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ROBERT WOOD JOHNSON UNIVERSITY HOSPITAL SOMERSET ADDS BEHAVIORAL HEALTH THERAPIST DEDICATED FOR MEMBERS OF LGBTQ+ COMMUNITY – InsiderNJ

Posted: April 19, 2022 at 2:09 am

ROBERT WOOD JOHNSON UNIVERSITY HOSPITAL SOMERSET ADDS BEHAVIORAL HEALTH THERAPIST DEDICATED FOR MEMBERS OF LGBTQ+ COMMUNITY

SOMERVILLE, NJ, April 13, 2022 Patients at the Babs Siperstein PROUD Center at Robert Wood Johnson University Hospital (RWJUH) Somerset, an RWJBarnabas Health facility, now have access to behavioral health services with a therapist dedicated to working with members of the LGBTQ+ community.

Kim Keyes, LCSW, an outpatient behavioral health therapist, has 18 years of experience as a social worker helping children and families. Keyes is available five days a week for in-person and telehealth appointments.

Ive always had a special interest in working with the LGBTQ+ community but recently decided to become more professionally involved as I have a close family member who identifies as transgender, she says. Im here to help support members of the LGBTQ+ community throughout their journey, from exploring gender identity or sexual orientation to coming out to their friends and family and learning to live fully as their true selves, which may include developing coping skills or ways to build their personal support network. This is a safe space where they can find understanding and acceptance and develop a plan to address the unique challenges they face.

Lesbian, gay and bisexual adults are twice as likely as heterosexual adults to experience mental health conditions and transgender individuals are four times as likely as cisgender individuals to experience a mental health condition, according to the National Alliance on Mental Illness. Depression, anxiety and suicide rates are also higher in the LGBTQ+ community. About 40 percent of transgender adults have attempted suicide in their lifetimes.

Coping with stigma, prejudice and discrimination can contribute to higher incidences of mental health issues among the LGBTQ+ community, Keyes says.

The transitioning process can be very stressful for transgender individuals. They are worried about how to tell others and what their reaction will be as well as anxious about starting hormone replacement therapy and considering surgical options, she says. Talking it through with someone who is supportive helps them develop healthy coping skills.

Too many members of the LGBTQ+ community suffer in silence. We are excited to be able to offer our patients convenient access to behavioral health services right here on our campus, said Perry Farhat, Esq., director of diversity and inclusion at RWJUH Somerset and director of the Babs Siperstein PROUD Center. Mental health is a key part of patients overall health and wellness.

RWJUH Somerset has been nationally recognized for providing culturally competent care and reducing health care disparities. The Human Rights Campaign has honored the hospital as a Leader in LGBTQ+ Healthcare Equality seven years in a row.

RWJUH Somerset was the first hospital in New Jersey to offer specialized primary care services for the LGBTQ+ community. The Babs Siperstein PROUD Center, which celebrates its fifth anniversary this year, offers hormone therapy and monitoring, HIV care, health education, counseling, support groups and referrals for specialty services.

Most major insurance plans are accepted. Costs for behavioral health services for uninsured LGBTQ+ patients will be covered through funding from a grant from TD Bank.

About RWJ University Hospital Somerset

Robert Wood Johnson University Hospital Somerset is a nationally accredited, 341-bed hospital in Somerville, New Jersey, providing comprehensive emergency, medical/surgical and rehabilitative services.

The hospital is nationally recognized as a Magnet hospital for nursing excellence and has earned an A Hospital Safety Score from Leapfrog its highest patient safety rating.

The Steeplechase Cancer Center at Robert Wood Johnson University Hospital Somerset has been honored with the prestigious Outstanding Achievement Award from the Commission on Cancer of the American College of Surgeons. The hospital is also distinguished for its Joint Surgery Institute, receiving the Joint Commissions Gold Seal of Approval for total knee and total hip replacement surgery, and is designated as a Primary Stroke Center by the Joint Commission and the New Jersey Department of Health and Senior Services. Robert Wood Johnson University Hospital Somerset has been named a Center of Excellence in Metabolic and Bariatric Surgery by the Surgical Review Corporation. In addition, it has received the Joint Commissions Gold Seal of Approval for its acute myocardial infarction program.

Honored as a Leader in LGBT Healthcare Equality by the Human Rights Campaign, the hospital was the first in New Jersey to offer primary care services for the LGBTQIA community.

Robert Wood Johnson University Hospital Somerset also offers outpatient services at convenient locations in Central New Jersey, including physical therapy services in Bedminster, Bridgewater, Hillsborough, Princeton and Flemington and an urgent care center and a sleep disorders center in Hillsborough. In addition, the hospitals affiliated physician practices provide care for families throughout its community.

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ROBERT WOOD JOHNSON UNIVERSITY HOSPITAL SOMERSET ADDS BEHAVIORAL HEALTH THERAPIST DEDICATED FOR MEMBERS OF LGBTQ+ COMMUNITY - InsiderNJ

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‘I’m 43 and just married my much younger husband. It’s made me worried about ageing.’ – Mamamia

Posted: April 19, 2022 at 2:09 am

Id heard that your experience of menopause is often similar to your mothers, but my mum had already had a hysterectomy by my age. Shed been placed on the old form of Hormone Replacement Therapy (HRT) and then slipped quietly into post-menopause.

I didnt even notice, she said. Would that be my experience too?

I opened the book and couldnt put it down. I read it in three days, and the more I read, the more excited I got. I looked up every site the book recommended. I joined three perimenopause and menopause Facebook groups. I watched TED Talks. I was hooked.

Listen to The Quicky's episode on menopause. Post continues after podcast.

I talked with dozens of women and devoured their stories, the good ones and the awful ones. I wanted to hear about every symptom, every stage, every treatment. I learned about the new Menopausal Hormone Therapy (MHT) and looked up specialists to readtheir recommendations. I found podcasts and blogs and more books.

It felt like being let in on a secret - one I no longer found scary, but empowering. I brought up menopause with every single person I met: the hairdresser, friends at a barbecue, my sisters, my chiropractor, my doctor. Did other people know what I knew?I had to find out.

My husband listened attentively to way more than he probably cared to hear.

I wanted to make sure everyone had heard about perimenopause because to me, and many of the women I interviewed, it had been such a mystery.

The chiropractor and the doctor had only briefly heard about it in their training.

Ive always felt like I was missing something with my women patients. Like I was treating disconnected symptoms I knew were somehow connected, the chiropractor said.

The doctor, a young man who was trained within the last decade, said theyre taught almost nothing about menopause at medical school, unless theyre specifically interested in the topic. Nothing at all about perimenopause.

Its strange how little were told, considering its not rare, he said. Half the population will go through it.

I told my husband what hed said.

Well, its not a very sexy topic, he replied.

I stared at him. Seriously? Dont judge him too harshly here. I didnt. My husband is usually a smart manand this topic is new for him too. I decided to hold my tongue.

Bowel cancer isnt sexy and they learn about that.

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Tucker Carlsons answer to masculinitys supposed crisis? Testicle tanning – The Guardian

Posted: April 19, 2022 at 2:08 am

Are there three words in the English language that can strike quite as much trepidation into the hearts of the sane and rational person as Tucker Carlson original? Yes, the documentary strand that brought you such titles as Hungary vs Soros: The Fight for Civilization and Patriot Purge, a BS-laden fantasy about the January 6 riots that contained so many bonkers claims about false-flag operations that it forced a tranche of Fox News veterans to quit the network, has returned.

The latest addition to the Carlson oeuvre is called The End of Men and its Magic Mike-style trailer just dropped.

It begins with a familiar Make America Great Again-style montage, centering on a John F Kennedy speech in which he extols the virtues of strength and exercise and berates Americas soft, chubby fat-looking children. Quickly, Kennedys reasonable-for-the-time approach to childhood obesity is equated with a precipitous decline in sperm counts and testosterone over the last 50 years.

And then what could only be described as a series of money shots. As the booming timpanis of a Richard Strauss piece from 2001: A Space Odyssey swell we see huge buff topless men, cutting wood, milking cows, firing guns, barbecuing, fighting, drinking egg yolks and most strikingly, tanning their genitals. This supposed sequence of real red-blooded males is perhaps the campest thing Fox News has aired since Glenn Beck doused a handsome model in gasoline.

