'Stem cells' created in less than 30 minutes in 'groundbreaking' discovery

Professor Austin Smith of Cambridge University, writing in the Journal Nature said the new cells could be seen as a blank slate from which any cell could emerge depending on its environment.

Remarkably, instead of triggering cell death or tumour growth as might be expected, a new cell state emerges that exhibits and unprecedented potential for differentiation into every possible cell type, he said.

The discovery has been hailed as incredible by scientists who believe it will speed up the advancement of personalised medicine.

Stem cells offer the possibility of a renewable source of replacement cells and tissues to treat diseases including Alzheimer's, spinal cord injury, stroke, heart disease, diabetes, osteoarthritis, and rheumatoid arthritis.

They could be used to regenerate organs, stimulate the growth of new blood vessels, or create skin grafts.

(This) approach in the mouse is the most simple, lowest cost and quickest method to generate pluripotent cells from mature cells, said Professor Chris Mason, Chair of Regenerative Medicine Bioprocessing, at University College London.

If it works in man, this could be the game changer that ultimately makes a wide range of cell therapies available using the patients own cells as starting material the age of personalised medicine would have finally arrived.

Who would have thought that to reprogram adult cells to an embryonic stem cell-like (pluripotent) state just required a small amount of acid for less than half an hour an incredible discovery.

Professor Mason said the development was likely to speed up the development of technology in everyday clinical practice although warned that was still years away.

Dr Dusko Ilic, Reader in Stem Cell Science, Kings College London, said the findings were revolutionary.

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'Stem cells' created in less than 30 minutes in 'groundbreaking' discovery