Page 769«..1020..768769770771..780790..»

Joint Team from MIT and Synlogic Named a Biotechnology Grand Challenge Winner by Air Force Research Laboratory – PRNewswire

Posted: February 4, 2021 at 9:47 am

CAMBRIDGE, Mass., Feb. 2, 2021 /PRNewswire/ -- A collaboration between MIT Voigt Lab and Synlogic, Inc. (Nasdaq: SYBX), a clinical stage company bringing the transformative potential of synthetic biology to medicine, has been recognized by the Air Force Research Laboratory (AFRL) as a Biotechnology Grand Challenge Winner. One of four winning teams, the joint team comprised of MIT and Synlogic was awarded $1 million in an effort to spearhead innovation among small businesses in the field of biotechnology for the Department of Defense.

"We are honored to be recognized by the AFRL and are thrilled to collaborate with Synlogic to achieve this success," said Christopher Voigt, MIT Professor of Biological Engineering and Principal Investigator for the MIT Voigt Lab. "Our challenge was determining which organization would possess the proven expertise in both the development and manufacturing of novel biotherapeutic products, and we couldn't be happier that we have found that partner in Synlogic."

Christopher Voigt is an expert in synthetic biology and biotechnology with extensive research programs in defense, chemistry/materials, and agriculture. The focus of the Voigt Lab is to develop new experimental and theoretical methods to push the scale of genetic engineering, with the ultimate objective of genome design. This will impact the engineering of biology for a broad range of applications, including agriculture, materials, chemicals, and medicine. Professor Voigt's research spans applications for the Army, Navy, and Air Force, and he works closely with scientists across the service labs as well as hosting DoD researchers at MIT.

"Our internal and fully integrated Process Development & Manufacturing Sciences organization has demonstrated leading technical expertise in the field of Synthetic Biotic medicines and we look forward to applying innovative solutions for today's real-life challenges," said Antoine Awad, Synlogic's Chief Operating Officer."As we develop our internal pipeline we are excited to leverage our core capabilities to advance innovative partner projects, such as applying our bioprocess and manufacturing to advance the goals of the AFRL."

Together, Synlogic and the Voigt Lab will collaborate to generate and manufacture engineered strains by performing an assessment of process manufacturability, with optimization performed to maximize high cell density growth and high end of fermentation (EOF) viability. The goal of this work is to produce a live bacterial therapeutic that would improve pilot performance and decision-making when battling fatigue during long missions.

Learn more about Synlogic at http://www.synlogictx.com.

About Synlogic

Synlogic is bringing the transformative potential of synthetic biology to medicine. With a premiere synthetic biology platform that leverages a reproducible, modular approach to microbial engineering, Synlogic designs Synthetic Biotic medicines that target validated underlying biology to treat disease in new ways. Synlogic's proprietary pipeline includes Synthetic Biotic medicines for the treatment of metabolic disorders including Phenylketonuria (PKU) and Enteric Hyperoxaluria (HOX). The company is also building a portfolio of partner-able assets in immunology and oncology.

Forward-Looking Statements

This press release contains "forward-looking statements" that involve substantial risks and uncertainties for purposes of the safe harbor provided by the Private Securities Litigation Reform Act of 1995. All statements, other than statements of historical facts, included in this press release regarding strategy, future operations, clinical development plans, future financial position, future revenue, projected expenses, prospects, plans and objectives of management are forward-looking statements. In addition, when or if used in this press release, the words "may," "could," "should," "anticipate," "believe," "estimate," "expect," "intend," "plan," "predict" and similar expressions and their variants, as they relate to Synlogic may identify forward-looking statements. Examples of forward-looking statements, include, but are not limited to, statements regarding the potential of Synlogic's platform to develop therapeutics to address a wide range of diseases including: cancer, inborn errors of metabolism, and inflammatory and immune disorders; the future clinical development of Synthetic Biotic medicines; the approach Synlogic is taking to discover and develop novel therapeutics using synthetic biology; and the expected timing of Synlogic's clinical trials including the Phase 1 study for SYNB1891 and SYNB8802 and the Phase 2 study of SYNB1618, and availability of clinical trial data from that study and other studies.

Actual results could differ materially from those contained in any forward-looking statement as a result of various factors, including: the uncertainties inherent in the clinical and preclinical development process; the ability ofSynlogicto protect its intellectual property rights; and legislative, regulatory, political and economic developments, as well as those risks identified under the heading "Risk Factors" inSynlogic'sfilings with theSEC. The forward-looking statements contained in this press release reflectSynlogic'scurrent views with respect to future events.Synlogicanticipates that subsequent events and developments will cause its views to change. However, whileSynlogicmay elect to update these forward-looking statements in the future,Synlogicspecifically disclaims any obligation to do so. These forward-looking statements should not be relied upon as representing Synlogic's view as of any date subsequent to the date hereof.

SOURCE Synlogic, Inc.

Home

View original post here:
Joint Team from MIT and Synlogic Named a Biotechnology Grand Challenge Winner by Air Force Research Laboratory - PRNewswire

Posted in Genetic Engineering | Comments Off on Joint Team from MIT and Synlogic Named a Biotechnology Grand Challenge Winner by Air Force Research Laboratory – PRNewswire

Uncertain future: Will Europe’s Green Deal encourage or cripple crop gene-editing innovation? – Genetic Literacy Project

Posted: February 4, 2021 at 9:47 am

The EU Green Deal and its Farm-to-Fork and Biodiversity Strategies stipulate ambitious policy objectives that will fundamentally impact agricultural businesses and value chains. Are these objectives realistic? And how do they fit with the EUs policies on food security, the internal market, international trade and multilateral economic agreements? As significant conflicts of goals become apparent, the discussion on expectations, preconditions and consequences is now underway.