Carlsons deeply homoerotic version of real men looks more xVideos than ex-mining town but the testosterone-based view of masculinity hes pushing has been a common theme for Fox News over the past decade, and a profitable one.

The testicle tanning, or red-light therapy, shown in the video is explained further in an interview Carlson does with a self-proclaimed bromeotherapy expert. He claims that by dousing your balls in red LEDs, you can create higher levels of testosterone.

The potential for UV or red light to increase testosterone levels has been quite well documented but there are no peer-reviewed double-blind studies that are able to prove these claims. Testosterone levels also change dramatically throughout the day, and also see dramatic increases from exercise, new sexual partners and changes to diet.

Its no surprise to see Fox News suggest that the answer to all of mankinds problems are testosterone related. The channel is heavily invested in the idea that a decrease in testosterone is making men more liberal and less masculine, and many of its remaining advertisers sell pills that promise to increase mens testosterones levels.

I spent some time reporting this story three years ago, that testosterone was becoming heavily politicised, particularly by Trump-supporting radio hosts who equated liberalism to having low T (one rightwing radio doctor even offered a free testosterone test to any listener thinking about voting for Hillary Clinton). The US is awash with ads for testosterone supplements that make a similar claim, many of them airing on Fox News. Trump himself used to insinuate that his opponents were tired and had low T.

Many men are injecting themselves with testosterone with political motivations but in reality the idea that testosterone is the male hormone and oestrogen is the female one is wrong. Both men and women have both hormones, at highly varied levels, and most men have far more testosterone than they need (indeed, testosterone, which is critical to heart function, is often converted into oestrogen, which means that people who routinely inject testosterone often end up growing breasts). Low testosterone can make some men feel tired and impotent and they need replacement therapy, but others get by on low levels of blood testosterone just fine.

Carlson is right that sperm counts and overall testosterone have been decreasing over the last 50 years due to lifestyle changes including rising obesity. But the idea that this in some way is a problem of manliness, and that if only we tanned our balls men would become happier, is patently untrue.

The show is also a reflection of how far Carlson has shifted into the world of pseudo-scientific and bezerk solutions in the past few years. Just four years ago he was still talking about falling testosterone levels but as part of a wider soul-searching about men in America, doing pieces about why men were more likely to kill themselves, commit mass shootings, be incarcerated, be medicated as children and are performing worse by some educational measures. In the video above, Carlson takes a rightwing anti-feminist position but at least makes some reasonable points about the problems facing American men.

Since then Carlson has fallen off a deep end of trolling and insanity and would rather entertain wild medical interventions than political change. Perhaps hed be happier doing some red light therapy instead of his nightly red face therapy.

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Advancements of CAR-T Cell Therapies Importance Grows While Cancer Cases Increasing – PR Newswire

Posted: April 19, 2022 at 2:07 am

PALM BEACH, Fla., April 14, 2022 /PRNewswire/ -- FinancialNewsMedia.com News Commentary - CAR-T therapy is a sort of treatment in which a patient's T cells which is a type of immune system cell, are genetically modified to attack cancer cells in the lab. T cells are extracted from the blood of a patient. The gene for a specific receptor that binds to a specific protein on the patient's cancer cells is then transferred to T cells in the lab. A chimeric antigen receptor is a unique type of receptor (CAR). CAR-T units are generated in large numbers in the lab and then infused into the patient. CAR-T therapy is used to treat specific types of blood malignancies, and it is also being researched for other cancers. CAR T therapy is also known as Chimeric antigen receptor T-cell therapy. T cells are used in CAR T therapy since they are generally responsible for destroying malignant cells and virus-infected cells. Cancer cells are known to hide from the immune system, but scientists have been able to improve T cells' ability to locate and kill cancer cells using CAR T therapy. A report from Polaris Market Research projected that the global CAR-T cell therapy market was valued at USD 1,965.8 million in 2021, expected to grow at a CAGR of 31.16 % during the forecast period (2029). The report said: "CAR T therapy market is expected to grow due to the growing prevalence of cancer cases across the globe. This treatment has captured the attention of researchers and the public because of the remarkable responses they have produced in patients. The Food and Drug Administration (FDA) approved two CAR T treatments in 2017, one for children with acute lymphoblastic leukaemia (ALL) and the other for adults with advanced lymphomas." Active biotech and pharma companies in the markets this week include Oncolytics Biotech Inc. (NASDAQ: ONCY) (TSX: ONC), Sierra Oncology, Inc (NASDAQ: SRRA), Antares Pharma, Inc. (NASDAQ: ATRS), Clovis Oncology, Inc. (NASDAQ: CLVS), Turning Point Therapeutics, Inc. (NASDAQ: TPTX).

"Continuous growth has been witnessed in biotechnology and life science sectors for the treatment of cancer using chimeric antigen receptors. Increased patient assistance programs (PAPs), increased government activities for cancer awareness, rising cancer prevalence worldwide, and strong R&D initiatives from key companies are all driving CAR-T cell therapy market expansion. With the growing need for cell-based therapy, producers have started investing in the manufacturing of this therapy. North America is expected to dominate the global CAR-T cell therapy market due to the increasing cancer cases and growing emergence of the biotechnological sector. North America is witnessing an increasing number of cancer cases which is increasing the market demand for cancer therapies in the region The presence of key players in the region are focusing on expanding their global presence, is fueling the CAR-T cell therapy market."

Oncolytics Biotech Inc. (NASDAQ: ONCY) (TSX: ONC) BREAKING NEWS: Oncolytics Biotech Announces Publication of Preclinical Data Demonstrating the Synergistic Anti-Cancer Activity of Pelareorep Combined with CAR T Cell Therapy in Solid Tumors in Science Translational Medicine- Oncolytics Biotech today announced the publication of preclinical data demonstrating the synergistic anti-cancer activity of pelareorep combined with chimeric antigen receptor (CAR) T cell therapy in solid tumors. The paper, entitled "Oncolytic virus-mediated expansion of dual-specific CAR T cells improves efficacy against solid tumors in mice," was published in Science Translational Medicine in collaboration with researchers at several prestigious institutions, including the Mayo Clinic and Duke University. A link to the paper can be found by clicking here.

"Having these results published in such a high-impact journal provides important external validation of their significance," said Thomas Heineman, M.D., Ph.D., Chief Medical Officer of Oncolytics Biotech Inc. "While CAR T cells have generated long-term cures in hematologic malignancies1, the immunosuppressive tumor microenvironments (TMEs) of solid organ cancers have thus far limited their efficacy in these indications. Pelareorep has repeatedly been shown to reverse immunosuppressive TMEs, and in the present publication pelareorep is shown to enable the effectiveness of CAR T cells in multiple murine solid tumor models. This is a powerful finding that, if translated to the clinic, could significantly improve the prognosis of patients with a variety of highly prevalent cancers by providing a novel and potentially durable treatment option. By demonstrating the ability to improve T cell perseverance, reduce antigen escape, and overcome challenging solid tumor TMEs, the inclusion of pelareorep addresses the three most challenging roadblocks to effective CAR T therapy."

Andrew de Guttadauro, President of Oncolytics Biotech U.S. and Global Head of Business Development, added, "Despite revolutionizing the treatment of certain cancers and surpassing a billion dollars in sales last year, CAR T therapies currently only serve a small subset of patients suffering from hematologic malignancies. With these latest results, we now have strong preclinical evidence that pelareorep can fully unlock the value of CAR T therapies by expanding their commercial potential to the significantly larger market of cancer patients who are battling solid tumors."

Preclinical studies published in the paper evaluated the persistence and efficacy of pelareorep-loaded CAR T cells ("CAR/Pela therapy") in multiple murine solid tumor models. The effects of combining CAR/Pela therapy with a subsequent intravenous dose of pelareorep ("pelareorep boost") were also investigated. Key data and conclusions from the paper include:

Dr. Matt Coffey, President and Chief Executive Officer of Oncolytics Biotech Inc. and co-author of the paper commented, "These exciting results are an excellent example of how we are leveraging collaborations with key opinion leaders and premier research institutions to broaden pelareorep's potential therapeutic impact. This allows us to remain primarily focused on our lead breast cancer program, which has shown how pelareorep's ability to promote tumor T cell infiltration leads to synergy with checkpoint inhibitors in the clinic. These newly published preclinical findings show pelareorep's synergistic benefits extend even beyond checkpoint inhibitors and highlight an opportunity to increase our addressable patient population. As we pursue this opportunity moving forward, we intend to utilize relationships with academic or industry partners so that we can continue to execute on our clinical and corporate objectives with efficiency." CONTINUED Read this full press release and more news for ONCY at: https://www.financialnewsmedia.com/news-oncy/

Other recent developments in the biotech industry of note include:

GlaxoSmithKline plc (NYSE: GSK) and Sierra Oncology, Inc (NASDAQ: SRRA)recently announced that the companies have entered into an agreement under which GSK will acquire Sierra Oncology, a California-based, late-stage biopharmaceutical company focused on targeted therapies for the treatment of rare forms of cancer, for $55 per share of common stock in cash representing an approximate total equity value of $1.9 billion (1.5 billion).

