daughter" Maverick got in trouble with way back when.

Jennifer Connelly plays Penny Benjamin and Tom Cruise plays Capt. Pete "Maverick" Mitchell in "Top Gun: Maverick" (Paramount Pictures / Skydance / Jerry Bruckheimer Films)In the 1986 flick, the first female presence is introduced by an anonymous actor's thigh poking out from under her skirt. In 2022, a woman makes the bar's rules and has the ovaries to get Maverick physically tossed from the place.

"Top Gun: Maverick" evolves with the times in other ways, too. Maverick's inclusive squad includes Barbaro's Phoenix and her Weapon Systems Officer Lt. Robert "Bob" Floyd (Lewis Pullman), the least aggro male in the class, along with Jay Ellis' Lt. Reuben "Payback" Fitch and Danny Ramirez's Lt. Mickey "Fanboy" Garcia.

The candidate class also includes other non-white faces, a step up from the 1986 class, which includes two Black men, only one of whom had any lines . . . and was passed over for the final mission so Maverick could fly with a WSO from his old squad.

This doesn't change what "Top Gun" or "Top Gun: Maverick" are at their core. The franchise was born in the middle of the Reagan era. Then, and now, it is a militaristic fantasy upholding the concept of white American exceptionalism. Even now, in Maverick's inclusive team, non-white characters are flanking him, rooting for him, but none rise high enough to steal his spotlight.

Like before, the mission involves the Americans taking on faceless pilots flying ambiguously identified "fifth-generation aircraft" for an unidentified rogue nation. The target is conveniently in the middle of nowhere, far enough away from any urban centers to head off distracting moralizing about civilian deaths and other collateral damage.

It's a story that very much wants to have it all ways, appealing to the broadest audience possible.

Want a daily wrap-up of all the news and commentary Salon has to offer? Subscribe to our morning newsletter, Crash Course.

But it's been a rough couple of years, and everyone's hungry for a bombastic summer flick that tickles the onions. Cruise and Kosinski target this low-key yearning by populating the movie with callbacks to the original "Top Gun," knowing how much Gen X loves its Easter Eggs and nostalgia that reminds us of our youth.

This is why nobody was expecting the opening scene of "Top Gun: Maverick" to show the title character, say, doddering around his ailing daylily farm. Cruise has a few years ahead of him before he heads the way of "The Mule," proven by the pre-movie teaser for his next great cinema conquest, 2023's "Mission ImpossibleDead Reckoning Part One."

He will be at least 60 when it comes out, and still holding the standard for refusing to age out of greatness. That fantasy doesn't belong to any party or political tribe. Claiming otherwise is simply nuts.

"Top Gun: Maverick" is now playing in theaters.

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Nanotechnology is poised to shape the future of Healthcare – ETHealthWorld

Posted: June 4, 2022 at 2:03 am

By Srinivas Iyengar

One of the most awaited technologies on the verge of moving out of laboratories and set to enter commercial production is nanotechnology. There is so much buzz about nanotechnology that industries, from cosmetics, healthcare, and automobile to aerospace, expect big disruptions due to nanotech. In the race for nano supremacy, I see healthcare as the most exciting space with a variety of use cases that can have a profound impact on humankind. In fact, nanotechnology is the most radical and wide-reaching emerging technology, and healthcare is its most urgent application.

Before we delve deeper into the application of nanotechnology in healthcare, let us take a closer look at nanotechnology, its use cases, and its market share. This will give us a clearer perspective and some critical insights into this emerging technology.

Lets understand what a nanometer is all about. To give you a better perspective, A virus, on average, is 40- 100 nanometers in size! Isnt it amazing that we are now dealing with things 1/100th the size of a virus? And these subatomic particles are making big waves today! We are building nanorobots, nanotubes, nanodots, nanowires, and nanosheets that could be used for innovative and pathbreaking medical applications from diagnosis of disease and drug delivery to the disease-affected areas of the human body with great precision, something that hasnt been actively pursued until now.