The Farm to Fork Strategy concretely foresees a reduction of pesticide and fertilizer use of 50% and 20% by 2030, respectively. In addition, 25% of EUs agricultural land is supposed to be put under organic farming conditions, which generally means a reduction in productivity. Unfortunately, the strategy is less concrete about the important role of innovation in general and plant breeding innovation specifically to compensate for productivity losses and to contribute to a more sustainable agriculture.

On July 25, 2018 the European Court of Justice (ECJ) published its ruling on mutagenesis breeding, including targeted genome editing techniques. This ruling subjected new tools like CRISPR Cas-9 to the EUs strict rules and requirements for GMOs, and with that effectively prohibited European plant breeders and farmers from utilizing these powerful technologies. These regulatory obstacles are not based on evidence showing that genome editing poses a risk to human health or the environment, but rather on political interference in the regulatory approval process. The COVID pandemic made this abundantly clear. In July 2020, for example, the EU suspended some of its excessive genetic engineering rules to facilitate the development of COVID vaccines, and has since celebrated the approval of these important drugs while trying to prevent the use of biotechnology in agriculture.

Since the discovery of the laws of genetics by Gregory Mendel in 1866, plant breeders have continuously integrated the latest plant biology innovations into their toolbox to develop enhanced crops that help farmers sustainably grow the food we all depend on.

Europes seed sector, technology developers and public researchers have always been important actors in this evolving effort and remain global leaders in developing improved plant breeding methods. They work tirelessly to provide farmers with crop varieties that fit the needs of a highly productive and sustainable agriculture system and meet the exacting demands of consumers. It is no secret that these experts understand the value of new breeding techniques (NBTs) like CRISPR and want to employ them.

Contrary to the claim of some environmental groups that genome editing provides new avenues of control through modifying specific plant traits, most notably insect and herbicide resistance, industrial applications of this sort are only one aspect of NBT research, and a minor one at that. Our recent survey of 62 private plant breeding companies, 90% of which are small and medium size firms (SMEs), confirms that EU plant breeders are able and willing to use these technologies to develop a wide range of crop species and traits for farmers. From grape vine to wheat, NBTs can generate innovation to protect Europes traditional crops from pests and diseases and other threats posed by climate change.

Independent of their size, many companies are already using NBTs in their R&D pipelines for technology development, gene discovery and to produce improved plant varieties. These activities cover a wide range of agricultural and horticultural cropsfrom the so-called cash crops like maize and soybean to minor crops like pulses, forage crops and chicoryand span a wide diversity of characteristics, including yield, plant architecture, disease and pest resistance, food-quality traits and abiotic stresses like drought and heat.

See the article here:
Uncertain future: Will Europe's Green Deal encourage or cripple crop gene-editing innovation? - Genetic Literacy Project

Posted in Genetic Engineering | Comments Off on Uncertain future: Will Europe’s Green Deal encourage or cripple crop gene-editing innovation? – Genetic Literacy Project

Bayer’s ThryvOn Technology Moves Forward – Southeast AgNet

Posted: February 4, 2021 at 9:47 am

The U.S. Department of Agricultures (USDA) Animal and Plant Health Inspection Service (APHIS) recently announced the deregulation of a cotton variety, designated as MON 88702, otherwise known as ThryvOn Technology. It was developed by the Monsanto Company, which is now owned by Bayer. It uses genetic engineering for resistance to certain insects, primarily tarnished plant bugs.

APHIS considered all public comments and conducted a thorough review of the potential environmental impacts in its final EA pursuant to the National Environmental Policy Act (NEPA), reaching a finding of no significant impact. They concluded the MON 88702 cotton variety is unlikely to pose a plant pest risk to agricultural crops or other plants in the U.S. and deregulated it, effective Jan. 19, 2021.

Bayers ThryvOn Technology represents the industrys first cotton biotech trait to protect against feeding damage from key tarnished plant bug and thrips species. These include tobacco thrips, Western flower thrips, tarnished plant bug and the Western Tarnished Plant bug. The technology provides cotton growers an additional tool to manage these damaging pests.

Related

Read more from the original source:
Bayer's ThryvOn Technology Moves Forward - Southeast AgNet

Posted in Genetic Engineering | Comments Off on Bayer’s ThryvOn Technology Moves Forward – Southeast AgNet

FL Doctors Make Breakthrough Using Stem Cells to Treat …

Posted: February 2, 2021 at 11:53 pm

According to a report from CBS4, doctors in South Florida say an experimental treatment involving stem cells has been successful in treating severe cases of COVID.

The study, which took place at Jackson Memorial Hospital and the University Miami Tower, involved many patients with acute respiratory distress syndrome (ARDS). The groundbreaking treatment, using stem cells from a babys umbilical cord, was shown to safely reduce the risk of death and increase the speed of recovery time faster for some of the studys most ill patients. The FDA approved the trial.

In a double-blind study involving 24 patients with ARDS, each was administered two infusions, given days apart of either the stem cells or a placebo. Researchers discovered that the patient survival rate treated with the stem cells was 91 percent.