Myelofibrosis is a fatal cancer of the bone marrow impacting the normal production of blood cells. Anaemia represents a high unmet medical need in patients with myelofibrosis. At diagnosis, approximately 40% of patients are already anaemic, and it is estimated that nearly all patients will eventually develop anaemia.Patients treated with the most commonly used JAK inhibitor will often require transfusions, and more than 30% will discontinue treatment due to anaemia.Anaemia and transfusion dependence are strongly correlated with poor prognosis and decreased overall survival. Momelotinib has a differentiated mode of action with inhibitory activity along key signalling pathways.

Antares Pharma, Inc. (NASDAQ: ATRS) recently announced that the U.S. Food and Drug Administration granted final approval for TLANDO (testosterone undecanoate), an oral treatment for testosterone replacement therapy ("TRT") indicated for conditions associated with a deficiency or absence of endogenous testosterone, or hypogonadism in adult males.

Robert F. Apple, President and Chief Executive Officer of Antares Pharma, commented, "The FDA approval of TLANDO brings to market an oral formulation of testosterone that we believe will prove beneficial to physicians and their patients. We have recently expanded our commercial organization to 108 sales representatives and expect to leverage our relationships with urologists and endocrinologists to drive adoption of TLANDO. This approval also reinforces the opportunity for Antares to continue to drive share gains in the TRT market with both TLANDO and XYOSTED and support our future growth with an expanded commercial portfolio.

Clovis Oncology, Inc. (NASDAQ: CLVS), recently announced that two abstracts featuring non-clinical data from studies evaluating FAP-2286 and Rubraca and a Trial-in-Progress poster detailing the Phase 1 portion of the LuMIERE study will be presented at the upcoming American Association for Cancer Research (AACR) Annual Meeting 2022, being held April 8-13, 2022, in New Orleans.

In a new non-clinical data analysis, FAP-2286 demonstrated potent affinity for human fibroblast activation protein (FAP) by biochemical and cell-based assays. Additionally, lutetium-177 (177Lu)-FAP-2286 showed longer tumor retention, resulting in greater tumor inhibition as compared to lutetium-177 (177Lu)-FAPI-46, a FAP-targeted radiotracer developed for therapeutic applications at the University of Heidelberg, Germany.

Turning Point Therapeutics, Inc. (NASDAQ: TPTX), a clinical-stage precision oncology company developing next-generation therapies that target genetic drivers of cancer, recently announced positive topline results from the registrational TRIDENT-1 study across all fourROS1-positive advanced non-small cell lung cancer (NSCLC) cohorts, as reported by Blinded Independent Central Review (BICR).

"We are very encouraged by the topline results from the pooled Phase 1 and Phase 2 portions of TRIDENT-1 by BICR shared today and continue to believe repotrectinib is a potentially best-in-class drug candidate for patients withROS1-positive advanced NSCLC," said Athena Countouriotis, M.D., President and Chief Executive Officer. "The confirmed ORR data and 95% confidence intervals across all four cohorts remain strong, and the initial estimated Kaplan-Meier landmark analyses based on limited median follow-up of approximately 10 months for both duration of response and progression free survival in the TKI-nave population are trending in the direction we had hoped for given this is the highest area of unmet medical need. We believe a differentiated profile is built upon a strong ORR and durability of response that could improve upon the current standard of care."

DISCLAIMER: FN Media Group LLC (FNM), which owns and operates FinancialNewsMedia.com and MarketNewsUpdates.com, is a third party publisher and news dissemination service provider, which disseminates electronic information through multiple online media channels. FNM is NOT affiliated in any manner with any company mentioned herein. FNM and its affiliated companies are a news dissemination solutions provider and are NOT a registered broker/dealer/analyst/adviser, holds no investment licenses and may NOT sell, offer to sell or offer to buy any security. FNM's market updates, news alerts and corporate profiles are NOT a solicitation or recommendation to buy, sell or hold securities. The material in this release is intended to be strictly informational and is NEVER to be construed or interpreted as research material. All readers are strongly urged to perform research and due diligence on their own and consult a licensed financial professional before considering any level of investing in stocks. All material included herein is republished content and details which were previously disseminated by the companies mentioned in this release. FNM is not liable for any investment decisions by its readers or subscribers. Investors are cautioned that they may lose all or a portion of their investment when investing in stocks. For current services performed FNM expects to be compensated forty nine hundred dollars for news coverage of the current press releases issued by Oncolytics Biotech Inc. by a non-affiliated third party. FNM HOLDS NO SHARES OF ANY COMPANY NAMED IN THIS RELEASE.

This release contains "forward-looking statements" within the meaning of Section 27A of the Securities Act of 1933, as amended, and Section 21E the Securities Exchange Act of 1934, as amended and such forward-looking statements are made pursuant to the safe harbor provisions of the Private Securities Litigation Reform Act of 1995. "Forward-looking statements" describe future expectations, plans, results, or strategies and are generally preceded by words such as "may", "future", "plan" or "planned", "will" or "should", "expected," "anticipates", "draft", "eventually" or "projected". You are cautioned that such statements are subject to a multitude of risks and uncertainties that could cause future circumstances, events, or results to differ materially from those projected in the forward-looking statements, including the risks that actual results may differ materially from those projected in the forward-looking statements as a result of various factors, and other risks identified in a company's annual report on Form 10-K or 10-KSB and other filings made by such company with the Securities and Exchange Commission. You should consider these factors in evaluating the forward-looking statements included herein, and not place undue reliance on such statements. The forward-looking statements in this release are made as of the date hereof and FNM undertakes no obligation to update such statements.

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Gilbert Gottfrieds myotonic dystrophy: 5 things to know about the rare genetic disorder – cleveland.com

Posted: April 19, 2022 at 2:07 am

CLEVELAND, Ohio Stand-up comedian and actor Gilbert Gottfried, who died this week at 67, lived for years with the rare genetic muscle disorder myotonic dystrophy type 2, a common form of muscular dystrophy.

The cause of death was recurrent ventricular tachycardia, a heart condition, his longtime friend and publicist Glenn Schwartz announced.

Gottfried, known for his distinctive voice, was a cast member on Saturday Night Live, and the wisecracking parrot Iago in the animated Disney film Aladdin, among other roles.

Here are five things to know about myotonic dystrophy, with information provided by Med Page Today, the Myotonic Dystrophy Foundation and the Cleveland Clinic.

1. What is myotonic dystrophy?

Myotonic dystrophy is a rare, inherited disease that affects the muscles and other body systems. It is usually diagnosed in adulthood, often when a person is in their 20s or 30s. In this disorder, muscles throughout the body are unable to relax after they contract.

The condition is classified into two types: myotonic dystrophy type 1 (DM1), sometimes called Steinert disease, and myotonic dystrophy type 2 (DM2).

DM2 is generally considered less severe than DM1 -- though symptoms may vary among patients.

2. What causes it?

Myotonic dystrophy is usually caused by a gene mutation. It can be passed on by a family member, but may occur without a family history of the illness. People living with myotonic dystrophy have a 50% chance of passing on the mutated gene to their children.

3. What are the symptoms?

Symptoms include problems with muscles, heart, breathing, digestive system, hormonal, speech, swallowing, diabetic, immune system, vision, daytime sleepiness and cognition. Different people can have different symptoms.

The DM2 that Gottfried had is characterized by muscle weakness, wasting and pain. Muscles in the neck, fingers, elbows and hips are typically affected.

While the diseases rate of progression can vary, symptoms generally progress slowly.

4. How is it treated?

There are no treatments or cure available. Patients manage symptoms in a variety of ways, such as wearing ankle-foot braces, using a wheelchair, having cataracts removed or undergoing testosterone replacement therapy.