The space where nanotechnology meets healthcare is called nanomedicine. Industry experts estimate the nanomedicine market share to grow up to $260Bn in 2025 from $141Bn in 2020.

While nanostructures occur naturally in soil, dust, oceans, plants, and animals, scientists today are building nano materials with newly manipulated attributes or engineered properties. This holds massive potential and opens new doors in drug delivery systems, body scans, gene therapy, identifying cancer cells, and health monitoring.

The lexicon of Nanotechnology Before outlining the possible use cases of nanotechnology in healthcare, it would serve us well to be acquainted with the basic verbiage of nanotechnology

Nanometer (m): A nanometer is a unit of measurement which is 1 billionth of a meter. The smallest things around us are measured in nanometers. To illustrate, a DNA molecule is about 2.5 m wide compared to a red blood cell which is about 7 m.

Nanoparticles (Nanodots/Quantum dots): These are small particles that range anywhere between 1 to 100 Nm. We all know well that the smaller the material, the surface area to volume ratio increases. This ensures that nanoparticles have distinct optical, physical, and chemical properties and produce quantum effects.

Nanotubes: These are tubes with atom-thick walls and a tube-like structure mainly made of carbon materials. Nanotubes are a few nanometers wide, and their length can be up to a few millimeters. What makes them more attractive in the healthcare arena is that they are non-toxic and, therefore, safe to use.

Nanorobotics: Nanorobotics is the process of building robots at the nanoscale and such robots are called nanobots. They are typically nanoelectromechanical systems that can be programmed to carry out specific tasks.

The most promising use-cases of Nanotechnology in HealthcareIndustry experts believe that nanotechnology will play a pivotal role in shaping the future of healthcare. Lets take a look at some of its most compelling use cases that are already show promising results

Targeted Drug Delivery System: In todays conventional drug delivery mechanism, did you know that when you take a medicine for a headache, it possibly goes through your entire body, including the head, to give you relief? This also means that the drug delivery mechanism is inefficient, slow, requires more drug consumption than needed, and may impact non-targeted organs. Nanotechnology can carry drugs to specific cells and release them when it reaches the targeted organ or area. This can be highly instrumental, for instance, in curtailing the side effects of chemotherapy.

Diagnosis: A biomarker, in general, is a measurement, substance, or chemical in the body which indicates a disease or a condition. It is seen that nanotechnology can bridge the gap between measurable biomarkers representing the physiology of a biological process and clinical outcomes. Nanoparticles injected into humans can detect these biomarkers with extremely high efficacy as compared to scanning the human body from the outside, thereby reducing the chances of drug failure/rejection.

Medical Imaging: Nanoparticles/Quantum dots are so small that their surface area to volume ratio is relatively high, thus producing excellent contrast and fluoresce. In generic terms, a nanoparticle is more like a glow-in-the-dark thing, and its ability to reflect light will help us in biological labeling at the molecular level. Nanoparticles in medical devices and drug therapy can give us much better diagnosis results and treatments with a higher success rate.

Wound Treatment: One of the major pain points of wound healing is contamination with microorganisms. Silver nanoparticles have antibacterial and anti-inflammatory properties that provide better wound healing efficacy with less bacterial resistance. They can be used as scaffolds for skin regeneration. Nanofibrous materials can also be used as delivery systems for drugs, proteins, growth factors, and other molecules. This will help us in targeted drug delivery with minimal and effective drug usage.

Needless to say, there exists great scope for advancements in nanotechnology that hold the potential to revolutionize and reinvent healthcare systems despite existing hurdles. Nanomedicine, nano pharmacology, nanoimaging, and targeted drug delivery systems will make the diagnosis and prevention of diseases, and care delivery more efficient and patient-centric.

By Srinivas Iyengar, VP & Head of Healthcare & Life Sciences, Happiest Minds Technologies.