Dr. Camillo Ricordi, director of the Cell Transplant Center at the University of Miami Miller School of Medicine, said these stem cells have potential to restore normal immune response and promote tissue regeneration.

When a person develops ARDS, their lungs develop severe inflammation and buildup fluid in their lungs.

Ricordi also said the ARDS patients usually undergo invasive procedures, but that was not the case with this procedure.

Link:
FL Doctors Make Breakthrough Using Stem Cells to Treat ...

Posted in Florida Stem Cells | Comments Off on FL Doctors Make Breakthrough Using Stem Cells to Treat …

This Guy Injected His Dick With Stem Cells to Try to Make …

Posted: February 2, 2021 at 11:53 pm

Ben Greenfield is a cult figure among fitness fanatics, a guru to the sort of nerds who devote themselves to meticulously monitoring their own biometric data for insight into their personal health. He has more than 50,000 Twitter followers, 60,000 Facebook fans, and 30,000 YouTube subscribes. Now he may become known for something else entirely: Injecting himself with stem cells in hopes that it will make his dick bigger.

I want to take care of my body in the best way possible, Greenfield said during a webinar earlier this month, in which he spoke to listeners while walking on a treadmill. Part of that, he said, means having fun with using what science has given us to make the body better.

Greenfield is something of a human science experiment, whos willing to try almost anything in the name of getting ripped and some publicity. He has subjected himself to platelet-rich plasma injections, stem cell injections, and even sound wave therapy, all in search of bodily enhancement and better health.

I live my life as an N=1, he told Gizmodo, referencing research studies with just one subject.

In November, Greenfield visited U.S. Stem Cell, a controversial clinic in Florida, to have his penis injected with his own stem cells. If the name of the clinic seems familiar, thats because its the same Florida clinic that last year unintentionally blinded three patients in a clinical trial of an unproven stem cell therapy. In August 2017, the Food and Drug Administration sent U.S. Stem Cell and its chief scientific officer Kristin Comella (who appears in the webinar video with Greenfield) a warning letter for marketing stem cell products without FDA approval and for significant deviations from current good manufacturing practice requirements, including some that could impact the sterility of their products, putting patients at risk. U.S. Stem Cell Clinic, the FDA said, even tried to interfere the FDAs investigation by denying agency employees access to facilities. (U.S. Stem Cell did not respond to repeated requests for comment.)

I wanted to go from good to great, and to get a bigger dick, he told Gizmodo. Im not going to lie, thats why guys without erectile dysfunction would do this.

In the webinar, Greenfield and Comella explain how the procedure worked. Greenfield had U.S. Stem Cell isolate stem cells from his bodys fat cells. Then, said Greenfield, those stem cells were injected into the meat of the tissue of his penis. (You dont feel a thing other than a little bit of pressure, he said in the webinar.)

Several early-stage studies have shown that stem cells do show promise in treating erectile dysfunction in men. A press release from U.S. Stem Cell cites one such study from 2016, in which adipose-derived stem cells were used to treat 17 men who suffered from erectile dysfunction after undergoing a radical prostatectomy for prostate cancer. The stem cells were injected at the base of their penis. The men experienced limited side effects, and eight of the 17 men were able to successfully get erections and have sex again. Greenfield, though, was seeking to enhance his manhood, rather than to fix any medical problem. The evidence that such a treatment could help treat erectile troubles is still nascent. Evidence that it could enhance a man without any such issues is even more tenuous.

Kiki Sanford, a molecular physiologist and host of The Stem Cell Podcast, told Gizmodo that while the study cited in the press release suggests the injections might not be harmful, it was also too small of a study to really indicate whether they might actually work, even in men with erectile issues.

You cant say that since a study might have enhanced function in deficient tissue it will do the same in normal tissue, Sanford said. The body doesnt necessarily work that way.

And, she said, even if the procedure is safe there is still risk of complications like infectionall for a procedure that has little chance of working.

Nonetheless, Greenfield said in the webinar that the procedure had made him noticeably better hung.

Three or four days after the procedure, he said, it was almost like it grew. His erections were also bigger, his penis got harder, and his orgasms were better, he said. The better orgasms, he said, might be a placebo effect, but the anatomical changes in size cannot be denied.

Gizmodo asked Greenfield whether he had measured his change in size.

I havent taken out a ruler, he said, explaining that he felt the size fluctuates too much to get a consistent measurement. But he thinks it looks noticeably larger.

When inside of my wife, she can tell, he added.

Greenfield, who considers himself a biohacker, is a big believer in stem cells. Hes had them in his knee and hip to help him recover from an injury, which he said was successful. Hes also injected them into his own arm as a performance enhancer at home. With the help of stem cells, he said, by the time he is 40 in a few years, he hopes to have attained a biological age of 25.

He told Gizmodo that he thoroughly researches any new therapy he plans to undertake, and he felt confident that this one was safe.

There is still a risk, he said. But the payoff in terms of health is very big. You cant always wait for things to be thoroughly studied.

Stem cells do have lots of therapeutic promise. But while most of those treatments are still little more than theoretical, clinics offering stem cell procedures have flourished because FDA regulations allow clinics to inject patients with their own stem cells as long as those cells meet criteria including minimal manipulation and are intended to just perform their normal function. Some treatments, including some of those offered by U.S. Stem Cell, seem to flout those rules, but so far the FDA has had difficulty cracking down. That may change, with a new regulatory initiative announced last fall.