An implantable cardiac defibrillator devices that monitor the heart rate and send an electric pulse or shock to the heart to restore a normal heartbeat may be used to treat heart arrhythmias.

5. How many people have myotonic dystrophy?

It affects an estimated 1-in-2,100 people, or more than 3.6 million people globally. The muscular dystrophies as a whole are estimated to affect 250,000 Americans.

For more information:

Myotonic Dystrophy Foundation

Muscular Dystrophy Association

National Organization for Rare Disorders

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Gilbert Gottfrieds myotonic dystrophy: 5 things to know about the rare genetic disorder - cleveland.com

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Lia Thomas started a conversation about transgender rights. It’s time we dive into it. – The Emory Wheel

Posted: April 19, 2022 at 2:07 am

The Eagles swim against the University of North Carolina (UNC)-Wilmington in the WoodPEC in 2014. (Courtesy of Jason Oh)

Following the end of University of Pennsylvania swimmer and transgender woman athlete Lia Thomas collegiate career in March, the subsequent wave of nationwide anti-trans athlete legislation has jeopardized the future of inclusion in sports. But while the world becomes increasingly embroiled in legislative battles designed to maximize exclusion, the nuances of the controversiality of fairness and inclusion have been swept to the wayside.

Thomas broke barriers as the first trans female athlete to win a title at the NCAA Swimming and Diving championships. Despite following NCAA policy and undergoing over two years of hormone replacement therapy (HRT), she endured hate from not only her teammates, but also politicians and avid swim fans arguing about her eligibility. The uproar of concern about compromising the integrity and fairness of womens sports could be labeled as transphobic and for some, it certainly comes from a place of bigotry. But perhaps the arguments also stem from our curiosity surrounding the creation of the policy and how we reconcile existing laws with a future in which binary classifications no longer apply.

After consulting with athletes, sports organizations and medical experts in 2015, the International Olympic Committee (IOC) determined that while transgender men can take part in competitions without any restrictions, testosterone levels of transwomen must be below 10 nanomoles/liter for at least one year prior to competing. Later in 2021, however, the guidelines were adjusted to consider hyperandrogenism, a medical condition commonly affecting more women than men, which may result in higher testosterone levels irrespective of HRT. Instead of an overarching criteria for all athletes, IOC now shifts to an evidence-based, sport-specific framework where the data must strongly suggest a consistent, unfair, disproportionate competitive advantage. While the change is a step forward in the right direction, defining a disproportionate advantage remains vague and is not conducive to conversation.

Current political debates emphasize the most widely accepted definition of inclusion and equity: that all people, regardless of gender identity or expression, be afforded the same chances and opportunities. Transgender folks deserve the same basic respect as those who conform to now outdated gender binary classifications. At the same time, failing to consider the biological differences such as lean body mass, pelvic width and lung capacity neglects the full story.

Physicality is undeniably a more pertinent factor in sports than in other aspects of life. The innately different build of cisgender men offers them a significant and often insurmountable competitive advantage over women. For instance, men have a longer and larger bone structure which supports more powerful muscles and a wider frame. Their high muscle mass to body-weight ratio also gives men a noticeable advantage in speed-based competitions. In sports such as swimming, where athletes race against the clock and one another, female records will always be slower than male ones.

Different body compositions are advantageous in different sports, and forcing the same sweeping ban on all athletes would not be equitable or fair. Body composition can be measured by a number of factors, namely body fat and the ratio of strength-to-mass. While lower body fat and higher levels of lean body mass might benefit weightlifters, boxers and footballers, this body type doesnt necessarily work for everyone. Many distance runners and track athletes would be faster with lower body fat as it reduces air drag. Higher strength-to-mass ratios like martial artists and gymnasts have may hold their bodies up with more ease and better counteract the effects of gravity. But for swimmers, its not as clear cut. Body fat may be more buoyant, but too much concentrated in one area will lead to drag. Too much lean body mass may also result in sinking. Optimal body composition is not universal, so we shouldnt treat everyone the same way either.

In Florida, Texas and other traditionally right-leaning states, legislators have recently passed laws forcing public school students to only compete on sports teams based on the sex they were assigned at birth. The policies continue, despite a persisting lack of research and evidence indicating that innate biological differences give trans athletes a significant advantage. I would be remiss not to consider the nuance behind the substantial physical advantages of trans female athletes. HRT may increase body fat and decrease lean muscle mass. But with a lack of research, it is unclear how long it takes for this to occur, and to what extent it will affect the bodies of trans athletes and subsequently, their swimming technique.

Its foolish to dismiss such stark time differences during formal competitions. For the duration of the 2021-2022 season and at the 2022 Ivy League Womens Swimming and Diving Championships, Thomas competed on the womens team; at the championships, she won the 200 freestyle with a time of 1:43.12. The top finisher on the mens side, Dean Farris from Harvard University (Mass.), finished in 1:32.67. In many parts of life, nine seconds isnt much: being nine seconds late to class or taking nine seconds to remove a pie from the oven is inconsequential. But in swimming, especially on an elite level such as the NCAA, being nine seconds slower could cause an athlete to fall behind by nearly an entire pool length.

Striving to bridge the gap between the divisiveness of transgender policies in sports is an admirable goal, but it grows complicated when we continuously try to consolidate contradictory research claims on sex and gender. For instance, HRT, which transgender women sometimes use to lower their testosterone levels, can be an essential part of the transition process for transgender people. It not only has beneficial physical effects, such as blocking testosterone or increasing estrogen, but also has psychological effects like mitigating gender dysphoria. On the other hand, a 2018 study also claimed that medicine would be unable to completely suppress testosterone levels in about 25% of the transgender women who participated in the study. Another quarter of trans women were able to lower testosterone levels, whereas another quarter could not reach typical female levels but remained below typical male testosterone values.

Scientific research, raging pundits and international sports committees on both sides of the debate have all put forth opinions and claims that often contradict with another. The effects of HRT and studies on hormones are still relatively new. Coming to a consensus on fair policies requires more than just political squabbling. No one can seem to propose a solution that is both equitable and inclusive, and I still have several unanswered questions: how long should an individual have to undergo HRT to be considered athletically equivalent to a cisgender women? How should fairness be defined in sports is it about unequivocal inclusion or about ensuring equal competitive opportunity? Do trans female athletes have a significant competitive advantage over cisgender women and, if so, to what extent? Hopefully, with more research and involving transgender people in these discussions, we will be able to answer these questions and reconstruct fairness in sports.

I must admit that the news of Thomas record-breaking swims perplexed me, likely for the same reasons it has angered elite athletes: how could it ever be fair? At the same time, I cant help but be in awe and admiration of the time and effort Thomas must have spent training in order to win so definitively in the face of so much vitriol.

Truly, asking Thomas to give up swimming or banning her from the sport would be a devastating blow. For any elite athlete, the dedication, passion and love they have for a sport is ingrained in their identity. Taking those opportunities away because of someones gender expression or identity fails to coincide with the spirit of sportsmanship we try to teach. Continuous accusations of injustice to womens sports come from desperation, to be part of a fight for or against Thomas and all other trans athletes. The true root of the issue lies with clumsy, contradictory and uninformed legislative and administrative voices unwilling to do any research that might unravel their biases.

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Who are the teens at the center of the legal fight over Alabamas law banning transgender treatment? – AL.com

Posted: April 19, 2022 at 2:07 am

Parents of four teens suing Alabama over its ban on treatment for transgender minors say the new law will drastically change their kids lives, taking them from happy teenagers back to their lives of depression and confusion they faced before starting treatment and leaving them a shell of themselves.

At least two federal lawsuits have been filed since Alabama Gov. Kay Ivey signed a law last week making it a crime for transgender minors to receive gender-affirming medical treatment. The new law goes into effect May 8.

The standard of care for gender dysphoriathe clinical diagnosis for when a persons gender identity doesnt match their birth sextypically includes treatments like puberty-blocking medication, hormone-replacement therapy, and surgical treatment. Doctors and experts say no gender-affirming surgeries are performed on transgender minors in the state of Alabama.

One lawsuit was filed in the Northern District of Alabama by the families of two transgender teens and two Childrens of Alabama and University of Alabama at Birmingham doctors. The other suit was filed in the Middle District of Alabama by two different families of trans teens.