(DISCLAIMER: The views expressed are solely of the author and ETHealthworld does not necessarily subscribe to it. ETHealthworld.com shall not be responsible for any damage caused to any person / organisation directly or indirectly)

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New Silence ALS Initiative is Giving Hope to Nano-Rare Patients – BioSpace

Posted: June 4, 2022 at 2:03 am

Being diagnosed with any illness is unnerving, but imagine you are one of only 30 people in the world to suffer from the illness or at least a particular form of it. Now, imagine that that disease is 100% fatal. Thats the reality faced by the Amyotrophic lateral sclerosis (ALS) patients being treated as part of a new initiative between Columbia University and non-profit biotech company n-Lorem Foundation.

These diseases or disease mutations have been dubbed nano-rare by San Diego-based n-Lorem, whose mission is to find effective treatments for these uniquely afflicted individuals and others like them.

There are few commercial incentives for pharmaceutical or biotech organizations to pursue the discovery and development of individualized treatments, n-Lorem Chief Development Officer Sarah Glass, Ph.D. told BioSpace. The 2021 FDA guidance documents for individualized antisense oligonucleotides have enabled this non-commercial route for n-Lorems non-profit model, which is driven entirely by the desire to help patients by embedding the same level of quality that is required for standard commercial drugs."

In recent years, researchers have come to the consensus that ALS is a heterogeneous disease. This is evidenced by patient subsets that have responded favorably to drugs like Radicava, which was approved in 2017 and BrainStorm Cell Therapeutics NurOwn, which is still fighting an uphill battle for approval.

Glass said that providing a blanket definition of ALS almost does [patients] a disservice given the many unique individuals within this patient group. Individuals with ALS that carry a nano-rare mutation are often one of only a few - or perhaps the only one - that are known to have this mutation worldwide."

Lisa Stockman Mauriellofaced a similar situation. Suffering from a particularly lethal A5V mutation within SOD1-ALS, Stockman Mauriello captured the nations attention and reinvigorated the ALS community in its fight for expanded access to investigational therapies.

Stockman Mauriello was fighting for access to the experimental therapy tofersen, which was being developed by Biogen and Ionis Pharmaceuticals. Tofersen is an antisense oligonucleotide (ASO) that targets a mutation in the superoxide dismutase 1 (SOD1) gene believed to be responsible for the genetic driver in SOD1-ALS, the second most common form of inherited, or familial ALS. This category is rare itself, accounting for just 2% of all ALS cases. Ultimately, tofersen failed to achieve its endpoint in Phase III, and although Stockman Mauriello eventually did receive access to the drug, she succumbed to her disease in August 2021.

The n-Lorem-Columbia project, Silence ALS, is funded by medical nonprofit Target ALS and focuses on developing personalized experimental ASO medicines for nano-rare ALS patients. Currently, eight patients have been accepted into the program. These patients are afflicted with nano-rare mutations in either TDP-43 or CHCHD10.

In the first case, the TDP-43 protein is incorrectly ejected from the cells nucleus, preventing it from performing essential functions such as ensuring that mRNA is produced correctly, which can produce chaotic effects in affected nerve cells. Mutations in the CHCHD10 gene were identified as a genetic cause of ALS in 2014. While the process is not yet well understood, some studies suggest the mutations lead to impaired functioning of mitochondria, the cellular structures that provide the energy necessary for survival. Then, there are separate mutations within both.

These are genes that are well known in the ALS community. They are very well characterized and have been extensively studied by the research community. Unique mutations may occur in any gene and n-Lorem is learning more and more about the types of mutations and genes that ASOs can target, Glass said. The Silence ALS partnership will enable iterative learning to help the broader population over time.

She explained how ASOs can address these mutations.

These are short segments of single-stranded genetic material that bind in a sequence-specific manner to RNA to alter the behavior and performance of that target RNA. ASOs can target a specific mutation as well as different variants that uniquely differentiate that patient from others. Glass added that for some patients, it may be necessary to differentiate the disease-causing allele from the normal allele.