Several US clinics market better sex through stem cell injections to both men and women, for price tags that run more than $1,000.

Stem cell therapies are all very exciting for their potential to help people, but very few have been shown to work well enough in clinical trials to gain FDA approval, said Sanford. We are still very much in the age of snake-oil with respect to many of the therapies that are being marketed, which is too bad because the potential is there.

But why would Greenfield, a fitness guru who says he has no problems with getting it up, want to try a risky, unproven procedure on himself?

Its not normal, he said in the webinar. I dont think ancient man injected stem cells, especially into his nether region.

Then he rattled off a laundry list of modern assailants, including cellphones, and a list of problems including autism and erectile dysfunction that he believes may be related.

Were fighting an uphill battle, he said.

Injecting his penis with stem cells, he continued, is just one way to combat the perils of modern life.

Update, 3:35 p.m., May 5, 2020: This post has been updated to remove a broken video embed.

See the rest here:
This Guy Injected His Dick With Stem Cells to Try to Make ...

Posted in Florida Stem Cells | Comments Off on This Guy Injected His Dick With Stem Cells to Try to Make …

10 Best Stem Cell Beauty Products On The Market Today

Posted: February 2, 2021 at 11:53 pm

Fight the signs of premature aging with these stem cell skin care beauty products. A lot of companies claim to incorporate the benefits of plant and human stem cells, as well as components secreted by them, into the best stem cell beauty products on the market.

Below, we present what appears (based on company claims) to be ten of the best products available today.

As a publisher of stem cell news, we havent traditionally wandered into the world of claims made by stem cell beauty products suppliers. For obvious reasons, we cannot guarantee the accuracy of the claims made by these companies or the presence of specific active agents within them.

However, we get approached daily with questions about this topic and know that people are seeking information about it from a source that: 1) Doesnt inflate the claims, and 2) Understands the science.

For this reason, we have decided to share with you what appear to be interesting skin care options, coupled with a healthy dose of warnings reminding you that the stated claims may or may not be accurate.

Kimera Labs makes the top of this list for numerous reasons. First, the companys science it is solid. Instead of being a supplier of beauty products, the company is a specialty contract research organization (CRO) focusing on regenerative medicine applications, including exosome purification. Exosomes are small vesicles (~30-100nm) that are secreted by nearly all cell types and act as intracellular mail.

Exosomes transfer DNA, RNA, and proteins to other cells, thereby altering the function of the other cells.

Second, the company has an FDA registered tissue facility in Miami, FL, where it develops pharmaceutical grade, exosome-based regenerative therapies. The company has a 6,000 sq. ft. facility in Miramar, Florida, that includes impressive features such asISO:9001/13485 certification, cleanrooms, and a variety of high-end scientific equipment.

Third, the company is run by Dr. Duncan Ross, a highly regarded scientist with a Ph.D. in Immunology from the University of Miami. Dr. Ross is also a Principal at The Kimera Society, a non-profit organization dedicated to the advancementof stem cells, regenerative medicine,and cancer immunotherapies.

For those seeking stem cell beauty products, the companys core offering is XoGlo, a product which provides growth and healing signals to guide the re-deposition of tissue and avoid the scarring that often accompanies burns or other skin damage. You can see an incredible Case Study from the company in which XoGlo was used to heal second-degree burns in a patient in approximately seven days. The product can also be used for general skin health and enhancement.

More information on the XoGlois available here.

According to the company, this facial cleanser is formulated with stem cytokines that promote the skins ability to heal itself, leaving softer and smoother skin. It also has essential fatty acids, detoxifying actives, antioxidants, and anti-inflammatory botanicals that deeply cleanse your skin of excess oil, impurities, and surface debris. This makes the skin smoother, more balanced, and hydrated.

Lifeline says that it offers a moisture serum with a formula consisting of proteins and peptides from pluripotent stem cells. It works by reversing skin aging signs and actively moisturizing the skin with its cucumber melon extracts. The serum primarily targets the reduction of wrinkles and fine lines.

At $105 for a 1 oz bottle, it is notable that the company does not mention how it sources pluripotent stem cells, leaving key questions about its active ingredients unanswered.

Heres another skin care serum on this list of stem cellbeauty products. This serum is enriched with a tissue nutrient solution (TNS) technology that reduces wrinkles and fine lines and improves skin texture and tone. TNS is formulated with matrix proteins, cytokines, soluble collagen, antioxidants, and growth factors that are essential to keeping skin healthy.

This regenerative eye creamcontains autokine-CM obtained from adult stem cells through mini-liposuction. This unique ingredient is composed of extracted cytokines, matrix proteins, and growth factors from adult stem cells that help improve the skins ability to heal. It also aids in synthesizing elastin and collagen production, thus reducing fine lines and wrinkles, improving skin tone and texture, and increasing epidermal thickness in the eye area.

Venus Skin introduced a stem cell therapy serum packed with bio-signals from bone marrow mesenchymal stem cells for stimulation of skin tissue repair and healing. This reverses aging signs and rejuvenates the feel and look of the skin. It also contains essential vitamins A, C, and E to normalize skin functions, promote collagen synthesis in the skin, and reduce the appearance of scars, respectively.

This hydrating mask possesses a stem cell culture technology that penetrates deep into the skin for intense and long-lasting hydration. This leaves the skin well-moisturized and supple. It also fills fine lines and wrinkles and restores parched skin, bringing skin moisture and smoothness back.