Teens in the first federal suit, filed in Birmingham, are identified under the pseudonyms Mary Roe and John Doe. The second lawsuit, filed in Montgomery, lists the plaintiffs as teenagers identified by their initials, H.W. and C.W.

These are not random kids. These are kids in your communities who will suffer tremendously, said Asaf Orr, an attorney with the National Center for Lesbian Rights, which is one of the groups representing the parents and their children.

A spokesperson for the governors office said, We are prepared to defend our Alabama values and this legislation. The Alabama Attorney Generals Office did not respond to requests for comment.

Heres what we know about the teenagers who are fighting Alabamas new law based on the lawsuits:

Mary Roe

Mary, 13, is a transgender girl in Jefferson County. She started showing symptoms of gender dysphoria from a young age and began to tell her family that she was a girl starting around age 6. After seeking therapy and advice from medical professionals, Mary started to dress like a girl and her mental health greatly improved.

Following issues at school the next year with her new gender identity, Marys parents enrolled her in a new school, where Mary was allowed to dress like a girl and go by her new name. Since Marys transfer to the new school, she has returned to being the happy, active child she was during the summer prior to first grade, the lawsuit suit states.

In early 2021, Marys pediatrician evaluated her for puberty blockers. She began taking the medicine in April 2021 and has been taking it since.

It is essential for Marys mental health that she continues to receive puberty-blocking medications every three months and is able to obtain any future medical treatments that her healthcare providers determine are medically necessary to treat her gender dysphoria, her lawsuit states. For Mary to be forced to go through male puberty would be devastating; it would predictably result in her experiencing isolation, depression, anxiety, and distress. Marys parents are also concerned that without access to the puberty-blocking medication she needs, Mary would resort to self-harm as a means of coping with her psychological distress or even attempt suicide.

If the law goes into effect on May 8, Mary will have to stop her medication.

Without access to puberty-blocking medication, Marys body will produce testosterone, and she will begin to develop secondary sex characteristics associated with males. The changes to Marys bodysome of which would be permanent or would require surgery to reversewould make visible to others that she is a transgender girl and would cause her to experience again the distress she experiences from having a body seen by others as inconsistent with her female identity.

John Doe

John, a 17-year-old in Shelby County, also began showing symptoms of gender dysphoria at a young age. While his parents thought the behavior was a phase, they were accepting. He began to see a therapist when he was about 8. While it helped at first, the suit said Johns mental health declined when he started puberty.

He quickly developed large breasts, which was very distressing for John. He would often cry in the shower because of the shape of his chest, wear multiple sports bras at a time, and slouch his shoulders to make the appearance of his chest less prominent, the lawsuit said. Getting his period was equally distressing for John. Johns dysphoria was so severe that he stayed home from school for at least one day each month.

When John was in high school, he told his parents he was transgender. With the help of his parents, John connected with mental health and medical providers at UAB. He started medication to stop his period and, about a year later, he started testosterone treatments.

Starting testosterone has been amazing for John, his lawsuit states. He finally is feeling more like himself, building greater confidence, and is happier overall. Over the past year and a half, Johns voice has dropped, and he has developed facial hair. Those features have allowed him to feel more comfortable in his body and eased his anxieties about not being treated as a male by others.

John will also be forced to stop his medications if the law goes into effect, leading to what the legal team calls devastating physical and psychological consequences.

The stories of Roe and Does experiences are the norm for transgender minors, Orr said, and the new law means parents cant be in charge of their childs medical decisions.

That should be frightening to people who identify as political conservatives, he said.

H.W.

A transgender 15-year-old, H.W., came out to her parents as trans at 10. She began her social transition soon after and legally changed her name and altered her clothing and appearance. Those changes were very helpful to H. W., but she remained terrified about what would happen when she started puberty, as she could not imagine having a body like a teenage boy, the lawsuit states.

At the recommendation of her multiple doctors and after evaluations, H.W. started puberty-suppressing medicine at 12. The treatment has prevented H. W. from having to undergo a puberty that would cause changes in her body- some irreversible- that would severely exacerbate her gender dysphoria. By allowing H. W. to pause puberty and not experience the physical changes that terrified her, puberty-suppressing medication has significantly improved H.W. s health, according to the lawsuit.

She is also set to begin hormone therapy in the fall.

Growing up in a body that did not match who she was made H.W. miserable, lawyers said in the suit. Accessing medical care has been transformative for H.W. She became less shy and more confident and began thriving in school.

Without H.W. s puberty-suppressing medication, she would be forced to undergo a typical male puberty, which would cause her to develop a deep voice, a typically masculine jawline, an Adams apple, hair growth on her body, and a broadening of her shoulders. The changes are potentially irreversible, the suit said, and would cause H.W. to not feel like herself anymore, and cause her to likely be bullied.

H.W.s family would have to leave Alabama if the law goes into effect, the suit said, leaving her parents without work and splitting her apart from her siblings.

C.W.

C.W., 13, is a transgender girl who first told her parents about her severe stress and anxiety at 9, and soon after came out as trans. After sharing her new pronouns and name with those around her, the lawsuit said, C.W.s outlook, demeanor, and overall well-being immediately improved.

When she was in fourth grade in 2018 and asked people at school to call her by her new name, there were incidents of bullying and harassment, which lasted several years. In 2019, her parents legally changed her name and submitted the legal name change to the school.

At 11, C.W. consulted with a team of doctors and was diagnosed with gender dysphoria. Later that year, she started puberty suppressing medication. According to the lawsuit, the medicine has made an incredible difference in C.W.s life. She, too, would suffer possibly irreversible changes to her body if she stopped the medications.

C.W. s parents are concerned that without her medical treatment, C.W. s confident self would fade away, the suit said, adding her family would consider moving out of Alabama and leaving behind their families, support networks and jobs.

Claims

Both lawsuits say the teens are being denied medical treatments and taking the decision out of the hands of doctors and parents.

The (law) abandons science and seeks to stop safe, effective, and medically necessary treatments for children with gender dysphoria in Alabama without any rational basis, the Doe and Roe lawsuit states. The law also ignores established medical science.

Doctors and parents of transgender minors are forced to choose between withholding medically necessary treatment from their minor transgender patients or children, on the one hand, or facing criminal prosecution, on the other, that lawsuit adds.

Orr and lawsuits also point out the treatments themselves are not bannedif another minor needed puberty blockers or hormone therapy for issues that were not related to gender dysphoria or being transgender, they could receive them. Orr said thats a clear discrimination based on sex.

RELATED: Alabama schools chief: Teachers could have to navigate tricky conversations after new law - al.com

Neil Rafferty, Alabamas only openly gay legislator: Why cant we just let people live their lives in this state?

Alabama families with transgender children crowdsource to flee to safer state for medical care

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In Venice, a Young Boatman Steers a Course of His Own – The New York Times

Posted: April 19, 2022 at 2:07 am

VENICE, Italy From the time he was a child, Edoardo Beniamin could envision paddling a gondola through the waterways of Venice, his native city. He saw himself, dressed in a striped jersey and ribboned straw hat, following his father and an uncle into a profession that has served as the enduring symbol of La Serenissima for a thousand years.

To be a gondolier was always my dream, Mr. Beniamin, 22, said one bright winter day in a Venice rendered vacant by a wave of Covid-19 sweeping across Europe.

Seated at an outdoor cafe near the San Zaccaria waterbus station on the Grand Canal, Mr. Beniamin explained why his childhood imaginings had felt to him unrealistic. In the gondola business, it matters a lot if you are the son of someone, he said. But I really didnt think it could be possible, since girls could not do it.

A slight man with a thatch of coppery hair and facial scruff, Mr. Beniamin was assigned female at birth. For the first 16 years of his life, he said turning up the collar of his shearling jacket against the chill he had not felt a need to call that into question.

When I was very very young lets say, 6 or 7 I wanted to be a man but it was more for fun, he said. I preferred boys clothes, for example, and I used to say these things I want to dress like a man that were not serious. I thought I was a girl and so I forgot all about it.

Five years ago, while still in high school and dating his girlfriend Claudia Nardelli, now 22 and his fiance he experienced what some in the trans community term an egg moment, an emergence. He began questioning whether the crippling migraine headaches and related health complaints that plagued him, most notably after gym class and that led his mother to take him from one doctor to another had origins that were not neurological.

Lets say everything started from my health, he said. I was suffering and feeling bad with myself, but I didnt know it was dysphoria: I didnt even know the word existed. It was Claudia who opened my mind. She said, Maybe something else is going on. And then, you know, gradually this thing happened that I found out I was a guy.