ALS is a progressive, neurodegenerative disease. From the time of diagnosis, a patient can expect to live between 2-5 years. During that time, they will become increasingly paralyzed, losing the ability to walk, talk, eat, swallow and finally, breathe. Glass shared that this is a big part of the reason n-Lorem teamed up with Neil Shneider at Columbia on this initiative.

The clock is ticking. One of the biggest goals of the partnership is really to introduce efficiencies such as proactive sequencing, acquiring patient cells and other elements that are required to be able to accelerate our ability to develop an individualized therapy, she said.

One of these efficiencies is ensuring that patients are characterized at an early stage in their disease prognosis. Then, the ultimate end goal would be to eventually get to the place where we can try to preempt, almost pre-symptomatically be able to develop these ASOs when the natural history of a particular mutation is known.

Glass shared that there are thousands and thousands of nano-rare diseases and patients with nano-rare mutations. Besides ALS, n-Lorem is primarily focused on helping patients with other neurodegenerative diseases as well as those with severe neurodevelopmental, ophthalmologic and kidney diseases. The foundations neurological concentration owes to it being where patients are mostly diagnosed from a genetics perspective, she explained.

Genetic testing and genome sequencing has become much more common in the rare neurological disease space and many neurologists are becoming increasingly aware of the potential of individualized therapies. This is reflected in the fact that many patients for whom n-Lorem is discovering an ASO are affected primarily by neurological manifestations. Glass said. She clarified that n-Lorem is also already developing ASOs for patients with diseases in other organ systems as well and will continue to expand the breadth of the patients it can help.

Its been understood for a while now that personalized medicine is the way of the therapeutic future, and initiatives like this one reflect that sentiment.

As genetic sequencing becomes more common, it has become apparent that more and more pathogenic mutations are nano-rare and will require individualized treatments that are out of scope for commercial organizations, she said.

Glass suggested that partnering is key to leveraging platform approaches and collective abilities to find commonalities [and therefore therapeutic efficiencies] across some of these nano-rare diseases. How can we learn and try to think across different genes, different mutations that have a number of similarities and commonalities? This could ultimately lead to the nano-rare becoming a little less rare.

Glass, who did her Ph.D. in a rare form of cancer, shared that she has always had a passion for genetics and rare diseases. Then in 2020, her own son was diagnosed with a rare disease. Being immersed in drug discovery and development and now having a child with an N-of-1 mutation as well, she wondered how one could go about successfully developing a therapy for individual patients.

At the time, I reached out to Dr. Stan Crooke [founder and CEO of n-Lorem], the pioneer of RNA-targeted drugs, she said. I immediately learned a lot and was drawn to the mission. My joining n-Lorem was an organic evolution of my career and represented the true intersection of my personal and professional passions. Since joining Crooke, Glass has been working feverishly to stand up an infrastructure to enable many more patients to be helped.

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Challenging the Standards of Care for ICI-Pretreated Patients With NSCLC – Targeted Oncology

Posted: June 4, 2022 at 2:02 am

Karen L. Reckamp, MD, explains the need for more treatment options for patients with nonsmall cell lung cancer who have been previously treated with immune checkpoint inhibitors and develop resistance.

Karen L. Reckamp, MD, a professor in Medicine, and director of the Division of Medical Oncology at Cedars-Sinai Medical Center, as well as a medical oncologist at the Samuel Oschin Cancer Center, explains the need for more treatment options for patients with nonsmall cell lung cancer (NSCLC) who have been previously treated with immune checkpoint inhibitors (ICIs) and develop resistance.

As upfront treatment for NSCLC, the majority of patients are administered immunotherapy with chemotherapy or immunotherapy alone. Although these strategies are very beneficial to patients, disease progression is inevitable, and some patients become resistant to their frontline regimen.

Once a tumor grows too large or patients are ICI refractory, no effective therapies are available. The Lung-MAP nonmatched substudy S1800A was designed to address the need for treatment option after frontline ICI therapy in patients with NSCLC. The phase 2 clinical trial (NCT03971474) investigates the combination of ramucirumab (Cyramza) and pembrolizumab (Keytruda) vs standard of care.