This intensive facial mist restores the skins elasticity and moisture with its fine liquid particles that immediately penetrate the skin. It contains APL stem cell-conditioned medium extracts that help regenerate, whiten, and hydrate the skin and minimize pores and wrinkles. The facial mist also has chamomile extracts that bring a soothing effect to the skin.

Skin Drink Phytoceuticals highlights three potent anti-aging skin care ingredients in this serum.PhytoCellTec is an ingredient that safeguards the skin stem cells longevity, fights off skin aging, and delays biological aging of cells. Derm SRC works on reducing wrinkles and fine lines, while Ellagi-C promotes skin elasticity and suppleness.

This snail serum boasts an epidermal growth factor ingredient that stimulates the skins stem cell growth and cell survival. It also has a snail mucus extract that refreshes and brightens the skin. Aside from that, the serum contains other natural ingredients, such as macadamia seed oil and hydrolyzed placenta extract, for skin hydration and nourishment.

Which of these components actually enhance skin health and complexion? Hard to say, but the ingredient list certainly is exotic.

With this list of the best beauty products, it can be tricky to know which ones will enhance skin health. Stem cells are becoming a common ingredient in skin products, but regulation of this area is sparse, making it important to be vigilant in your selection.

A steep price tag doesnt guarantee results. Claims of active ingredients do not guarantee they are present. Even the confirmed presence of an ingredient by third-party testing does not substantiate its claimed effect.

However, there are hundreds of user reviews for some of these products, so the possibility for these skin care products to improve the appearance of your skin does exist. Importantly, many of these stem cell beauty products contain an impressive range of other ingredients, so you could benefit from them due to effects unrelated to the claimed stem cell components.

When judging the efficacy of these products, the only clear answer is that you need to be your own study of one.

Let this infographic be your guide. Download it now and use it as a reference later.

If you found this article valuable, subscribe to BioInformantsstem cell industry updates.We are the industry leaders in stem cell research, with research cited byThe Wall Street Journal, Xconomy, AABB, andVogue Magazine.Bringing you breaking news on an ongoing basis, join nearly aa million loyal readers, including physicians, scientists, executives, investors, and philanthropists.

Do you have questions about whether a stem cell treatment could address your medical condition?

As the worlds largest publisher of stem cell industry news, we understandably cannot provide clinical treatments or advice. However, GIOSTAR can provide you with medical guidance and advice. In alignment with what we believe at BioInformant, it offers cutting-edge, extensively researched stem cell therapy options.

Click here toSchedule a Consultationor ask GIOSTAR your questions.

More here:
10 Best Stem Cell Beauty Products On The Market Today

Posted in Florida Stem Cells | Comments Off on 10 Best Stem Cell Beauty Products On The Market Today

HealthLynked’s The Future of Healthcare Summit Brings Healthcare Experts and Technology Innovators from Around the World to Naples, Florida -…

Posted: February 2, 2021 at 11:53 pm

NAPLES, Fla., Jan. 29, 2021 /PRNewswire/ -- HealthLynked Corp. (OTCQB: HLYK), a global healthcare network focused on care management of its members and a provider of healthcare technologies that connects doctors, patients and medical data, today announced that it will host the first annual Future of Healthcare Summit that will convene the top leaders in the $5 trillion healthcare industry at Arthrex's corporate campus that features a 30,000-SF fitness center and 200,000-SF Innovation Hotelin Naples, Florida from March 15-17th.

The summit is an invitation only event for healthcare providers. The event features world-class CEOs, innovators and industry experts who will come together to present a series of lectures on a wide range of healthcare topics and explore what can be done to both catalyze innovation and improve healthcare.

Dr. Michael Dent, HealthLynked's CEO has developed an agenda that focuses on genomics, functional medicine, anti-aging, stem cells, artificial intelligence, diagnostic advances, telemedicine, intellectual property, tissue regeneration, cancer treatments and medical devices.

The summit venue will be open to the public on Tuesday, March 16th, where a series of Ted Talk style lectures will cover the latest healthcare trends, technology, and treatments. This open forum will allow the public the opportunity to learn about the latest advances in healthcare and how they are being applied today and what to expect in future.

HealthLynked has confirmed a world-class slate of speakers including:

Attendees of the summit include doctors, hospital executives, academics, researchers, venture capitalists, pharmaceutical firms, policymakers, philanthropists, and future leaders. The seating for the summit will follow COVID-19 spacing guidelines and Arthrex campus facilities are equipped with Synexisair purification systems that kill airborne COVID-19 to add an additional layer of safety for the attendees.

For a look at the full agenda, as well as speaker bios, please visit the 2021 Healthcare Summitwebsite. For additional sponsorship opportunities please email [emailprotected].

Dr. Michael Dent, Chief Executive Officer of HealthLynked stated, "The next 15 years will bring a wave of medical breakthroughs in new therapies, medicines, medical devices and data analytics. We have achieved new milestones in gene editing, cancer immunotherapy and artificial intelligence. All of these advances will allow us to more effectively treat disease and find cures that have eluded us. Our goal is to provide an informative series of lectures to show the future of healthcare and create an environment for innovate thought leaders to turn ideas into actionable solutions."

About HealthLynked Corp.