In a sense Mr. Beniamins experience resembles that of many trans people, who for reasons that may be societal, cultural, legal or psychological or all of those things combined are often forced to confront a constellation of challenges when reconciling the divergence between the gender assigned them and who they truly are. In his case there was an additional hurdle. Mr. Beniamin had always assumed that entering his fathers profession was impossible.

It is not that there are no female gondoliers, although thats how it was for 10 centuries. In 2010, Giorgia Boscolo became the first woman officially recognized by the Associazione Gondolieri di Venezia, or Venice Gondoliers Association. Now, of the 433 licensed gondoliers at work in Venice, five are women, according to Andrea Balbi, the president of the gondoliers association.

There is, in addition, Alex Hai, a German-Algerian transgender man who runs a private gondola service under the auspices of a hotel. Mr. Hai took the licensing test before transitioning to male in 2016, but did not pass it, Mr. Balbi said.

That test is open to all, Mr. Balbi insisted. Our job is for everyone male, female, transgender, maybe some other kind of gender we dont even know about, he said. Yet breaking into this signature profession is not so simple.

Nicolo Casarin, 37, was well established as a boat captain on the citys waterbus system when he finally passed the gondoliers test on his fourth try. I started when I was 19, and I got my license at 34, Mr. Casarin said. Its super-hard to get in, almost impossible if there is not someone in your family in the business.

The test, administered annually, entails much more than knowing how to master the art of balancing and rowing an asymmetrical 36-foot vessel through Venices 177 canals.

There are many hours of art history, histories of the city, navigation, routes, foreign languages to learn in addition to Italian and Venetian dialect, Mr. Casarin said. There is, too, boat maintenance and study of the tides and fickle winds along the Adriatic Sea.

Those things came easily enough to Mr. Beniamin, a byproduct of his upbringing around watercraft, a city kids easy familiarity with Venices six distinct districts, as well as a series of part-time high school gigs working as a tour guide. Although his comparatively small frame could be seen as an impediment to him as an oarsman, the toughest barrier he confronts as he begins training to enter the family business as the first openly transmasculine and licensed Venetian gondolier is also, in some ways, the least expected.

Since 2019, when he began hormone replacement therapy, Edoardo Beniamins outward appearance has increasingly conformed to conventional masculine ideals. Since December of last year, when he succeeded in petitioning the Italian bureaucracy to amend his birth certificate and other official documents to reflect his gender, he has been legally male.

What happened next, Mr. Beniamin said, is that, once I figured out I was a male, I also realized I had always had a certain idea of what masculinity is. I thought that to be a man is to be a certain way. Now what I think about is different. What I ask myself all the time is, What is a man?

In certain ways Venice is an ideal backdrop for his question. Insular, cryptic, ineffable in its appeal and yet riddled with clich, the labyrinthine city is intricately mapped and yet, as any visitor knows, confounding to navigate. Masculinity can also be like that.

Before I encountered Edoardo Beniamin, at the office of his speech therapist, Eleonora Magnelli, in Florence in January, I had given little thought to what bearing the sounds produced when air passes over my vocal cords had on my identity. I took for granted that I sounded like a cisgender man or, anyway, myself.

When Mr. Beniamin first contacted Ms. Magnelli, via Instagram, seeking information about a program to help transgender singers, his voice was, as she said, very metallic, and it bothered him. At the time there was little in the clinical literature about voice and gender stereotype. Many in her field assumed that taking testosterone and lowering vocal tones was sufficient to address the concerns of a transgender man.

But pitch is not the only parameter, Ms. Magnelli said. And the training we do differs from other kinds of speech therapy, because clinicians must always remember that clients are not affected by any pathology. We are just helping them in affirming their identity.

For Mr. Beniamin, the process of affirming himself through vocalization was as critical as some of the medical procedures underway to alter his physical appearance. You need to talk a lot if you want to be a gondolier, he said.

In fact, a gondoliers palaver and (less often these days) crooning is a large part of what tourists expect when they pay $85 for a half-hour of being rowed along a preset route in a velvet-upholstered craft. Changing my voice changed my life, Mr. Beniamin said.

It is not just that strangers no longer call him madam. (I dont just want a deeper voice at the end of this journey, he said.) Neither is it that Rambo, the Chihuahua he shares with fiance, now obeys his commands after years of ostentatiously ignoring him.

Obviously, its more than that, Mr. Beniamin said. What brings me euphoria is feeling people see me as I see me.

On an unseasonably warm January day in Florence, I accompanied Mr. Beniamin on a visit to Dr. Giulia Lo Russo, an aesthetic surgeon with a subspecialty in performing chest masculinization, or so-called top, surgery on transgender men. A video Dr. Lo Russo brought up on an iPad illustrated how broad the range of results can be. The point is not just to remove the breasts and reduce a female torso, Dr. Lo Russo said. You have to make a male torso.

Asked to explain the difference, Dr. Lo Russo spoke instead about her therapist. My psychologist asked me why I do these surgeries, she said. Why me? Im not L.G.B.T.Q. But I am deeply anti-conformist. I have had three children with three different men.

While we chatted, Mr. Beniamin casually prepared for his examination by stripping off a pullover sweater and T-shirt and unwinding the kinesiology tape he uses to bind his chest.

The state doesnt make it easy for people to get this surgery, Dr. Lo Russo continued. You have to wait one year for documents and, because of that, its hard to get on my schedule. I only do one top surgery a month, though with Edoardo, I put him on the roster a year in advance because it was clear to me that this was the right thing.

In the end, she added, as she held up a smartphone to snap before photos of her patient, people must be true to themselves.

For Sara Mion, 51, Mr. Beniamins mother, Edoardo is now her son the apprentice gondolier, a guy with a future wife and plans to start a family after marriage. If for a long while she was reluctant to accept her sons transition, she no longer has any such hesitation. As a mother, I decided, Do I lose her or do I try to understand him? she said.

Ms. Mion is a renal care nurse at a hospital in Venice and so it is somehow more poignant that the moment she accepted Edoardo as her son occurred when she administered one of his early testosterone injections. I told him then, I gave birth to you twice the first time in the hospital and now again with this, she said.

Ms. Mion and I were sitting in the sun near one of Venices many (opinions vary, but the overall consensus is there are about 450) footbridges. Gondoliers gossiped nearby in clusters, awaiting the tourists that uniquely in recent Venetian history were nowhere to be found.

Ms. Mion and Mr. Beniamins father, Paolo, divorced when their two children were young. Their relationship since then has remained cordial, if distant or as detached as any Venetian can hope to be in a city whose native population is small enough to see itself as endangered.

Paolo Beniamins gondola bobs in a prime berth along the Grand Canal, just outside the water gates of the luxurious Hotel Danieli. Ms. Mion said she finds it reassuring to know that, when the time comes for Edoardo to join in the family business, he can rely on his father as a cicerone.

Things were not always like that, as Edoardo Beniamin explained one day on a gondola piloted by Mr. Casarin. My dad tried to push the reality away for a long time, he said as Mr. Casarin propelled us through a series of especially narrow canals, or rii. He didnt want to use the pronouns, Mr. Beniamin said, referring to his preferred he and him. But then, the last time we talked, my dad said to call him when it was time for my top surgery and he would drive me to the hospital.

Venice that day was eerily tranquil, as at various times since the start of the pandemic, and this must also have been true during the great plague that permanently altered its history as a great world power. The lagoons bottle-green surface remained relatively placid as wavelets hit the gondolas glossy hull with lulling slaps.

Suddenly, a chevron of Italian Air Force jets blasted across the horizon toward the city, arcing through the sky above the St. Marks Square and the Doges Palace and leaving behind a trail of tricolor plumes. The mysterious aerial acrobatics continued for the next 20 minutes as jets zoomed in and out of view, the din from their turbines making it difficult to be heard.

Then, as abruptly as they had appeared, the aircraft tipped upward and vanished into the ether. That was when Mr. Beniamin noted how it seemed as if downdraft from the flyover had disturbed the waters surface, jostling the iron prows of vessels at mooring.

Gondolas are basically flat at the bottom, he said. Its an interesting thing to know about them, that it takes very little disturbance to rock the boat.

