Heart Disease And Cardiac Failure: The Role Of Stem Cells …

Stem cell therapy for cardiac failure has astounded the medical profession and resulted in the immediate implementation of clinical trials to fast-track regulation and implementation. The available treatment protocol for ..

Heart Disease And Cardiac Failure: The Role Of Stem Cells

Stem cell therapy for cardiac failure has astounded the medical profession and resulted in the immediate implementation of clinical trials to fast-track regulation and implementation. The available treatment protocol for cardiac failure has been used successfully since 2007 and is the same procedure that is to be followed in future FDA-approved clinical trials. Patients with extremely poor ejection fractions have responded well enough to return to a normal lifestyle with minimal medication needs.

Stem cell therapy and cardiac failure

Stem cell therapy is the latest tool in regenerative cardiac medical therapy. Its potential for use in cardiovascular disease has only recently been recognized in clinical trials. A randomized study was conducted in 20 patients to deploy stem cells as an adjuvant to conventional revascularization therapy in patients with congestive heart failure. 1

Injections of adult stem cells into damaged heart tissue significantly improved heart function in patients with severe congestive heart failure, according to results of the first prospective randomized trial of the experimental therapy. 4

The results were astounding in that this study proved that in the early stages of recovery the stem cell transplant group fared the same as the surgical group, but at one month post-treatment, the gap widened to show that the stem cell treated group started doing better and the surgical group stagnated. This carried through for the rest of the study period and by six months the stem cell treated group had improved an average of 46% as compared to only 35% in the surgically treated group.1 The head researcher for this study stated their findings provide the first convincing evidence that transplantation of adult stem cells that promote growth of blood vessels and heart muscle can be a viable treatment for congestive heart failure.4

It is now becoming widely accepted that stem cells can repair heart tissue and now the structure of clinical trials seems to be focused on how many and what type of cells to use and not whether this works or not. During the writing of this article the author noted 6 FDA-approved clinical trials currently recruiting patients. 2

In 2008, Mayo Clinic investigators have demonstrated that stem cells can be used to regenerate heart tissue to treat dilated cardiomyopathy, one of the causes of cardiac failure. Interesting to note here is that the responses also seemed to start after one month as in the first study mentioned above.3

We see that by using the correct stem cells augmented by RegAmp in a minimally invasive procedure we achieve the same results, which according to our track record, is, on average a 40% improvement over baseline after three months. These are the best results available today and are borne out by their similarity to results that have been attained in animal and human studies in FDA-approved clinical trials. We have not experienced any adverse events in any of our patients during this safe and effective procedure, which can be performed at any one of the Regenecell clinics worldwide.

Additional informaton can be found at http://www.regenecell.com

References:
1. Patel A N et al. Surgical treatment for congestive heart failure with autologous adult stem cell transplantation: A prospective randomized study. J Thor & Card Surgery. Vol 130, Issue 6, Pages 1631-1638 (December 2005).
2. Clinicaltrials.gov
3. Physorg.com
4. mirm.pitt.edu/news

Dr Jeff Peimer MBChB (UCT) is a medical doctor with extensive experience in regenerative medicine, mental health and emergency medicine. He is the medical director of Regenecell, a company specialising in stem cell treatments. Jeff is consulted extensively by patients and their families who need help evaluating stem cell treatment. His main area of interest is the treatment of severe disease and injury by using umbilical cord stem cells.
He lives in Cape Town with his wife and two sons.

Visit the Regenecell website for more on stem cell therapy or Jeff’s Facebook page here

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Heart Disease And Cardiac Failure: The Role Of Stem Cells ...