HealthLynked Corp. provides a solution for both patient members and providers to improve healthcare through the efficient exchange of medical information. The HealthLynked Network is a cloud-based platform that allows members to connect with their healthcare providers and take more control of their healthcare. Members enter their medical information, including medications, allergies, past surgeries and personal health records, in one convenient online and secure location, free of charge. Participating healthcare providers can connect with their current and future patients through the system. Benefits to in-network providers include the ability to utilize the HealthLynked patent pending patient access hub "PAH" for patient analytics. Other benefits for preferred providers include HLYK marketing tools to connect with their active and inactive patients to improve patient retention, access more accurate and current patient information, provide more efficient online scheduling and to fill last minute cancelations using the Company's "real time appointment scheduling" all within its mobile application. Preferred providers pay a monthly fee to access these HealthLynked services. For additional information about HealthLynked Corp., please visit http://www.healthlynked.com and connect with HealthLynked on Twitter, Facebook, and LinkedIn.

Forward Looking Statements

Forward-Looking Statements in this press release, which are not historical facts, are forward-looking statements within the meaning of the Private Securities Litigation Reform Act of 1995. Our actual results, including as a result of any acquisitions, performance or achievements may differ materially from those expressed or implied by these forward-looking statements. In some cases, you can identify forward-looking statements by the use of words such as "may," "could," "expect," "intend," "plan," "seek," "anticipate," "believe," "estimate," "predict," "potential," "continue," "likely," "will," "would" and variations of these terms and similar expressions, or the negative of these terms or similar expressions. Such forward-looking statements are necessarily based upon estimates and assumptions that, while considered reasonable by our management, and us are inherently uncertain. We caution you not to place undue reliance on any forward-looking statements, which are made as of the date of this press release. We undertake no obligation to update publicly any of these forward-looking statements to reflect actual results, new information or future events, changes in assumptions or changes in other factors affecting forward looking statements, except to the extent required by applicable laws. If we update one or more forward-looking statements, no inference should be drawn that we will make additional updates with respect to those or other forward-looking statements. Certain risks and uncertainties applicable to our operations and us are described in the "Risk Factors" section of our most recent Annual Report on Form 10-K and in other filings we have made with the U.S. Securities and Exchange Commission. These reports are publicly available at http://www.sec.gov.

Contacts:

George O'Leary Chief Financial Officer [emailprotected] (800) 928-7144, ext. 103

Investor Relations Contacts:

Jim HockHanover International Inc.[emailprotected]760-564-7400

SOURCE HealthLynked Corp.

Continue reading here:
HealthLynked's The Future of Healthcare Summit Brings Healthcare Experts and Technology Innovators from Around the World to Naples, Florida -...

Posted in Florida Stem Cells | Comments Off on HealthLynked’s The Future of Healthcare Summit Brings Healthcare Experts and Technology Innovators from Around the World to Naples, Florida -…

Meeting the commercialization challenge of a surging gene and cell therapy market – FierceBiotech

Posted: February 2, 2021 at 11:50 pm

Undaunted by the challenges the COVID-19 pandemic unleashed on the world the expected surge of cell and gene therapies already in the pipeline and on the horizon will continue to materialize, and with them the complexity of riding that wave of innovation.

Just two years ago the U.S. Food and Drug Administration (FDA) forecast that it would be flooded by 2020 with about 200 Investigational New Drugs a year on top of the more than 800 active cell-based or gene therapies it was already processing. The agency projected that by 2025 it would be approving anywhere between 10 to 20 new cell and gene therapy products a year. By 2024, the FDA and the pharmaceutical and biopharmaceutical industries expect more than 40 new and innovative cell and gene therapies will be available on the market.

Although the pandemic disrupted drug discovery and development efforts early in the crisis, the industry has been quick to respond and adjust. The CG&T market will likely slow from $6.68 billion in 2019 to $6.92 in 2020 because of the pandemic, yet it is forecast to recover and grow to an estimated $13.23 billion by 2023, according to Researchandmarkets.com.

There is more momentum than ever before to bring these innovative medicines to market, said Doug Cook, president of Commercialization Services and Animal Health at AmerisourceBergen. The influx of therapies offers tremendous promise and hope to patients with conditions where there are few treatment options and no cures. But these complex products introduce new considerations throughout the commercialization journey, so its critical that manufacturers work with a partner that can help them navigate challenges at each stepfrom pre-clinical and commercial logistics to market access strategies and patient support solutions.

Because CG&T are derived from a patients own cells, time and temperature have become critical factors from the moment they are extracted on through the manufacturing process and then returned as a curative life-saving therapy. As such, there is little room for failure or delay throughout the supply chain.

Given the narrow window of viability of these therapies they need to be shipped as quickly as possible to preserve the time the cells are active. With such a constraint on the time those cells are viable, the pressure on logistics providers has become even more acute. Clearly, supply chain companies that have larger networks and better access to more depots are more advantageous for manufacturers, but more importantly, for patients.

The complexity of these treatments can be staggering both from a development perspective and on into storage and transportation, Cook said. For the first time, the patient is now part of the supply chain where they used to be at the end of it, and thats really different than anything weve seen before.

Many, if not most, of CG&T require ultra-frozen storage from the development stage on through to the application to the patient. This is an element of the supply chain the public is becoming acutely aware of as a result of the COVID-19 pandemic. For example: Pfizer-BioNTechs COVID-19 vaccine must be stored in containers that can achieve between -80 to -60 degrees Celsius. C> require storage conditions from ultracold (-80 degrees Celsius) down to cryogenic temperatures (-135 to -150 degrees Celsius). To ensure the product remains viable throughout transport, the shipping containers must have the ability to keep a constant monitor of the temperatures as well as have real-time GPS tracking.