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Female athletes are as capable as male athletes | Opinion | kansan.com – The University Daily Kansan

Posted: April 19, 2022 at 2:07 am

The Kansas Senate passed a bill last month that would prevent transgender women from competing in girls sports in public schools from the elementary level to the state collegiate level. Kansas is the eighteenth state to propose a ban on transgender athletes competing in girls sports.

Labeled pro-girl and pro-women, proponents of the Kansas bill and similar bills claim that these actions protect female athletes.

However, I think this is one of the most covert misogynistic pieces of legislation ever written.

The bill, also called the Fairness in Womens Sports Act, requires teams to designate themselves as males, females or mixed, solely based on biological sex. The bill then explicitly states that sports designated for females, women or girls shall not be open to members of the male sex. If a person or organization sues on grounds of athletic opportunity deprivation and prevails on that claim, it is entitled to a broad remedy of monetary damages, including for any psychological, emotional and physical harm suffered, reasonable attorney fees and costs and any other appropriate relief.

Labeling transgender women and girls as members of the male sex is transphobic. Transgender folks are already at risk for discrimination because there are no laws in the state of Kansas that protect LGBTQ+ people from discrimination in housing, employment and public accommodations.

This bill would allow for schools to freely refuse to recognize students gender identity, who already experience higher rates of suicide, bullying and feelings of isolation at school.

School should be a safe place for all students. Recognizing students' differences especially those whose identities put them at riskis a key part of supporting students.

This legislation implies that there is no physical way that any woman born female could beat anyone born male in any sport under any circumstances. It continues the decades-long trend of underestimating female athletes by implying that they are fundamentally weaker.

The bill makes no express mention of people born female competing in male sports teams, only choosing to target those born male competing in women's and girls sports teams. Additionally, there has been almost no discourse around people born female competing in boys sports. Most of the bills passed focus solely on people born male competing in girls sports.

States such as Oklahoma, whose bill is titled the Save Womens Sports Act, Arkansas, Mississippi, Florida and other states only target transgender peoples participation in girls sports only with little to no mention of transgender participation in boys sports.

This is further indication that the ideas behind the bills are sexist and discredit female athletes. Legislators seem to have little to no concern for transgender males competing in boys sports further implying that legislators believe female athletes are inferior to male athletes.

Legislatures do not see people born female as threats to athletes born male because of traditionally sexist attitudes that state that women are weaker than men from the moment they are born.

This legislation also portrays people born male as predisposed athletic machines who would beat any woman simply because they have one X and one Y chromosome.

Saying this is offensive and simply untrue.

In reality, men and women have different strengths, such as women excelling more than men in endurance sports and men excelling in strength-related sports.

Further, Dr. Josha D. Safer, an endocrinologist at Mount Sinai Beth Israel with over 20 years of experience and the president of the U.S. Professional Association for Transgender Health, said it best: A persons genetic make-up and internal and external reproductive anatomy are not useful indicators of athletic performance and have not been used in elite competition for decades.

People born male are not automatically better at sports in the same way that people born female are not automatically better at cooking. Pushing these ideas just serves to reinforce offensive stereotypes.

Though the presence of testosterone can boost athletic performance, the differences in testosterone levels in males and females do not show up until after puberty.

Therefore, banning elementary-aged transgender women from competing in sports is unproductive and does not protect women (who, by the way, dont need your protection). It only serves to further alienate and bully children who are already among one of the highest-risk groups in the country.

Transgender youths are predisposed to experience higher levels of physical violence, sexual violence, discrimination and mental health struggles than their cisgender counterparts.

Other proponents of the bill have argued that transgender female athletes have a biological advantage after puberty due to the presence of testosterone in transgender women and that their athletic presence ensures that the playing field for cisgender women would not be equal.

However, 94% of transgender women have less than two nanomoles of testosterone per liter when on hormone replacement therapy, congruent with 95% of cisgender women having less than two nanomoles of testosterone per liter. So, where is the competitive advantage?

If legislatures really cared about female sportsmanship, I would encourage them to follow and engage with professional womens sports. Or I would encourage them to allocate more funding to women and girls in sports, to raise awareness for sexual assault and harassment in sports or invest in campaigns to encourage women and girls, cisgender and transgender, to get involved in sports. However, no legislatures have taken such action.

Their worry for womens sports is merely a facade for underlying sexism and transphobia.

These bills do not help women. Instead, they grossly alienate transgender children and belittle the work that female athletes put in nearly every day.

Allow transgender girls to have a childhood beyond discrimination and stop underestimating female athletes.

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Womb with a View: On the Science of Maternal Effects – lareviewofbooks

Posted: April 19, 2022 at 2:05 am

IN AN ARTICLE entitled How to Have the Best Pregnancy Ever, published in 2013 on the feminist news site Jezebel, Tracie Egan Morrissey offers advice to her readers. Doctors say that a glass of wine a day will not harm your unborn baby, or its IQ, she writes, referring to a study in the British Journal of Obstetrics and Gyncology. That being said, Morrissey continues, citing an article in PLOS ONE, even one glass of wine in your entire pregnancy could lower your babys IQ. What follows is a gleeful onslaught of contradictory and sometimes absurd guidance, much of it supported by peer-reviewed research. Dont eat fatty foods! Dont sleep on your back! Rub almond oil all over your taint! The drumbeat of directives and prohibitions will be familiar to any reader who has ever been pregnant. So might the ability of that drumbeat to keep the pregnant person on high alert. In 2022, it goes almost without saying that injunctions and warnings of this kind take aim at one party: the womb-bearing parent.

In a world where the CDC recommends that all women of childbearing age take birth control or abstain from drinking on the off chance that they might become pregnant, it may be difficult to imagine that the gestating parent wasnt always on the hook for the quality of the baby. To the contrary: Fathers, genetic chance, and the child-rearing environment each took a star turn. As historian and philosopher of science Sarah S. Richardson writes in The Maternal Imprint: The Contested Science of Maternal-Fetal Effects, the very idea that the parent contributing the egg plays an equal role in heredity to the parent contributing the sperm was radical, constituting something of a revolution on the scientific front and in ideas about gender. In the 1880s, German biologist August Weismann demonstrated that eggs and sperm contain equal quantities of hereditary material. He also showed that this material doesnt change as a result of its carriers life experiences. Before then, however, educated thinkers of all stripes believed that egg-bearers and sperm-bearers brought qualitatively and quantitatively different elements to shaping offspring. They also thought that what happened to prospective parents in the course of their lives could affect the hereditary material they passed to their offspring. According to Descartes, for example, mothers had nothing to do with a fetuss internal organs. Rather, they telegraphed through the umbilical cord what its body ought to look like. And either parent leading a dissipated life would, in the view of some 19th- and early 20th-century physicians, impart deficits to an embryo at conception. Physician and eugenicist Frederick Walker Mott railed especially at the race poisons, alcohol and syphilis, which could make sperm degenerate.

These ideas werent merely the result of technical constraints on what scientists could see and describe. Researchers enlisted evidence at the cellular level to support the story of separate reproductive roles for males and females. Biologists who observed sperm under a microscope concluded that the heroic, wriggling gametes rejuvenated eggs, infusing the lineage with vim and vigor. Even granting that eggs and sperm contributed the same amount of hereditary material, some researchers, like American zoologist William Keith Brooks, maintained that the egg carried instructions for a general species type what makes a fetus recognizable as, say, a human while the sperm contained the blueprint for a unique individual. Scottish biologists Patrick Geddes and J. Arthur Thomson took the division of labor further: ova were responsible for passive maintenance, they insisted, while sperm built and synthesized. Eggs, in effect, furnished raw material, while sperm served as both the architectural visionaries and the contractors realizing the vision. In all these accounts, whatever genius a child might possess is clearly derived from the male parent.

This is not to say that mothers were ever in the clear, particularly with respect to damaging a fetus. Even when Weismanns theory of sex equality in heredity was ascendant, many respected researchers, clinicians, and members of the public continued to understand the bodies of pregnant women as dangerously porous. Against this backdrop, the idea that women could influence their developing fetuses for good that the behaviors and attitudes of gestating parents could make children healthy, pious, and intelligent was hailed by some as progressive. Eugenic thinkers of a feminist bent and their followers seized on this possibility as creating an arena where women had agency. They used claims that women could gestate an improved race to argue that women should have the freedoms and resources to realize that potential.