0:08 | All patients now receive either a combination of immunotherapy and chemotherapy or immunotherapy alone as part of their frontline treatment for advanced nonsmall cell lung cancer. We're also starting to use immunotherapy in the treatment of earlier stage nonsmall cell lung cancer. So, most patients do get exposed to immune checkpoint inhibitors at some point during their therapy. And we know though there are great benefits that patients experience most will have tumor progression and develop some tumor resistance to immune checkpoint inhibitors.

0:47 | At this moment in time, we don't have the best therapies. We don't know the best therapies to provide patients once a tumor has grown on immune checkpoint inhibition and chemotherapy. So, this study is to evaluate what might be better therapies than our standard of care which generally include

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CAR T-Cell Therapy: The New Way To Fight Cancer – Black Chronicle

Posted: June 4, 2022 at 2:02 am

Usually contained in the human physique, T cells are assigned the obligation to detect and battle threatening micro organism or viruses. T cells guard and defend our immune system. Most cancers cells are a definite story. Most cancers cells are sneaky. They duplicate and switch throughout the physique in a stealthy technique inflicting points and havoc. Sadly for the immune system, T cells are normally not always able to detect most cancers cells.

Within the earlier, there have been many challenges treating positive types of blood and bone marrow cancers along with leukemia, lymphoma, and quite a few myeloma.

That is the place CAR T-cell treatment can step in and alter the immune system paradigm.

Here is the best way it really works. Step one is to retrieve frequent T cells from the affected individual or a specific donor. The affected individual or donors blood sample goes to a lab. The T cells are then separated from the blood. A singular receptor that binds to positive proteins on most cancers cell surfaces is added to the T cells. This imported receptor is named the chimeric antigen receptor or CAR. These new and improved T cells are administered once more into the physique like a blood transfusion.

As soon as the CAR T cells enter the physique, theyll destroy cancerous cells along with tumors. The excellent news is that these modified CAR T cells will not impact healthful cells. It is a win-win situation.

In 2017, the Moffitt Malignant Hematology & Mobile Remedy program was established in partnership with Memorial Healthcare System. Oncologists now have additional decisions to take care of blood and bone marrow most cancers victims. Medical professionals can also conduct evaluation that will revenue every newly recognized and relapsed blood most cancers victims.

Malignant Hematology & Mobile Remedy at Memorial Healthcare System, located on the campus of Memorial Hospital West, is the one facility in Broward and Palm Seaside counties to provide this array of distinctive corporations and most cancers treatments.

Were at all times trying to present our group probably the most progressive and highest high quality healthcare obtainable anyplace, says Memorial Hospital West CEO Vedner Guerrier, and this development with our companions at Moffitt does that for most cancers sufferers.

CAR T-cell treatment must be considered for a number of kinds of most cancers:

Diffuse large B-cell lymphoma

Mantle cell lymphoma

Acute lymphoblastic leukemia

A number of myeloma

Follicular lymphoma

Remodeled follicular lymphoma

Major mediastinal B cell lymphoma

We see 70-80 new a number of myeloma instances every year and greater than 300 with relapse illness so, whereas not each affected person can be a CAR T candidate, were hoping many extra can be as progress continues, acknowledged Dr. Claudia Paba Prada, an assistant member of Moffitt Malignant Hematology and Mobile Remedy at Memorial Healthcare System. Were utilizing medicine underneath analysis that are not obtainable anyplace else in Florida.

Immunotherapy may be used to supply stem-cell transplants or preserve a higher top quality of life for victims who arent transplant candidates. CAR T-cell treatment can substitute or be used as a complement for chemotherapy. This implies the prospect for a lot much less toxins inside the physique all through most cancers remedy. In the long run new kinds of immunotherapies will help victims win the battle in the direction of most cancers.

For additional data, go to https://www.mhs.web/companies/most cancers/sorts/leukemia-lymphoma.

Content material provided by Memorial Healthcare System

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