The shorter the shelf life of the cell therapy, the more intense the logistical challenges. To achieve successful outcomes in what are very patient-centric treatmentsoften referred to as a vein-to-vein supply chainrequires manufacturers to partner with experienced and technologically advanced wholesalers and distributors that have a global reach and ability to address issues with customs and country-specific regulatory requirements.

As the wave of these therapies begins to swell past the approval stage, the need for infrastructure that can handle CG&T has to be in place to avoid bottlenecks and delays that could limit patient access.

Because of all the complexity, handoffs are where mistakes happen, and you need a partner who focuses on all those small details and makes the process seamless, Cook said. This is where experience matters, and capabilities are essential.

In order to continue to meet and exceed its capabilities, early last year AmerisourceBergen strengthened its logistics offerings by integrating its global logistics provider, World Courier, with ICS, its third-party (3PL) provider. Now fully integrated, the service offers a complete cryogenic supply chain. World Courier and ICS offer vapor-charged cryogenic storage with fully automated technology and temperature-controlled transport from a manufacturers location to a storage facility and then to each point of care in dry shipment containers. The group has extensive experience in navigating international borders while maintaining temperature requirements.

With a global network of more than 140 offices, World Couriers has the ability to provide cryogenic shipping solutions that are close to patient and manufacturing locations, which provides much more flexibility as well as cutting response times for patient and hospital needs.

Its become clear as we navigated through COVID that everything has to be connected in ways they werent before, Cook said. As a result, weve invested in more technology services to better position ourselves to support CG&T and play the role of partner and connector more than ever before.

And we are always looking at ways to offer more cohesive capabilities.

To learn more about how AmerisourceBergen anticipates supply and demand and how we do business and the role of distributors in the supply chain check out:https://www.amerisourcebergen.com/pharmaceutical-distribution/value-of-the-distributor

Visit link:
Meeting the commercialization challenge of a surging gene and cell therapy market - FierceBiotech

Posted in Cell Therapy | Comments Off on Meeting the commercialization challenge of a surging gene and cell therapy market – FierceBiotech

Missouri State Representative Indicted Over Alleged Stem Cell Therapy Scam – IFLScience

Posted: February 2, 2021 at 11:50 pm

Tricia Derges, a member of the Missouri House of Representatives and doctor, has been indicted by a grand jury for among other things allegedly injecting people with amniotic fluid and telling them mesenchymal stem cells made it a miracle cure. Derges has pled not guilty, and IFLScience cannot assess the accuracy of the charges. However, the case brings attention to growing use of unproven and dangerous stem cell treatments.

The case against Derges is being taken by Tim Garrison, the U.S. Attorney for Missouri's Western District. Garrison alleges Derges acquired stem cell-free amniotic fluid and told patients it contained stem cells that would cure a variety of conditions, charging them four times what the fluid cost her to inject them with it. Garrison charged Derges with false statements over the use of the fluid, as well as illegal distribution of controlled substances and wire fraud in relation to other activities at the clinics she runs.

Among long posts on her Facebook page professing her innocence, Derges posted a picture of David and Goliath, writing, I actually thought that I was making a difference. What I didnt account for was how much satan would fight back.

Whatever the truth of the allegations in Derges' specific case, by charging astate representative, Garrison has highlighted what is definitely a growing problem: deceptive use of stem cell therapies.

Multipotent stem cells have the remarkable capacity to convert into the cells that make up many bodily tissues. The hematopoietic stem cells have been used for decades to treat leukemia with well-proven results. Hundreds of other applications are either under investigation in the laboratory, or currently in clinical trials, but a much smaller number have been approved by America's FDA and equivalent bodies worldwide.

Understandably, many people don't feel able to wait, making them vulnerable to quack doctors for whom stem cells are the 21st Century snake oil. Unlike embryonic stem cells, which often originate from abortions, amniotic stem cells are seen as an alternative acceptable to pro-life individuals. However, having been discovered more recently, research into them is less advanced, making any therapeutic value speculative.

Dirges' vocal opposition to abortionpresumably made amniotic cells attractive to her for this reason, but Garrison alleges the fluid Derges was using didn't even contain stem cells. Moreover, he claims the University of Utah where Derges bought the fluid told her that, so she would have known it couldn't possibly have been effective.

Derges gained a medical degree from the Caribbean Medical University in Curaao and ran a series of low-cost medical clinics, where volunteers saw patients and recommended to her what medication to prescribe. Although licensed as an assistant physician, Derges was not accepted into a post-graduate residency program and was not licensed as a physician. She fought to change licensing rules, and ran for Missouri state District 140, narrowly winning the Republican primary before being unopposed last November. Since being elected, Derges has made changing the law on physician licensing her first priority.

In a statement, Garrison allegedDerges used the fluid on patients with everything from Lyme disease to erectile dysfunction and kidney disease, despite the improbability a single fluid would cure such different ills. Although Derges' clinics are famous for charging just $5 for an ordinary visit, the costs of this treatment averaged $40,000 per patient.

The program came to Garrison's attention after she appeared on television claiming the same amniotic fluid should be used to treat COVID-19 and making similar claims on Facebook.