If youre detecting a war of the sexes coursing through debates about how heredity works, youre not wrong. Gender politics, Richardson makes clear, at once spring from and are embedded in European and American theories of heredity. Late 19th- and early 20th-century thinkers wrote frankly about the premise that, on the cellular stage, the relationship between eggs and sperm played out the balance of power between the sexes. On the side of Weismann and the androgynous germ plasm, philosophical thinkers like Simone de Beauvoir cited equality in gametes as proof that the sexes themselves had to be equal in some fundamental way. Disciples of complementarity theories of egg and sperm, meanwhile, saw reflected under their microscopes the self-evident truth that males were active and original, igniting creation and driving innovation, while females were passive and inertial, warehousing nourishment and conserving traits through time.

Like other scientific theories, ideas about how parents influence their unborn children did not and do not emerge out of social vacuums. Richardson is the latest in a series of thinkers, including anthropologist Emily Martin, to identify how theories of heredity locate intuitions about causality in authoritative knowledge, however it might be defined in a particular time and place. That is to say, if an account feels true if so-called common sense suggests that it is true then it can be difficult for empirical evidence to dislodge the master narrative it is enlisted to support, whether with regard to the formation of a blastocyst or the readout from a PCR. The scientific and medical workers in Maternal Imprint were steeped in such master narratives. They appealed to and drew from the microscope and from the observations and lived experiences of everyday people. And their spheres of influence extended beyond the learned community and into Chautauqua tents, popular pamphlets, and amphitheaters, sometimes creating echo chambers in which popular belief and quantitative data reinforced one another.

Its well and good to call out logical fallacies and wishful interpretations of data in disciplines that have long since lost scientific legitimacy phrenology and eugenics, for instance. But the stakes are much higher when critics of science identify suspect master narratives at work in fields that are cutting-edge today. At the heart of Richardsons book is just such a critique of the burgeoning world of epigenetics. Epigenetics, the field of biology concerned with how DNA is expressed or silenced, has been welcomed as emancipating us from the tyranny of genetics our fate is no longer carved in stone in our genes and as a call to personal responsibility. As the CDC website on epigenetics puts it, Since your environment and behaviors, such as diet and exercise, can result in epigenetic changes, it is easy to see the connection between your genes and your behaviors and environment. Statements like these make the relationship between environment, behavior, and epigenetic change sound straightforward. Richardson takes on three prominent case studies in epigenetics to demonstrate that it is anything but.

Each case takes as its departure point a stressor a stimulus with the potential to knock a body out of biological equilibrium experienced by women of childbearing age. In two scenarios, the Dutch famine winter of 19441945 and the 1998 ice storm in the Montrgie region of Quebec, researchers focus on pregnancies that took place during or shortly after an acute challenge. They believe that gestating parents bodily experiences, like hunger and cold, and their psychological experiences, like anger and fear, leave epigenetic traces on the genomes of their children. The third case study, led by neurogeneticist Rachel Yehuda, seeks to explain through epigenetics how high cortisol levels in Holocaust survivors correlate with relatively low cortisol levels in their children. All three studies claim to have discovered an effect of the stressor on gene expression patterns in offspring. They also assert that these epigenetic changes cause deficits, including higher body mass indices among children gestated during the Dutch famine and the Quebecois ice storm and attenuated stress responses among the children of Holocaust survivors.

How big are these changes, and how worried should prospective parents be? (It would seem that our pregnant Jezebel readers now have epigenetics to add to the list of threats!)

Richardson points to major grounds for caution when interpreting the results of epigenetic studies. The first red flag is that the effects identified are subclinical, meaning that they wouldnt register at a doctors visit where a care provider is looking for signs that somethings wrong. Richardson refers to such effects as cryptic. By contrast, she notes, Previous eras of research [] focused on severe, gross prenatal deprivations causing visible, macroscopic outcomes. While research in the past was concerned with issues like folate deficiency causing spina bifida or thalidomide getting in the way of fetal limb formation, the biological traces of epigenetic difference arent at all obvious.

Setting aside health effects, the epigenetic changes measured in humans often fall well below the threshold of what scientists consider worth talking about in animal research. Studies of epigenetic changes in rats and mice show methylation levels, a metric of epigenetic change, between 20 and 100 percent at the locus of interest. Significant epigenetic changes like these do result in readily detectable changes in offspring bodies and behavior, whether it is in fur color or response to novel environments. Human studies, on the other hand, often report methylation differences under 10 percent.

The concerns pile on. Most researchers dont look at the entire epigenome, instead zeroing in on portions contained in pre-designed and commercially available chips, so the range of changes that might turn up in a study is limited from the outset. Epigenetic changes are measured in tissue, and it happens to matter what tissue you choose for measurement, since methylation patterns differ across the blood, skin, and internal organs within each person. Even a single tissue, like blood, contains many types of cells carrying information from all over the body. Their epigenetic signals might be responding to circumstances far removed from, say, a trauma experienced in utero. In fact, methylation patterns at some sites change on time scales ranging from hours to years. Not only is the tissue itself important, but it matters when in the life course you collect it if you dont get a sample at birth, its possible that the changes you observe took place at a later time and werent caused by experiences during gestation.

Then there are all the possible explanations for epigenetic differences that studies dont consider. Genes and epigenetics arent unrelated; your genes have a lot to say about your methylation patterns, so it may be that your biological family has more impact on your epigenetic profile than your lived experience. This is particularly noteworthy because studies focus almost exclusively on gestating parents, meaning that genetic, epigenetic, behavioral, and psychological data from the sperm-contributing parent are missing. And, as in all studies of variation, sample size matters. The smaller the data set, the more influence any single data point has on the story you tell.

People are invested in epigenetic narratives, just as they were invested in the self-evident truths of phrenology and the aspirational rallying cries of eugenics. And for good reason. Biological evidence, carrying with it deep forms of authority, confers legitimacy on experience: if its in the genes, it really happened. Recently, I described Richardsons doubts about the epigenetics of Holocaust survival to a colleague. He had heard Yehuda speak some years prior. His mother-in-law, he explained, was a Holocaust survivor, and the description Yehuda offered of the psychology of survivors mapped perfectly onto his own familys lived experience. The framework Yehuda proposed to explain the transmission of trauma across generations offered him and his wife a profound sense of relief; the anxiety his wife carried, and the anxiety they observed in their children, now felt inevitable and thus worthy of forgiveness. It had released them from the story that their suffering resulted from bad parenting. No thoughtful or rigorous critique, he told me, with a mix of gentle humor and deep seriousness, would persuade his family to relinquish the explanatory lifeline Yehuda had thrown to them.

In this anecdote, we find the crux of the issue: stories about heredity are maps of responsibility. They can function therapeutically or punitively, attributing problems to supposedly immutable sources like biology or to theoretically flexible causes like behavior. (Neither explanation, of course, is inherently progressive just ask LGBTQ-plus rights activists about the possibilities and perils of born this way.) What they often also do, as Richardson illustrates, is stick the gestating parent with the proverbial bill. No matter that the circumstances under investigation were out of pregnant peoples control: no gestating parent could be blamed for a famine in the middle of a war, an ice storm, or attempted genocide. The pathway of action for these catastrophes, according to scientists, is the maternal body. The gestating parent, therefore, becomes the locus of surveillance and intervention, the site of infinite possibility and infinite frustration in the quest for some elusively optimal way to be.

As an anthropologist who studies reproduction, I run in circles, biological and political, with colleagues about the role of the mother in reproductive outcomes. Entire professional organizations, including the International Society for the Developmental Origins of Health and Disease, convene on the premise that the gestating body or indeed, the potentially gestating body is the place to intercede to promote the birth of healthy children who grow into productive members of society. Here, I think we could benefit from turning back to the writer of the Jezebel article, Tracie Egan Morrissey, who has wisdom to offer on the question of how much any individual can steer reproductive destiny. Dont have asthma or allergies, she writes. Dont live near pollution. [] Dont be poor.

What would it mean for theories of heredity if we were to turn away from the individual as the site of intervention and focus instead on addressing human needs to eat, have safe shelter, and be free from persecution? What if we were to create a world in which gestating did not entail a nine-month passage through an environmental minefield? Then we might put what Richardson describes as the long reach of the womb in perspective and allow the womb-equipped among us a centuries-overdue sigh of relief.

Meredith Reiches is an associate professor of Anthropology at the University of Massachusetts, Boston.

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Womb with a View: On the Science of Maternal Effects - lareviewofbooks

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