H/T Springfield News Leader

Original post:
Missouri State Representative Indicted Over Alleged Stem Cell Therapy Scam - IFLScience

Posted in Cell Therapy | Comments Off on Missouri State Representative Indicted Over Alleged Stem Cell Therapy Scam – IFLScience

$5.6 Billion Cell Therapy Technologies Markets, 2025 with Thermo Fisher Scientific, Merck KGaA, and Danaher Dominating – Yahoo Finance

Posted: February 2, 2021 at 11:50 pm

Dublin, Feb. 01, 2021 (GLOBE NEWSWIRE) -- The "Cell Therapy Technologies Market Report - Global Forecast to 2025" report has been added to ResearchAndMarkets.com's offering.

The Global Cell Therapy Technologies Market is Projected to Reach USD 5.6 Billion by 2025 from USD 2.8 Billion in 2020, at a CAGR of 14.4% from 2020 to 2025.

The growth of this market is driven by the rising government investments in cell-based research, increasing incidence of chronic and infectious diseases, a large number of oncology-related cell therapy clinical trials, and increasing GMP certifications for cell therapy production facilities. Also, the emergence of iPSCs as an alternative to ESCs and increased focus on personalized medicine to offer an opportunity for the growth of the market during the forecast period.

Consumables are expected to hold the largest share of the cell therapy technologies market, by product in 2020.

On the basis of product, the market is segmented into consumables, equipment, and systems & software. The consumables segment accounted for the largest share of the cell therapy technologies market in 2019. Factors such as increasing investments by companies to develop advanced products as well as government initiatives for enhancing cell-based research are contributing to the growth of the cell therapy consumables market.

T-cells are expected to hold the largest share of the cell therapy technologies market, in 2020.

On the basis of cell type, the market is segmented into, T-cells, stem cells, and other cells. In 2019, T-cells accounted for the largest share of the cell therapy technologies market. Favorable government initiatives and the increasing demand for T-cell therapies are the key factors driving the growth of this segment.

Cell processing is expected to hold the largest share of the cell therapy technologies market in 2020.

On the basis of process, the market is segmented into cell processing, cell preservation, distribution and handling, and process monitoring and quality control. The cell processing segment dominated the market in 2019. This segment is expected to grow at the highest CAGR during the forecast period. The cell processing stage makes the highest use of cell therapy instruments and media, especially during culture media processing. This is the major factor responsible for the large share and high growth of this segment.

Story continues

Biopharmaceutical & biotechnology companies and CROs segment commanded the largest share of the cell therapy technologies market in 2020

By end-user, the cell therapy technologies market is segmented into biopharmaceutical & biotechnology companies and CROs and research institutes and cell banks. Biopharmaceutical & biotechnology companies and CROs dominate the market and are expected to grow at the highest CAGR. The large share of this regional segment can primarily be attributed to the high burden of chronic diseases and increasing R&D activities in the pharmaceutical and biotechnology industries.

North America commanded the largest share of the cell therapy technologies market in 2020.

On the basis of region, the cell therapy technologies market is segmented into North America, Europe, Asia Pacific, and Rest of the World. In 2019, North America commanded the largest share of the cell therapy technologies market. The large share of this market segment can be attributed to the increasing incidence of CVD, increasing healthcare expenditure, growing disposable income, growing healthcare awareness, and the availability of technologically advanced devices in the region.

Some of the major players operating in this market are Thermo Fisher Scientific Inc. (US), Merck KGaA (Germany) and Danaher Corporation (US).

Frequently Asked Questions:

What are the growth opportunities in the cell therapy technologies market across major regions in the future?

Which type of cells are expected to hold the largest share in the cell therapy technologies market?

What are the various cell therapy technologies product types and their respective market shares in the overall market?

Which region has a well-developed cell therapy technologies market?

What is the impact of COVID-19 on cell therapy technologies market?

Key Topics Covered:

1 Introduction

2 Research Methodology

3 Executive Summary

4 Premium Insights

5 Market Overview

6 Cell Therapy Technologies Market, by Product

7 Cell Therapy Technologies Market, by Process

8 Cell Therapy Technologies Market, by Cell Type

9 Cell Therapy Technologies Market, by End-user

10 Cell Therapy Technologies Market, by Region

11 Competitive Landscape & Company Profiles

Avantor, Inc.

Becton, Dickinson and Company

Bio-Techne Corporation

Cellgenix GmbH

Corning Incorporated

Danaher Corporation

Fresenius Medical Care AG & Co. KGaA

Fujifilm Irvine Scientific

Hemasoft

Ixcells Biotechnology

L7 Informatics

Lonza Group

Mak-System

Maxcyte

Merck KGaA

Miltenyi Biotec GmbH

Organabio, LLC

Roosterbio

Sartorius Ag

Sirion Biotech GmbH

Stemcell Technologies

Terumo Bct, Inc.

Thermo Fisher Scientific

Werum IT Solutions GmbH

Wilson Wolf Corporation

For more information about this report visit https://www.researchandmarkets.com/r/xonbsl

Research and Markets also offers Custom Research services providing focused, comprehensive and tailored research.

Originally published February 1, 2021, 8:33 AM

Continue reading here:
$5.6 Billion Cell Therapy Technologies Markets, 2025 with Thermo Fisher Scientific, Merck KGaA, and Danaher Dominating - Yahoo Finance

Posted in Cell Therapy | Comments Off on $5.6 Billion Cell Therapy Technologies Markets, 2025 with Thermo Fisher Scientific, Merck KGaA, and Danaher Dominating – Yahoo Finance

Page 769«..1020..768769770771..780790..»